Zobrazeno 1 - 10
of 260
pro vyhledávání: '"J Dornand"'
Publikováno v:
European Journal of Neuroscience. 10:3107-3114
We studied, using organotypic hippocampal slices in culture, the role of pro-inflammatory cytokines, oxygen radicals and nitric oxide in neuronal death induced either by endotoxic insult [interferon (IFN) gamma, 24 h followed by lipopolysaccharide, 2
Autor:
F Ouaaz, Mossalayi, Michel Arock, B Dugas, Nathalie Dugas, A Calenda, Patrice Debré, P.-A. Becherel, A Leotard, F Mentz, J Dornand
Publikováno v:
Blood. 88:3528-3534
All trans retinoic acid and vitamin D3 derivatives are well known for their antileukemic activity, while the precise mechanism of this effect remains to be clarified. Using human leukemic U937 and THP-1 promonocytic cell lines, we analyzed the effect
Publikováno v:
The Journal of Immunology. 155:181-189
We reassessed the involvement of Bordetella pertussis toxin (PTX)-sensitive proteins in the IL-1 signaling pathway on the responses induced by IL-1 on the murine thymoma cell line EL4 6.1. We demonstrate that the ADP-ribosyltransferase activity of PT
Publikováno v:
Neuroreport. 7(6)
We studied the production of tumor necrosis factor alpha (TNF alpha) and interleukin-6 (IL-6) 2 and 7 days following status epilepticus (SE), induced in rats by intra-amygdala injection of kainate. At day 2 the release of both cytokines by hippocampa
Publikováno v:
Vitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7206cfa66c2f5a5ca84b270efe00f5ff
https://doi.org/10.1515/9783110882513-151
https://doi.org/10.1515/9783110882513-151
Autor:
Stanislav Vybíral, Joachim Roth, J. Kamínková, Eugen Zeisberger, D. Pospíšilová, J. Dornand, Ladislav Janský
Publikováno v:
Thermal Balance in Health and Disease ISBN: 9783034874311
Fever induced by lipopolysaccharide (LPS) causes release of endogenous pyrogens into circulation. Since cytokines have a capacity to induce fever, when injected peripherally or centrally, the view prevails that they act as endogenous pyrogens (8). It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ce71f4b56ade7d423bb932bf64612f
https://doi.org/10.1007/978-3-0348-7429-8_48
https://doi.org/10.1007/978-3-0348-7429-8_48
Autor:
J. Dornand, M. Gerbert
Publikováno v:
Oxidative Stress, Cell Activation and Viral Infection ISBN: 9783034874267
We have shown that free radical scavengers inhibit IL2 synthesis and that reactive oxygen species are induced upon T cell activation. Because of their physiological relevance, we concentrated our study on lipoxygenase (LO) inhibitors. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f5c8f9a2e8b19aa34051029e16dac6
https://doi.org/10.1007/978-3-0348-7424-3_22
https://doi.org/10.1007/978-3-0348-7424-3_22
Publikováno v:
Oxidative Stress, Cell Activation and Viral Infection ISBN: 9783034874267
We submitted cultured human umbilical vein endothelial cells to 5h hypoxia followed by 20 min to 24h reoxygenation. This resulted in an increased adhesion of human resting neutrophils to monolayers with two peaks after 20 min and 4h reoxygenation. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae555a1078d330b1cc5fc7193a4d755
https://doi.org/10.1007/978-3-0348-7424-3_8
https://doi.org/10.1007/978-3-0348-7424-3_8
Publikováno v:
Journal of cellular physiology. 154(1)
Transforming growth factor beta (TGF-beta) is a cytokine with immunoregulatory properties that acts negatively on T lymphocyte proliferation. However, with the EL 4-6.1 variant of the murine thymoma EL 4 activated with phorbol ester and/or interleuki
Autor:
J, Dornand, M, Gerber
Publikováno v:
Journal of lipid mediators. 4(1)
We investigated the mechanisms by which lipoxygenase (LO) inhibitors decrease interleukin-2 (IL-2) production in Jurkat cells. We demonstrate that the inhibition, linked to blockade of the [Ca2+]i rise involving T cell receptor (TCR) triggering, resu