Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J E, Royland"'
Publikováno v:
Journal of Neuroscience Research. 47:626-635
The purpose of this study was to characterize the selenium requirement for the normal differentiation of oligodendrocyte lineage cells. In primary mixed glial cultures prepared from newborn rat brains, the overall growth of cultures, as seen from the
Publikováno v:
Life Sciences. 54:545-554
The purpose of this study was to test whether the lack of testicular growth found in suspended rats would affect testosterone production in a way that might have consequences on muscle atrophy and function studies. Body and testes weight, food consum
Publikováno v:
Journal of Neuroscience Research. 36:399-404
Glucose deprivation was employed to model caloric undernutrition in newborn rat mixed glial cultures. Six day-old cultures were placed in serum-free media containing glucose concentrations from 0.55 mg/ml to 10 mg/ml. The expression of the myelin PLP
Publikováno v:
Journal of Neuroscience Research. 31:745-750
The effect of retinoic acid (RA) on the expression of myelin-specific genes, i.e., proteolipid protein (PLP) and myelin-associated glycoprotein (MAG) in rat glioma C6 cells, was analyzed by Northern blot hybridization. RA-treatment increased the stea
Publikováno v:
Metabolic brain disease. 14(3)
We have previously demonstrated that the developmental upregulation of myelin-specific genes in mixed glial cultures is strongly attenuated by hypoglycemia. The present study was designed to evaluate the effect of hypoglycemia on differentiation-depe
Publikováno v:
Journal of neuroscience research. 47(6)
The purpose of this study was to characterize the selenium requirement for the normal differentiation of oligodendrocyte lineage cells. In primary mixed glial cultures prepared from newborn rat brains, the overall growth of cultures, as seen from the
Publikováno v:
Neurotoxicology. 17(3-4)
Evidence obtained from studies on the mechanisms of action of dopaminergic neurotoxins suggests that glial cells may play an important role in neurodegenerative processes. A possible link between the function of glial cells and nerve cell damage coul
Publikováno v:
Journal of neuroscience research. 39(3)
The methylation status of a 4.4-kb 5′ end of the myelin-associated glycoprotein (MAG) gene was assessed in cells with different levels of transcriptional activity of the gene, i.e., liver, brain, O-2A oligodendrocyte precursors cells, mature oligod
Publikováno v:
Neurochemistry international. 21(2)
Brains from young (20 day old) and adult rats were used to compare myelin yields obtained by sedimentation and flotation techniques. The flotation method consistently gave approx 70% higher yields of myelin than the sedimentation method. Both myelin
Publikováno v:
Journal of neuroscience research. 31(3)
A model culture system of C6 rat glioma cells was used to test the involvement of cAMP in the regulation of the myelin PLP and MAG genes. The treatment of cells with isoproterenol (10(-5) to 10(-8) M) upregulated the expression of the PLP and MAG gen