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Akademický článek

Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes.

Autor: Gabriele Piconi, Alexander H Peden, Marcelo A Barria, Alison J E Green

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218509 (2019)

Sporadic Creutzfeldt-Jakob disease (sCJD) is a transmissible, rapidly progressive and fatal neurodegenerative disease. The transmissible agent linked to sCJD is composed of the misfolded form of the host-encoded prion protein. The combination of hist

Externí odkaz: https://doaj.org/article/d4a2ee5eb46949bdabb0f1f580d9693b

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Brain and Cerebrospinal Fluid α-Synuclein Real-Time Quaking-Induced Conversion Identifies Lewy Body Pathology in LRRK2-PD

Autor: Alicia Garrido, Graham Fairfoul, Eduardo Tolosa, Maria J. Marti, Mario Ezquerra, Alison J E Green

Publikováno v: Garrido, A, Fairfoul, G, Tolosa, E, Marti, M J, Ezquerra, M & Green, A J E 2022, ' Brain and Cerebrospinal Fluid α-Synuclein Real-Time Quaking-Induced Conversion Identifies Lewy Body Pathology in LRRK2-PD ', Movement Disorders . https://doi.org/10.1002/mds.29284

BACKGROUND: The neuropathology of Parkinson's disease (PD) associated with leucine-rich repeat kinase 2 (LRRK2) mutations (LRRK2-PD) is heterogeneous and varies with the type of mutation. There are only a few studies evaluating seeding aggregation as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c985671e13c5612ef71b94032408d7c
https://pubmed.ncbi.nlm.nih.gov/36471633

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Validation of Revised International Creutzfeldt-Jakob Disease Surveillance Network Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease

Publikováno v: Watson, N, Hermann, P, Ladogana, A, Denouel, A, Baiardi, S, Colaizzo, E, Giaccone, G, Glatzel, M, Green, A J E, Haïk, S, Imperiale, D, Mackenzie, J, Moda, F, Smith, C, Summers, D, Tiple, D, Vaianella, L, Zanusso, G, Pocchiari, M, Zerr, I, Parchi, P, Brandel, J & Pal, S 2022, ' Validation of Revised International Creutzfeldt-Jakob Disease Surveillance Network Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease ', JAMA Network Open, vol. 5, no. 1, pp. e2146319 . https://doi.org/10.1001/jamanetworkopen.2021.46319

Importance: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly lethal disease. Rapid, accurate diagnosis is imperative for epidemiological surveillance and public health activities to exclude treatable differentials and facilitate supportive care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5ddb1f08e07c128c1b6b02464ea1e7
http://hdl.handle.net/11585/871463

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Akademický článek

A Naturally Occurring Bovine Tauopathy Is Geographically Widespread in the UK.

Autor: Martin Jeffrey, Pedro Piccardo, Diane L Ritchie, James W Ironside, Alison J E Green, Gillian McGovern

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129499 (2015)

Many human neurodegenerative diseases are associated with hyperphosphorylation and widespread intra-neuronal and glial associated aggregation of the microtubule associated protein tau. In contrast, animal tauopathies are not reported with only senesc

Externí odkaz: https://doaj.org/article/e0e775d0685e496f842a4f795037e8a6

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Impact of the COVID-19 pandemic on Creutzfeldt-Jakob disease surveillance and patient care in the United Kingdom

Autor: Neil Watson, Jack Kirby, Hatice Kurudzhu, Margaret Leitch, Janet MacKenzie, Blaire Smith‐Bathgate, Colin Smith, David Summers, Alison J. E. Green, Suvankar Pal

Publikováno v: Watson, N, Kirby, J, Kurudzhu, H, Leitch, M, Mackenzie, J, Smith-bathgate, B, Smith, C, Summers, D, Green, A J E & Pal, S 2021, ' Impact of the COVID-19 pandemic on Creutzfeldt–Jakob disease surveillance and patient care in the United Kingdom ', European Journal of Neurology . https://doi.org/10.1111/ene.15228

Creutzfeldt-Jakob disease (CJD) is lethal and transmissible. We assessed the impact of the COVID-19 pandemic on UK CJD surveillance. We hypothesized that (i) disruptions prolonged diagnostic latency; (ii) autopsy rates declined; and (iii) COVID-19 in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06d7772d47b8b6144c5400f079849ef
https://pubmed.ncbi.nlm.nih.gov/34941016

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In Vivo Imaging of Fibroblast Activity Using a 68Ga-Labeled Fibroblast Activation Protein Alpha (FAP-α) Inhibitor: Study in a Mouse Rotator Cuff Repair Model

Autor: Daoyun Chen, Samuel J. E. Green, Scott A. Rodeo, Xueying Zhang, John W. Babich, Xiang-Hua Deng

Publikováno v: The Journal of bone and joint surgery. American volume. 103(10)

Background Rotator cuff repair site failure is a well-established clinical concern. Tendon-to-bone healing is initiated by inflammatory mediators followed by matrix synthesis by fibroblasts. The kinetics of fibroblast accumulation and activity are cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead09718d2bac3b5bed0a8afe26f8790
https://pubmed.ncbi.nlm.nih.gov/33587512

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Cerebrospinal Fluid α-Synuclein Detection by RT-QuIC in Patients with Isolated Rapid-Eye-Movement Sleep Behaviour Disorder

Autor: Alex Iranzo, Graham Fairfoul, AnutraChumbala Na Ayudhaya, Monica Serradell, Ellen Gelpi, Isabel Vilaseca, Raquel Sanchez-Valle, Carles Gaig, Joan Santamaria, Eduard Tolosa, Renata L. Riha, Alison J. E. Green

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7262a9763908d0e080a2463a12f8390c
https://doi.org/10.2139/ssrn.3556635

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Green Aviation – Encyclopedia of Aerospace Engineering R. Agarwal et al.John Wiley and Sons, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK. 2016. 514pp. Illustrated. £160. ISBN 978-1-118-86635-1

Autor: J. E. Green

Publikováno v: The Aeronautical Journal. 122:2034-2038

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d4462615fcb70a1a8efb48a017a44ac
https://doi.org/10.1017/aer.2018.130

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Bauxite residue (red mud) as a pulverised fuel ash substitute in the manufacture of lightweight aggregate

Autor: J. E. Green, Bamdad Ayati, Chloe J. Molineux, Stuart Connop, Darryl J. Newport, Chuang Wang

Publikováno v: Journal of Cleaner Production. 112:401-408

This study looked at the potential of bauxite residue or red mud to be used in the manufacture of lightweight aggregate in replacement of pulverised fuel ash (PFA), commonly used as a way of recycling problematic wastes. The percentage replacements o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bde6a936e5fba22049f32cffe62cae5
https://doi.org/10.1016/j.jclepro.2015.09.024

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Evaluation of SS-31 as a Potential Therapeutic Target in the Treatment of Tendinopathy

Autor: Xiang-Hua Deng, Scott A. Rodeo, Samuel J. E. Green, Hazel H. Szeto, Camila B. Carballo, Yusuke Nakagawa, Ying Zhang, Xueying Zhang

Publikováno v: Orthopaedic Journal of Sports Medicine

Objectives: The purpose of this study is to investigate the therapeutic potential of SS-31, a target to improve mitochondria function for the treatment of tendinopathy using human tenocytes. Methods: After IRB approval (IRB# 2018-0490), samples of no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865632e3c5781cdecd33832f8ecb9c1c
https://doi.org/10.1177/2325967120s00395

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