Zobrazeno 1 - 10
of 402
pro vyhledávání: '"J Du Bois"'
Autor:
Mengyuan Xu, Torben Neelands, Alexander S Powers, Yan Liu, Steven D Miller, Grigore D Pintilie, J Du Bois, Ron O Dror, Wah Chiu, Merritt Maduke
Publikováno v:
eLife, Vol 12 (2024)
CLC-2 is a voltage-gated chloride channel that contributes to electrical excitability and ion homeostasis in many different tissues. Among the nine mammalian CLC homologs, CLC-2 is uniquely activated by hyperpolarization, rather than depolarization,
Externí odkaz:
https://doaj.org/article/ff8936247b544286b1d7a57aab5b1a3c
Autor:
Anna V. Elleman, Gabrielle Devienne, Christopher D. Makinson, Allison L. Haynes, John R. Huguenard, J. Du Bois
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Photocaged molecules have advantages in terms of temporal and spatial control compared to conventional pharmacological compounds. The authors present a synthetic saxitoxin derivative affixed to a photocleavable group for precise modulation of Na chan
Externí odkaz:
https://doaj.org/article/bf380589f814439eb42a94b2247df74e
Autor:
Anna V. Elleman, Gabrielle Devienne, Christopher D. Makinson, Allison L. Haynes, John R. Huguenard, J. Du Bois
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/449049f0a23341bca426eafa669d5b54
Autor:
Hassan Pajouhesh, Anton Delwig, Jacob T. Beckley, Sheri Klas, Dennis Monteleone, Xiang Zhou, George Luu, J. Du Bois, John C. Hunter, John V. Mulcahy
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1763-1768
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::102cff2de10cc253178902476de0b6ce
https://doi.org/10.1021/acsmedchemlett.2c00378
https://doi.org/10.1021/acsmedchemlett.2c00378
Autor:
Apurva A. Oak, Tifany Chu, Pattareeya Yottasan, Parth D. Chhetri, Jie Zhu, J. Du Bois, Onur Cil
Publikováno v:
Molecular Pharmacology. 102:106-115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091ca4eca9231b65c879a824b9281a4e
https://doi.org/10.1124/molpharm.122.000542
https://doi.org/10.1124/molpharm.122.000542
Akademický článek
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Autor:
Husniye Kantarci, Pablo D. Elvira, Arun P. Thottumkara, Manasi Iyer, Lauren J. Donovan, Micaela Quinn Dugan, Nicholas Ambiel, Emma M. O’Connell, Alejandro Granados, Hong Zeng, Nay L. Saw, Amanda Brosius Lutz, Steven A. Sloan, Erin E. Gray, Khanh V. Tran, Aditi Vichare, Ashley K. Yeh, Alexandra E. Münch, Max Huber, Aditi Agrawal, Maurizio Morri, Mehrdad Shamloo, Thomas Anthony Anderson, Vivianne L. Tawfik, J. Du Bois, J. Bradley Zuchero
SUMMARYExcitability—the ability to fire action potentials—is a signature feature of neurons. How neurons become excitable during development, and whether excitability is an intrinsic property of neurons or requires signaling from glial cells, rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c649b8270dfe1ec4fc02b52106804825
https://doi.org/10.2139/ssrn.4405268
https://doi.org/10.2139/ssrn.4405268
Autor:
Zhou Chen, Sandra Zakrzewska, Holly S. Hajare, Aurora Alvarez-Buylla, Fayal Abderemane-Ali, Maximiliana Bogan, Dave Ramirez, Lauren A. O’Connell, J. Du Bois, Daniel L. Minor
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 44
American bullfrog ( Rana castesbeiana ) saxiphilin ( Rc Sxph) is a high-affinity “toxin sponge” protein thought to prevent intoxication by saxitoxin (STX), a lethal bis-guanidinium neurotoxin that causes paralytic shellfish poisoning (PSP) by blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025c106450d858e7d469c2c41b558667
https://pubmed.ncbi.nlm.nih.gov/36279441
https://pubmed.ncbi.nlm.nih.gov/36279441
Akademický článek
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Publikováno v:
ACS Catalysis. 11:10479-10486
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6adbfab416e672f3db05feedaf57b067
https://doi.org/10.1021/acscatal.1c02593
https://doi.org/10.1021/acscatal.1c02593