Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J E, Kralic"'
Autor:
G E, Homanics, F P, Elsen, S-W, Ying, A, Jenkins, C, Ferguson, B, Sloat, S, Yuditskaya, P A, Goldstein, J E, Kralic, A L, Morrow, N L, Harrison
Publikováno v:
Genes, brain, and behavior. 4(1)
In mammalian species, inhibition in the brain is mediated predominantly by the activation of GABAA receptors. We report here changes in inhibitory synaptic function and behavior in a mouse line harboring a gain-of-function mutation at Serine 270 (S27
Publikováno v:
Journal of neurochemistry. 86(3)
The molecular mechanisms that underlie ethanol dependence involve alterations in the functional properties and subunit expression of GABAA receptors. Chronic ethanol exposure decreases GABAA receptor alpha1 subunits and increases alpha4 subunit level
Autor:
R M, Mihalek, B J, Bowers, J M, Wehner, J E, Kralic, M J, VanDoren, A L, Morrow, G E, Homanics
Publikováno v:
Alcoholism, clinical and experimental research. 25(12)
The gamma-aminobutyric acid type A receptors (GABARs) are involved in mediating some of the behavioral effects of beverage alcohol (ethanol). However, the unique pharmacological and behavioral responses conferred by each of the various receptor subun