Zobrazeno 1 - 10
of 672
pro vyhledávání: '"J E, Saavedra"'
Publikováno v:
Xenobiotica. 32:339-347
1. The single-dose plasma pharmacokinetics of O(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) following intravenous (i.v.) and intraperitoneal (i.p.) bolus administration to the male C57BL/6 mouse was studied in an effort to chara
Publikováno v:
Russian Chemical Bulletin; May2024, Vol. 73 Issue 5, p1328-1333, 6p
Autor:
J. E. Saavedra
Publikováno v:
ChemInform. 22
ChemInform Abstract: β-Keto Nitrosamines as Synthetic Equivalents of α-Methylene Alkanolamino Anions
Autor:
J. E. Saavedra, D. W. Farnsworth
Publikováno v:
ChemInform. 22
Nitric oxide (NO) is a major effector molecule in cancer prevention. A number of studies have shown that NO prodrug JS-K (O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate) induces apoptotic cell death in vitro and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15efd5c3e17fd279058c37543120462a
https://europepmc.org/articles/PMC2854646/
https://europepmc.org/articles/PMC2854646/
Autor:
J E, Saavedra, A, Srinivasan, C L, Bonifant, J, Chu, A P, Shanklin, J L, Flippen-Anderson, W G, Rice, J A, Turpin, K M, Davies, L K, Keefer
Publikováno v:
The Journal of organic chemistry. 66(9)
Ions of structure R(2)N[N(O)NO](-) and their alkylation products have seen increasing use as nitric oxide (NO)-generating agents for biomedical research applications. Here we show that such diazeniumdiolate anions can readily displace halide from a v
Autor:
R, Ricciardi, D P, Foley, S H, Quarfordt, J E, Saavedra, L K, Keefer, S M, Wheeler, S E, Donohue, M P, Callery, W C, Meyers
Publikováno v:
Transplantation. 71(2)
The role of nitric oxide (NO) in ischemia reperfusion (I/R) injury is controversial as both beneficial and harmful effects have been reported. We explored the potential role of a pharmacological agent recently shown to generate NO metabolically in th
Publikováno v:
Revista de neurologia. 28(9)
Cinnarizine is a calcium-entry blocker drug used in vertiginous disorders; among its most rare adverse effects appear extrapyramidal symptoms and depression, these effects can persist during weeks, months or years after the withdrawal of the drug and
Autor:
H C, Champion, T J, Bivalacqua, R, Wang, P J, Kadowitz, L K, Keefer, J E, Saavedra, J A, Hrabie, P C, Doherty, W J, Hellstrom
Publikováno v:
The Journal of urology. 161(6)
The effects of novel nitric oxide (NO) donors administered intracavernosally and transurethrally on erectile function in the anesthetized cat were evaluated.In pentobarbital-anesthetized cats, increases in intracavernosal pressure, penile length, and
Autor:
Wu, Xumeng1,2 (AUTHOR), Zhou, Ziqi2,3 (AUTHOR), Li, Kai2,3 (AUTHOR), Liu, Shaoqin1,2,3 (AUTHOR) shaoqinliu@hit.edu.cn
Publikováno v:
Advanced Science. Apr2024, Vol. 11 Issue 16, p1-39. 39p.