Zobrazeno 1 - 10
of 801
pro vyhledávání: '"J E, Rivier"'
Autor:
J. E. RIVIER, A. G. CRAIG, E. MAHE, A. RABINOVICH, D. KIRBY, R. KAISER, J. PORTER, M. T. M. DE MIRANDA, A. DE MIRANDA, ET AL. ET AL.
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1a18a87104ded585ba2345ff777213
https://doi.org/10.1002/chin.199513329
https://doi.org/10.1002/chin.199513329
Autor:
J. E. Rivier, Bradford J. Stevenson, Kathleen A. Clark, Kent G. Golic, Y. S. Rong, Pradip K. Bandyopadhyay, Baldomero M. Olivera
Publikováno v:
Insect molecular biology. 15(2)
To investigate structure-function relationships in gamma-glutamyl carboxylases, the enzyme from Drosophila melanogaster was characterized. Four cysteine residues were shown to be important determinants for enzymatic activity. Native Drosophila substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43db47609618c44ae5777cf320cea819
https://pubmed.ncbi.nlm.nih.gov/16640725
https://pubmed.ncbi.nlm.nih.gov/16640725
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 65(2)
Degarelix is a potent very long-acting GnRH antagonist after subcutaneous administration. In this paper, we describe the synthesis of two analogs of degarelix incorporating racemic 3-(2-methoxy-5-pyridyl)-alanine (2-OMe-5Pal, 5) at position 3. The tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0435a81fb1ebe93b58e2fc8173c41d9d
https://pubmed.ncbi.nlm.nih.gov/15705170
https://pubmed.ncbi.nlm.nih.gov/15705170
Autor:
G M, Somoza, D W, Lescheid, L A, Miranda, F L, Lo Nostro, L, Magliulo-Cepriano, A D, Montaner, M P, Schreibman, J E, Rivier, N M, Sherwood
Publikováno v:
Biology of reproduction. 67(6)
Molecular variants of GnRH were characterized by reverse-phase, high-performance liquid chromatography from brain extracts of fish in three different orders: Synbranchiformes (swamp eel [Synbranchus marmoratus]), Cyprinidontiformes (platyfish [Xiphop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bdfccf0fdde6785b95f648126d8cb3b
https://pubmed.ncbi.nlm.nih.gov/12444064
https://pubmed.ncbi.nlm.nih.gov/12444064
Autor:
J E, Rivier, G, Jiang, R S, Struthers, S C, Koerber, J, Porter, L A, Cervini, D A, Kirby, A G, Craig, C L, Rivier
Publikováno v:
Journal of medicinal chemistry. 43(5)
In three earlier papers, the structures and biological potencies of numerous mono- and dicyclic antagonists of GnRH were reported. Among these, two families, each containing two to four members were identified that had very high antagonist potencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fc00dd273345a73ae7212380b1b6925
https://pubmed.ncbi.nlm.nih.gov/10715149
https://pubmed.ncbi.nlm.nih.gov/10715149
Autor:
J, Carolsfeld, J F, Powell, M, Park, W H, Fischer, A G, Craig, J P, Chang, J E, Rivier, N M, Sherwood
Publikováno v:
Endocrinology. 141(2)
The evolution of GnRH and the role of multiple forms within the brain are examined. Three forms of GnRH were purified from the brain of Pacific herring (Clupea harengus pallasi) and characterized using Edman degradation and mass spectrometry. Two for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb53b2a314b736eae352da6dcc2f8cc0
https://pubmed.ncbi.nlm.nih.gov/10650929
https://pubmed.ncbi.nlm.nih.gov/10650929
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(2)
The characteristics of a high-affinity antagonist radioligand are compared with those a high-affinity agonist in binding to the cloned corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2) and to the native receptors that exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3462df984578623f21c407b61e022ee
https://pubmed.ncbi.nlm.nih.gov/9918582
https://pubmed.ncbi.nlm.nih.gov/9918582
Publikováno v:
Endocrinology. 140(1)
Urocortin (Ucn) is a newly identified mammalian member of the CRF family of peptides. Ucn activates CRF receptors (both CRF-R1 and CRF-R2) with greater potency than CRF itself, suggesting that Ucn may play an endogenous role in eliciting (at least so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::695e0cf5cc179f03d11daabcbc94739a
https://pubmed.ncbi.nlm.nih.gov/9886809
https://pubmed.ncbi.nlm.nih.gov/9886809
Autor:
A G, Craig, E C, Jimenez, J, Dykert, D B, Nielsen, J, Gulyas, F C, Abogadie, J, Porter, J E, Rivier, L J, Cruz, B M, Olivera, J M, McIntosh
Publikováno v:
The Journal of biological chemistry. 272(8)
We report a novel post-translational modification involving halogenation of tryptophan in peptides recovered from the venom of carnivorous marine cone snails (Conus). The residue, L-6-bromotryptophan, was identified in the sequence of a heptapeptide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49b112251ad9035fc6cd43aa7960e896
https://pubmed.ncbi.nlm.nih.gov/9030520
https://pubmed.ncbi.nlm.nih.gov/9030520
Publikováno v:
Depression and anxiety. 6(1)
Neuropeptide Y (NPY) has neuromodulatory actions on multiple brain functions including endocrine, behavioral, and circadian processes and has been implicated in the pathophysiology of both anxiety and depression. Behavioral studies suggest that NPY i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f4b39617f0aa4753fb9203c5f937196
https://pubmed.ncbi.nlm.nih.gov/9394869
https://pubmed.ncbi.nlm.nih.gov/9394869