Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J E, Cremer"'
Autor:
Victor W. Pike, J. E. Cremer, Raymond J. Dolan, S.P. Hume, Claudio Pascali, Christopher J. Bench, Adriaan A. Lammertsma
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology
The biologically active S -enantiomer of [ N -methyl- 11 C]citalopram was evaluated as a radioligand for in vivo labelling of the 5-hydroxytryptamine uptake site in brain, using ex vivo tissue counting in rats and positron emission tomography in man.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a02363b6273c67e5f3eb3c93a3f4a9b
https://doi.org/10.1016/0883-2897(92)90171-t
https://doi.org/10.1016/0883-2897(92)90171-t
Autor:
J. E. Cremer, Jolanta Opacka-Juffry, Sajinda K. Luthra, P.M. Bloomfield, David J. Brooks, Adriaan A. Lammertsma, R. G. Ahier, Ralph Myers, Susan P. Hume
Publikováno v:
Synapse. 12:47-54
Using conventional autoradiographic and tissue counting techniques, the experimental quantitation of in vivo kinetics of prospective or established radioligands for PET is animal and labour intensive. The present study tested the feasibility of using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef4a8478def13cf648f0672b98ca219
https://doi.org/10.1002/syn.890120106
https://doi.org/10.1002/syn.890120106
Autor:
J E Cremer, M Doran, B M Cullen, M. D. King, Stephen R. Williams, David G. Gadian, N. Van Bruggen
Publikováno v:
Stroke. 23:576-582
We sought to evaluate the application of T2-weighted and diffusion-weighted magnetic resonance imaging techniques in the study of a focal ischemic lesion in the rat brain. Unilateral cortical infarcts were induced using the photosensitive dye rose be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a718c3c99eee8b275583ff050509a28
https://doi.org/10.1161/01.str.23.4.576
https://doi.org/10.1161/01.str.23.4.576
Autor:
J. E. Cremer, Luisa G. Manjil, Ralph Myers, S.P. Hume, D.R. Turton, D. M. Bateman, Victor W. Pike, Sajinder K. Luthra, Beulah Cullen
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 19:159-166
PK 11195 is a selective ligand for the peripheral-type benzodiazepine binding site (PTBBS). There are few such sites in normal brain but their number increases in association with tissue necrosis. The time-course of appearance of PTBBS around a focal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d910dd246fc15ec54f3222e37d470b45
https://doi.org/10.1016/0883-2897(92)90003-h
https://doi.org/10.1016/0883-2897(92)90003-h
Autor:
G. W. Price, Adriaan A. Lammertsma, J. E. Cremer, N. D. Wood, R. S. J. Frackowiak, Sajinder K. Luthra, Christopher J. Bench, David R. Turton
Publikováno v:
Europe PubMed Central
A tracer kinetic procedure was developed for the measurement of monoamine oxidase type B (MAO-B) activity using L-[11C]deprenyl and positron emission tomography (PET). The kinetic model consisted of two tissue compartments with irreversible binding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb2c2a929664b61716ad0f8035b2187
https://doi.org/10.1038/jcbfm.1991.103
https://doi.org/10.1038/jcbfm.1991.103
Autor:
J. E. Cremer, Beulah Cullen, Richard S. J. Frackowiak, Ralph Myers, Luisa G. Manjil, Gary W. Price
Publikováno v:
Europe PubMed Central
PK 11195 is a selective and specific ligand for the peripheral-type benzodiazepine binding site. Its potential for in vivo visualisation of lesioned human brain using positron emission tomography (PET) is currently being assessed. The present study e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5a6880043ab6546b70238e0eb86019
https://doi.org/10.1038/jcbfm.1991.64
https://doi.org/10.1038/jcbfm.1991.64
Autor:
S.P. Hume, R. G. Ahier, Claudio Pascali, Ralph Myers, D. M. Bateman, Victor W. Pike, J. E. Cremer, D.R. Turton, Raymond J. Dolan, Luisa G. Manjil
Publikováno v:
International Journal of Radiation Applications and Instrumentation: Part B, Nuclear Medicine and Biology
In vivo autoradiography of [N-methly-3H]citalopram in rat brain shows a differential regional localization which correlates with the localization of 5-HT re-uptake binding sites defined in vitro. A comparison of the biodistribution of [N-mrthyl-3H]ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959609c5c77fd92753c0199da0e772be
https://doi.org/10.1016/0883-2897(91)90130-d
https://doi.org/10.1016/0883-2897(91)90130-d
Autor:
Victor W. Pike, Ralph Myers, J. E. Cremer, G. W. Price, R. G. Ahier, S.P. Hume, Luisa G. Manjil, Claudio Pascali, Sajinder K. Luthra
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes. 41:477-482
A method has been developed for labelling PK 14105 [N-methyl-N-(1-methyl-propyl)-1(2-fluoro-5-nitrophenyl)isoquinoline-3- carboxamide], a ligand that has high affinity and selectivity for peripheral type benzodiazepine binding sites (PBBS), with NCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e459b5aa7440d23f233c0d95bde68aed
https://doi.org/10.1016/0883-2889(90)90008-5
https://doi.org/10.1016/0883-2889(90)90008-5
Publikováno v:
Synapse. 7:169-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0735a80f44fa8bab2f34dc90258e967a
https://doi.org/10.1002/syn.890070210
https://doi.org/10.1002/syn.890070210
Publikováno v:
Cerebrovascular and brain metabolism reviews. 6(2)
Recent developments in the field of magnetic resonance imaging (MRI) have opened up new opportunities in the investigation of disease. This review seeks to illustrate how some of these advances have made MRI a powerful tool with which to study the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e3e16ea2f089133f1babe71524f3f74
https://pubmed.ncbi.nlm.nih.gov/8074964
https://pubmed.ncbi.nlm.nih.gov/8074964