Zobrazeno 1 - 10
of 203
pro vyhledávání: '"J E, Lucas"'
Autor:
Johnathan S. L. Goves, Kelsey E. Joyce, Sophie Broughton, Julian Greig, Kimberly Ashdown, Arthur R. Bradwell, Samuel J. E. Lucas
Publikováno v:
Experimental Physiology, Vol 109, Iss 12, Pp 2057-2072 (2024)
Abstract Acute mountain sickness (AMS) causes serious illness for many individuals ascending to high altitude (HA), although preventable with appropriate acclimatisation. AMS is a clinical diagnosis, with symptom severity evaluated using the Lake Lou
Externí odkaz:
https://doaj.org/article/9019a8dde74743c19068dcce90950478
Autor:
Kelsey E. Joyce, Kimberly Ashdown, John P. Delamere, Chris Bradley, Christopher T. Lewis, Abigail Letchford, Rebekah A. I. Lucas, Will Malein, Owen Thomas, Arthur R. Bradwell, Samuel J. E. Lucas
Publikováno v:
Experimental Physiology, Vol 109, Iss 11, Pp 1856-1868 (2024)
Abstract Acute mountain sickness (AMS) is a well‐studied illness defined by clinical features (e.g., headache and nausea), as assessed by the Lake Louise score (LLS). Although obvious in its severe form, early stages of AMS are poorly defined and e
Externí odkaz:
https://doaj.org/article/e2fbe17f226e41a3ad1178b236ca73b6
Autor:
Jack Feron, Foyzul Rahman, Sindre H Fosstveit, Kelsey E Joyce, Ahmed Gilani, Hilde Lohne-Seiler, Sveinung Berntsen, Karen J Mullinger, Katrien Segaert, Samuel J E Lucas
Publikováno v:
NeuroImage, Vol 303, Iss , Pp 120919- (2024)
Brain vascular health worsens with age, as is made evident by resting grey matter cerebral blood flow (CBFGM) reductions and lengthening arterial transit time (ATTGM). Exercise training can improve aspects of brain health in older adults, yet its eff
Externí odkaz:
https://doaj.org/article/672c50f8d2234edcb9693d921c71acee
Autor:
Fendi Pradana, Tarondeep Nijjar, Phoebe A. Cox, Paul T. Morgan, Tim Podlogar, Samuel J. E. Lucas, Mark T. Drayson, Francesca A. M. Kinsella, Alex J. Wadley
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionPeripheral blood stem cell (PBSC) donation is the primary procedure used to collect hematopoietic stem and progenitor cells (HSPCs) for hematopoietic stem cell transplantation. Single bouts of exercise transiently enrich peripheral blood
Externí odkaz:
https://doaj.org/article/e816c4585b1a4d5697a22e142d5557cc
Autor:
Daniel D Hodgkiss, Gurjeet S Bhangu, Carole Lunny, Catherine R Jutzeler, Shin-Yi Chiou, Matthias Walter, Samuel J E Lucas, Andrei V Krassioukov, Tom E Nightingale
Publikováno v:
PLoS Medicine, Vol 20, Iss 11, p e1004082 (2023)
BackgroundA low level of cardiorespiratory fitness [CRF; defined as peak oxygen uptake ([Formula: see text]O2peak) or peak power output (PPO)] is a widely reported consequence of spinal cord injury (SCI) and a major risk factor associated with chroni
Externí odkaz:
https://doaj.org/article/4c3425d9ecb741ff9cd4185477b474e0
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Background and aims: Sex differences in the rate and occurrence of cerebrovascular diseases (e.g., stroke) indicate a role for female sex hormones (i.e., oestrogen and progesterone) in cerebrovascular function and regulation. However, it remains uncl
Externí odkaz:
https://doaj.org/article/8aac5eeafcb74e39b7ad4414326b7692
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The growing prevalence of physical inactivity in the population highlights the urgent need for a more comprehensive understanding of how sedentary behaviour affects health, the mechanisms involved and what strategies are effective in counteracting it
Externí odkaz:
https://doaj.org/article/f27b3188b5dc4713adcf29fb873acb70
Autor:
Gabriele Gratton, Samuel R. Weaver, Claire V. Burley, Kathy A. Low, Edward L. Maclin, Paul W. Johns, Quang S. Pham, Samuel J. E. Lucas, Monica Fabiani, Catarina Rendeiro
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Cocoa flavanols protect humans against vascular disease, as evidenced by improvements in peripheral endothelial function, likely through nitric oxide signalling. Emerging evidence also suggests that flavanol-rich diets protect against cognit
Externí odkaz:
https://doaj.org/article/adc806851d454f9ebddaaa32ffbb9e74
Autor:
Patrice Brassard, Lawrence Labrecque, Jonathan D. Smirl, Michael M. Tymko, Hannah G. Caldwell, Ryan L. Hoiland, Samuel J. E. Lucas, André Y. Denault, Etienne J. Couture, Philip N. Ainslie
Publikováno v:
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept suggested a relatively broad mean arterial pressure range (~60–150 m
Externí odkaz:
https://doaj.org/article/b5bff2ce6f6c46edae53b5c80e2c04e8
Autor:
Bethany D. Skinner, Rebecca J. Davies, Samuel R. Weaver, N. Tim Cable, Samuel J. E. Lucas, Rebekah A. I. Lucas
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sex differences in cerebrovascular disease rates indicate a possible role for ovarian sex steroid hormones in cerebrovascular function. To synthesise and identify knowledge gaps, a systematic review and meta-analysis was conducted to assess how ovari
Externí odkaz:
https://doaj.org/article/e1827604edae4647981112887e9b8719