Zobrazeno 1 - 10
of 104
pro vyhledávání: '"J Donald, Ostrow"'
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 189-194 (2000)
Methods to study growth of gallstones in the laboratory have not been reported. We here present such a method. Human cholesterol gallstones were harvested from patients with multiple nearly identical stones. The gallstones were washed and added to su
Externí odkaz:
https://doaj.org/article/03ffb371fb284b4d853bc16ff9986c13
Autor:
Silvia Gazzin, Andrea Lorena Berengeno, Nathalie Strazielle, Francesco Fazzari, Alan Raseni, J Donald Ostrow, Richard Wennberg, Jean-François Ghersi-Egea, Claudio Tiribelli
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16165 (2011)
Accumulation of unconjugated bilirubin (UCB) in the brain causes bilirubin encephalopathy. Pgp (ABCb1) and Mrp1 (ABCc1), highly expressed in the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB) respectively, may modulate the ac
Externí odkaz:
https://doaj.org/article/95b2c903613e41fd8be95c7ebc6388ee
Autor:
Gary Schoch, George B. McDonald, Ashley T. Evans, J. Donald Ostrow, Jeannine S. McCune, Ted Gooley
Publikováno v:
The Lancet. Haematology. 3(11)
Gilbert's syndrome is a common inherited disorder of bilirubin metabolism, characterised by mild, unconjugated hyperbilirubinaemia. However, the effect of Gilbert's syndrome on the disposition of some drugs can lead to unexpected toxicity. We tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7d1ffe1b2cf6fb09fe5fe57a10eaf6
https://pubmed.ncbi.nlm.nih.gov/27968817
https://pubmed.ncbi.nlm.nih.gov/27968817
Autor:
Claudio Tiribelli, Raymond T. Doty, Zhantao Yang, Ann Smith, John D. Philips, Janis L. Abkowitz, J. Donald Ostrow, Pablo J. Giraudi
Publikováno v:
Journal of Biological Chemistry. 285:28874-28882
The feline leukemia virus subgroup C receptor (FLVCR) is a heme export protein that is required for proerythroblast survival and facilitates macrophage heme iron recycling. However, its mechanism of heme export and substrate specificity are uncharact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6b7a1d314aa392d85d0b66734ee071
https://doi.org/10.1074/jbc.m110.119131
https://doi.org/10.1074/jbc.m110.119131
Publikováno v:
LaboratoriumsMedizin. 34:15-27
ZusammenfassungHintergrund:Die Konzentration des Gesamtbilirubins (BT) in Serum oder Plasma war lange Zeit die klinische Standard-Laboratoriumsuntersuchung für die Bewertung eines Neugeborenenikterus, obwohl Studien zeigten, dass keine enge Korrelat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eaac2c0528732d5376c81efcab0a945
https://doi.org/10.1515/jlm.2010.010
https://doi.org/10.1515/jlm.2010.010
Autor:
J. Donald Ostrow, Claudio Tiribelli, Anja M. Hafkamp, Maarten Sinaasappel, Henkjan J. Verkade, Lorella Pascolo, Rick Havinga
Publikováno v:
Pediatric Research, 59(4 Pt 1), 506-512. Lippincott Williams & Wilkins
Pediatric Research, 59(4), 506-512. Nature Publishing Group
Pediatric Research, 59(4), 506-512. Nature Publishing Group
Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a53ac8877ba09651fcfc32e88d1f08
https://doi.org/10.1203/01.pdr.0000203180.79636.98
https://doi.org/10.1203/01.pdr.0000203180.79636.98
Autor:
J. Donald Ostrow, Claudio Tiribelli
Publikováno v:
Journal of Hepatology. 43:156-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf6b4c8d5692d2cd7feda1c1d8bae79
https://doi.org/10.1016/j.jhep.2005.04.003
https://doi.org/10.1016/j.jhep.2005.04.003
Publikováno v:
Biochemical Journal. 383:335-341
Results of previous studies have suggested that UCB (unconjugated bilirubin) may be transported by MRP1/Mrp1 (multidrug-resistance-associated protein 1). To test this hypothesis directly, [3H]UCB transport was assessed in plasma-membrane vesicles fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b5a519793b719980f2ccf0f15b00c5
https://doi.org/10.1042/bj20040599
https://doi.org/10.1042/bj20040599
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Unconjugated bilirubin (UCB), at slightly elevated unbound concentrations, is toxic to astrocytes and neurons, damaging mitochondria (causing impaired energy metabolism and apoptosis) and plasma membranes (causing oxidative damage and disrupting tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae3c766a2ebd49f571e7e6946f5e705
https://doi.org/10.1016/j.molmed.2003.12.003
https://doi.org/10.1016/j.molmed.2003.12.003
Autor:
Dean Cekic, Cristina Bellarosa, Lorella Pascolo, Claudio Tiribelli, J. Donald Ostrow, Maria Victoria Garcia-Mediavilla, Igino Rigato
Publikováno v:
Biochemical and Biophysical Research Communications. 311:891-896
Earlier studies suggest that Mrp1 may mediate ATP-dependent cellular extrusion of unconjugated bilirubin (UCB). We studied the serial responses of expression of Mrp1 mRNA and protein in rats with increased bilirubin production due to hemolysis induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6791df49494410f2ec302b8546c84534
https://doi.org/10.1016/j.bbrc.2003.10.081
https://doi.org/10.1016/j.bbrc.2003.10.081