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Akademický článek

Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory

Autor: Samantha J. Booth, Shruti Garg, Laura J. E. Brown, Jonathan Green, Gorana Pobric, Jason R. Taylor

Publikováno v: Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-18 (2023)

Abstract Background Neurofibromatosis type 1 (NF1) is a genetic neurodevelopmental disorder commonly associated with impaired cognitive function. Despite the well-explored functional roles of neural oscillations in neurotypical populations, only a li

Externí odkaz: https://doaj.org/article/79b0313aef65495fae8be475416c5231

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Akademický článek

Experimental investigation of training schedule on home-based working memory training in healthy older adults

Autor: Samantha J. Booth, Laura J. E. Brown, Jason R. Taylor, Gorana Pobric

Publikováno v: Frontiers in Psychology, Vol 14 (2023)

IntroductionThe efficacy of working memory training (WMT) for cognitive enhancement in healthy older adults has been extensively investigated. Typically, WMT results in improved performance on the training task, but limited or no transfer of improvem

Externí odkaz: https://doaj.org/article/bec579b516e74138813c4786e3020340

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Akademický článek

Co-design of a Smartphone App for People Living With Dementia by Applying Agile, Iterative Co-design Principles: Development and Usability Study

Autor: Sarah Fox, Laura J E Brown, Steven Antrobus, David Brough, Richard J Drake, Francine Jury, Iracema Leroi, Adrian R Parry-Jones, Matthew Machin

Publikováno v: JMIR mHealth and uHealth, Vol 10, Iss 1, p e24483 (2022)

BackgroundThe benefits of involving those with lived experience in the design and development of health technology are well recognized, and the reporting of co-design best practices has increased over the past decade. However, it is important to reco

Externí odkaz: https://doaj.org/article/8b16e56520874b1cbde4222d2871a419

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Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

Autor: Jason A Tye-Din, A James M Daveson, Gautam Goel, Kaela E Goldstein, Holly L Hand, Kristin M Neff, Alina Popp, Juha Taavela, Markku Maki, Jorma Isola, Leslie J Williams, Kenneth E Truitt, Robert P Anderson, Atoya Adams, Jane M Andrews, Clint E Behrend, Gregor J E Brown, Swee Lin Chen Yi Mei, Allan G Coates, Anthony J DiMarino, Hooi Ee, David E Elliott, Roger M Epstein, Bryan John Feyen, Ronald P Fogel, Keith Alan Friedenberg, Richard B Gearry, Michael S Gerdis, Michael J Goldstein, Vipin K Gupta, Robert John Holmes, Gerald J Holtmann, Samuel H Idarraga, George W James, Tim King, Terry D Klein, Sonia S Kupfer, Benjamin Lebwohl, Matthew John Lowe, Joseph A Murray, Eric B Newton, Dean Quinn, David M Radin, Timothy E Ritter, Helen Lee Stacey, Cynthia B Strout, Richard S Stubbs, Susan Lynn Thackwray, Vivek M Trivedi, John R Weber, Scott A Wilson

Publikováno v: The Lancet Gastroenterology & Hepatology. 8:446-457

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b188453544ecb53e309a7a38ba1a87cf
https://doi.org/10.1016/s2468-1253(22)00428-9

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Akademický článek

A Sensitive Whole Blood Assay Detects Antigen-Stimulated Cytokine Release From CD4+ T Cells and Facilitates Immunomonitoring in a Phase 2 Clinical Trial of Nexvax2 in Coeliac Disease

Autor: Melinda Y. Hardy, Gautam Goel, Amy K. Russell, Swee Lin G. Chen Yi Mei, Gregor J. E. Brown, Suyue Wang, Evan Szymczak, Ruan Zhang, Kaela E. Goldstein, Kristin M. Neff, Leslie J. Williams, Kenneth E. Truitt, John L. Dzuris, Jason A. Tye-Din, Robert P. Anderson

