Zobrazeno 1 - 10 of 17 pro vyhledávání: '"J Des Parkin"'
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Akademický článek
The collαgen III fibril has a 'flexi-rod' structure of flexible sequences interspersed with rigid bioactive domains including two with hemostatic roles.
Autor: J Des Parkin, James D San Antonio, Anton V Persikov, Hayat Dagher, Raymond Dalgleish, Shane T Jensen, Xavier Jeunemaitre, Judy Savige
Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0175582 (2017)
Collagen III is critical to the integrity of blood vessels and distensible organs, and in hemostasis. Examination of the human collagen III interactome reveals a nearly identical structural arrangement and charge distribution pattern as for collagen
Externí odkaz: https://doaj.org/article/958b23c874db42d29f3955a5ae78635a
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The collαgen III fibril has a 'flexi-rod' structure of flexible sequences interspersed with rigid bioactive domains including two with hemostatic roles
Autor: Raymond Dalgleish, Hayat Dagher, J. Des Parkin, Shane T. Jensen, Judy Savige, Anton V. Persikov, James D. San Antonio, Xavier Jeunemaitre
Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0175582 (2017)
PLoS ONE
Collagen III is critical to the integrity of blood vessels and distensible organs, and in hemostasis. Examination of the human collagen III interactome reveals a nearly identical structural arrangement and charge distribution pattern as for collagen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588700cea11f0dc2e6efeb88b90ea061
http://europepmc.org/articles/PMC5509119?pdf=render
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3
Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes
Autor: J. Des Parkin, Shane T. Jensen, Billy G. Hudson, Judy Savige, Vadim Pedchenko, James D. San Antonio
Publikováno v: Human Mutation. 32:127-143
Collagen IV is the major protein found in basement membranes. It comprises three heterotrimers (α1α1α2, α3α4α5, and α5α5α6) that form distinct networks, and are responsible for membrane strength and integrity.We constructed linear maps of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28829be8ff0c5bfe679387e6d636f14
https://doi.org/10.1002/humu.21401
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4
Lupus anticoagulant in the elderly may be associated with both quinine and quinidine usage
Autor: Margaret R. Bird, Kamal Ibrahim, J. Des Parkin, Russell R C Buchanan, Anthony I. O’Neill
Publikováno v: Pathology. 27:136-139
Thirty-one patients aged over 60 yrs and with lupus anticoagulant (LA) were reviewed for their drug intake. Twenty-three (73%) were taking cinchona alkaloids, 10 (32%) quinine for night cramps, 11 (35%) quinidine for cardiac arrhythmia and 2 (6%) wer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18521b3a8d46f0d67a2d1cef9e4954c1
https://doi.org/10.1080/00313029500169742
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6
Measurement of iohexol by capillary electrophoresis: minimizing practical problems encountered
Autor: Sujiva Ratnaike, George Jerums, Christine A Houlihan, J Des Parkin, Margaret A Jenkins
Publikováno v: Annals of clinical biochemistry. 37
Iohexol is a non-ionic contrast agent, which has been widely described in recent literature as an accurate marker for the measurement of glomerular filtration rate (GFR). Our aim was to establish a capillary electrophoresis assay, based on a previous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f6f37abd1afebe97f9fb7a1f98a672
https://pubmed.ncbi.nlm.nih.gov/10902871
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7
A novel detection method for heteroduplex DNA using carbodiimide-induced interrupted primer extension
Autor: Tania Tabone, Richard G.H. Cotton, Ninan Mathew, J. Des Parkin, Judy Savige
Publikováno v: Journal of Nucleic Acids Investigation. 1:5
Direct sequencing may be problematic in demonstrating mutations where inherited disease results from multiple different heterozygous variants in large genes. We describe here a novel mutation screening method based on the ability of carbodiimide to b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0fbf44c504394abd1d912d61fe55489
https://doi.org/10.4081/jnai.2010.1577
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8
Automation of the Kaolin Clotting Time
Autor: J. Des Parkin, Kamal Ibrahim, Anthony I. O’Neill
Publikováno v: Pathology. 24(1)
An automated Kaolin Clotting Time (KCT) has been developed to simplify screening for the Lupus Anticoagulant (LA). The assay is performed on the ACL300 Research coagulation analyser, but may be modified for other centrifugal analysers. Automation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cfefab5eb2ef006dacd51bb61798c5
https://pubmed.ncbi.nlm.nih.gov/1579364
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10
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