Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J Douchamps"'
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 31(3)
The aim of this study was to compare the efficacy and safety of amikacin given either as single injection or as two injections within 12-h interval in the treatment of severe gram-negative infections in elderly patients. Thirty-nine non-selected cons
Publikováno v:
British journal of clinical pharmacology. 31(1)
1. Almitrine bismesylate displays wide inter-subject variation in peak plasma concentrations and can induce peripheral polyneuropathy. 2. The phenotyped volunteer panel approach was used to examine whether almitrine oxidation displayed a genetic poly
Autor:
J Douchamps, Eric Delcourt, André Herchuelz, Claire Dulcire, Michèle Juvent, Dirk d'hooge, Willy Kostucki
Publikováno v:
Clinical neuropharmacology. 13(1)
In a double-blind, placebo-controlled, crossover study, the effects of therapeutic doses of the new tricyclic antidepressant tianeptine on cardiovascular function were closely monitored in 21 healthy volunteers during a 2-week treatment period. Blood
Publikováno v:
European Journal of Pharmacology. 183:2383
Publikováno v:
European Journal of Clinical Pharmacology. 31:29-34
The pharmacodynamic effects of torasemide, a new potent loop diuretic, were compared with those of furosemide in a double blind controlled study in 18 hypertensive patients with oedema of various origins. Given orally for 5 days, torasemide was clini
Publikováno v:
British Journal of Clinical Pharmacology. 12:801-805
1 The pharmacokinetics of cefuroxime have been investigated in 18 patients at least 70 years old. The drug was given either by continuous infusion (7 cases) or by multiple injections (11 cases) for 3 to 11 days (mean duration: 7 days). 2 The unchange
Publikováno v:
European Journal of Clinical Pharmacology. 24:671-673
Oxametacin, a new non steroidal anti-inflammatory compound, with analgesic, antipyretic and anti-inflammatory properties comparable to those of indomethacin, has been claimed to be effective in treatment of acute attacks of gout. The present study co
Publikováno v:
European journal of clinical pharmacology. 35(5)
We have studied the pharmacokinetics of oxybutynin (Ditropan) after single oral (5 mg) and intravenous administration (1 and 5 mg), and after repeated oral administration in healthy volunteers. Oxybutynin was rapidly absorbed, maximum plasma concentr
Publikováno v:
European journal of clinical pharmacology.
The effects of torasemide, a new potent loop diuretic, on renin release, water and sodium excretion were investigated in young healthy volunteers before and after 3 days of treatment with indomethacin. Torasemide 20 mg i.v. induced a rapid and biphas
Publikováno v:
Arzneimittel-Forschung. 38(1A)
The pharmacodynamics of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea), a new potent loop diuretic, were compared to those of furosemide in a double-blind controlled study in 18 patients with oedema of various origin.