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Improved blood tests assessing the functional status of rare gluten-specific CD4+ T cells are needed to effectively monitor experimental therapies for coeliac disease (CD). Our aim was to develop a simple, but highly sensitive cytokine release assay

Externí odkaz: https://doaj.org/article/44d464c9335848cca3a691f2d2a3caa2

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Pyrethrum and the Second World War: Recontextualising DDT in the Narrative of Wartime Insect Control

Autor: Sabine Clarke, Richard J. E. Brown

Publikováno v: HoST - Journal of History of Science and Technology. 16:89-112

Historians have long recognised that DDT’s fame began with extraordinary propaganda late in the Second World War, yet heroic narratives that centre the chemical still shape historical understanding. Two false assumptions inform much of the existing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f9d332b35d4269ca0bc508618ef3d38
https://doi.org/10.2478/host-2022-0017

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Akademický článek

ON INFLUENCE OF THE UNDERGROUND NUCLEAR EXPLOSIONS CRYSTAL AND KRATON-3 ON RADIOLOGICAL SITUATION IN THE NEAREST SETTLEMENTS

Autor: V. P. Ramzaev, I. G. Travnikova, L. N. Basalaeva, G. Ya. Bruk, V. Yu. Golikov, A. S. Mishin, J. E. Brown, P. Strand

Publikováno v: Радиационная гигиена, Vol 1, Iss 2, Pp 14-19 (2017)

The results of radiological investigations (in 2001-2002) conducted near sites of the underground nuclear explosions Crystal and Kraton-3 in the Republic of Sakha (Yakutia) are presented. The sum of the current effective internal doses from 137Cs and

Externí odkaz: https://doaj.org/article/27cfcb50250544c5adc4734ac6b787ba

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Forecasting Extreme Ultraviolet Thermospheric Drivers from Solar Imaging using Deep Learning

Autor: Edward J. E. Brown, Filip Svoboda, Nigel P. Meredith

The thermosphere is heated by incident extreme ultraviolet (EUV) radiation from the Sun. Accurately forecasting this driver of thermospheric density is of paramount importance to spacecraft operations, such as collision avoidance, in an increasingly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2094f7124eed6bd700540bc281c8eab9
https://doi.org/10.22541/essoar.168500301.13213549/v1

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Assessment of non-directed computer-use behaviours in the home can indicate early cognitive impairment: A proof of principle longitudinal study

Autor: Gemma Stringer, Samuel Couth, Hein Heuvelman, Christopher Bull, Ann Gledson, John Keane, Paul Rayson, Alistair Sutcliffe, Peter Harvey Sawyer, Xiao-Jun Zeng, Daniela Montaldi, Laura J. E. Brown, Iracema Leroi

Publikováno v: Aging & Mental Health. 27:193-202

Objectives: Computer-use behaviours can provide useful information about an individual’s cognitive and functional abilities. However, little research has evaluated unaided and non-directed home computer-use. In this proof of principle study, we exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c89ee1fa6301d059429a24912502a7
https://doi.org/10.1080/13607863.2022.2036946

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‘It’s just incredible the difference it has made’: family carers’ experiences of a specialist Lewy body dementia Admiral Nurse service

Autor: Laura J E Brown, Zena Aldridge, Amy Pepper, Iracema Leroi, Karen Harrison Dening

Publikováno v: Brown, L J E, Aldridge, Z, Pepper, A, Leroi, I & Harrison Dening, K 2022, ' It’s just incredible the difference it has made’: Family carers’ experiences of a specialist Lewy body dementia Admiral Nurse service ', Age and Ageing, vol. 51, no. 10, afac207 . https://doi.org/10.1093/ageing/afac207

Background Lewy body dementia (LBD) is characterised by a complex array of symptoms. Being a family carer of someone with LBD can be challenging, and is associated with high levels of stress, depression and anxiety. Admiral Nursing services support f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7820b1649344fc588c51ef7d892edd7
https://doi.org/10.1093/ageing/afac207

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