Zobrazeno 1 - 2
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pro vyhledávání: '"J E, Esplen"'
Autor:
V, Ramachandran, V E, Kostrubsky, B J, Komoroski, S, Zhang, K, Dorko, J E, Esplen, S C, Strom, R, Venkataramanan
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(10)
Troglitazone (TRO) is an insulin sensitizer used in the treatment of type II diabetes. TRO is known to increase the activity of cytochrome P-450 (CYP) 3A in vivo. We have investigated the effect of TRO on CYP3A protein content and the activity of CYP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8369dbde377946244acb6ceab5794c4b
https://pubmed.ncbi.nlm.nih.gov/10497147
https://pubmed.ncbi.nlm.nih.gov/10497147
Autor:
V E, Kostrubsky, V, Ramachandran, R, Venkataramanan, K, Dorko, J E, Esplen, S, Zhang, J F, Sinclair, S A, Wrighton, S C, Strom
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(8)
We have previously reported that paclitaxel (Taxol) is a potent inducer of cytochrome P-450 (CYP) 3A protein and CYP3A mRNA in human hepatocyte cultures. Here we report that Taxol increased CYP3A-dependent testosterone 6beta-hydroxylation in intact h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c7ab08c0c0524f67ed60c2caa277aad
https://pubmed.ncbi.nlm.nih.gov/10421615
https://pubmed.ncbi.nlm.nih.gov/10421615