Mass spectrometry provides accurate characterization of two genetic marker types in Bacillus anthracis

Autor: Matthew N. Van Ert, Steven A. Hofstadler, Yun Jiang, Joseph D. Busch, David M. Wagner, Jared J. Drader, David J. Ecker, James C. Hannis, Lynn Y. Huynh, James M. Schupp, Tatum S. Simonson, Paul Keim

Publikováno v: BioTechniques, Vol 37, Iss 4, Pp 642-651 (2004)

Epidemiological and forensic analyses of bioterrorism events involving Bacillus anthracis could be improved if both variable number tandem repeats (VNTRs) and single nucleotide polymorphisms (SNPs) could be combined on a single analysis platform. Her

Externí odkaz: https://doaj.org/article/aaf2faa25f674507935a47f0e3190f9a

Fast, sensitive point of care electrochemical molecular system for point mutation and select agent detection

Autor: J. A. MacLeod, Dan Wang, W. C. Dicke, Jared J. Drader, A. C. Nemeth, S. Manalili Wheeler, James C. Hannis, G. B. Collier

Publikováno v: Lab on a Chip. 16:2513-2520

Point of care molecular diagnostics benefits from a portable battery-operated device capable of performing a fast turnaround using reliable inexpensive cartridges. We describe a prototype device for performing a molecular diagnostics test for clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a5e458fda4fbb10a374434e2407f82
https://doi.org/10.1039/c5lc01532d

Usefulness of multilocus polymerase chain reaction followed by electrospray ionization mass spectrometry to identify a diverse panel of bacterial isolates

Autor: Larry B. Blyn, Karen Studarus, Vanessa Harpin, Ranga Sampath, Heather E. Matthews, Sharon L. Abbott, Gerald B. Howe, Thomas A. Hall, Jared J. Drader, Karl Rudnick, Mark W. Eshoo, Chris A. Whitehouse, David Moore, Steve Hofstadler, J. Michael Janda, Carson Baldwin

Publikováno v: Diagnostic Microbiology and Infectious Disease. 63:403-408

Polymerase chain reaction electrospray ionization mass spectrometry (PCR/ESI-MS) was tested for its ability to accurately identify a blinded panel of 156 diverse bacterial isolates, mostly human and/or animal pathogens. Here, 142/156 (91%) isolates w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5c9ef4b4970283fcfe137085b3b75d
https://doi.org/10.1016/j.diagmicrobio.2008.12.012

The Ibis T5000 Universal Biosensor: An Automated Platform for Pathogen Identification and Strain Typing

Autor: Mark W. Eshoo, Duane J. Knize, Fred Hajjar, Kristin A. Sannes-Lowery, Maria Tobarmosquera, Karl Rudnick, Sheri Manalili, Yun Jiang, Demetrius J. Walcott, James C. Hannis, Jared J. Drader, Feng Li, Christian Massire, Vanessa Harpin, Amy Schink, Jose R. Gutierrez, Brian Libby, Steven A. Hofstadler, Lawrence B. Blyn, Harold B. Levene, David Robbins, Lendell L. Cummins, Rachael Melton, Raymond Ranken, Vivek Samant, Rangarajan Sampath, Michael Pear, David J. Ecker, Thomas A. Hall, Abel Gutierrez, Neill White, Christina Ivy, Joseph A. Ecker

Publikováno v: JALA: Journal of the Association for Laboratory Automation. 11:341-351

We describe a new approach to the sensitive and specific identification of bacteria, viruses, fungi, and protozoa based on broad-range PCR and high-performance mass spectrometry. The Ibis T5000 is based on technology developed for the Department of D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6ca66cd8e716dd08fc5062db27eff5e
https://doi.org/10.1016/j.jala.2006.09.001

Rapid Identification of Emerging Pathogens: Coronavirus

Autor: Jared J. Drader, Thomas A. Hall, Mark W. Eshoo, Raymond Ranken, Rangarajan Sampath, Christian Massire, Richard H. Griffey, Michael J. Buchmeier, Vivek Samant, Stanley T. Crooke, Lawrence B. Blyn, Yun Jiang, Harold M. Levene, Steven A. Hofstadler, Benjamin W. Neuman, David J. Ecker, James C. Hannis, John Mcneil, Patina M. Harrell

Publikováno v: Emerging Infectious Diseases
Scopus-Elsevier
Emerging Infectious Diseases, Vol 11, Iss 3, Pp 373-379 (2005)
Sampath, R; Hofstadler, SA; Blyn, LB; Eshoo, MW; Hall, TA; Massire, C; et al.(2005). Rapid identification of emerging pathogens: Coronavirus. Emerging Infectious Diseases, 11(3), 373-379. doi: 10.3201/eid1103.040629. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0p4142mf

New surveillance approach can analyze >900 polymerase chain reactions per day.
We describe a new approach for infectious disease surveillance that facilitates rapid identification of known and emerging pathogens. The process uses broad-range pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a773064ddc79ac2c713dcfb5910f46
http://europepmc.org/articles/PMC3298233