Zobrazeno 1 - 10
of 193
pro vyhledávání: '"J David Robertson"'
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179360 (2017)
Estrogen-mimicking chemicals, such as cadmium, may be associated with increased susceptibility to hormone-dependent cancers, though supporting data are sparse, particularly for endometrial cancer. The Health and Environmental Exposure Research (HEER)
Externí odkaz:
https://doaj.org/article/0bcb92fb22bb4e16b3dda240d64018a2
Autor:
David Rotsch, Tom Brossard, Saadia Bihmidine, Weijiang Ying, Vikram Gaddam, Michael Harmata, J David Robertson, Michael Swyers, Silvia S Jurisson, David M Braun
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128989 (2015)
Sugars produced from photosynthesis in leaves are transported through the phloem tissues within veins and delivered to non-photosynthetic organs, such as roots, stems, flowers, and seeds, to support their growth and/or storage of carbohydrates. Howev
Externí odkaz:
https://doaj.org/article/64a569a7497743b2a72f76e7efd5db4f
Autor:
Kurt Warnhoff, John T Murphy, Sandeep Kumar, Daniel L Schneider, Michelle Peterson, Simon Hsu, James Guthrie, J David Robertson, Kerry Kornfeld
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004703 (2014)
The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high
Externí odkaz:
https://doaj.org/article/e9aeb6e26dc3421ab66c058585e8c3b6
Autor:
Hyun Cheol Roh, Sara Collier, Krupa Deshmukh, James Guthrie, J David Robertson, Kerry Kornfeld
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003522 (2013)
Zinc is an essential metal involved in a wide range of biological processes, and aberrant zinc metabolism is implicated in human diseases. The gastrointestinal tract of animals is a critical site of zinc metabolism that is responsible for dietary zin
Externí odkaz:
https://doaj.org/article/e39dadd1af1d42ce960bfed63adb7ef3
Autor:
Mark F McLaughlin, Jonathan Woodward, Rose A Boll, Jonathan S Wall, Adam J Rondinone, Stephen J Kennel, Saed Mirzadeh, J David Robertson
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54531 (2013)
Targeted radiotherapies maximize cytotoxicty to cancer cells. In vivo α-generator targeted radiotherapies can deliver multiple α particles to a receptor site dramatically amplifying the radiation dose delivered to the target. The major challenge wi
Externí odkaz:
https://doaj.org/article/1a3a1583aa87460787fc214aaf7959c6
Autor:
Rachel A Kudgus, Annamaria Szabolcs, Jameel Ahmad Khan, Chad A Walden, Joel M Reid, J David Robertson, Resham Bhattacharya, Priyabrata Mukherjee
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57522 (2013)
Pancreatic cancer is one of the deadliest of all human malignancies with limited options for therapy. Here, we report the development of an optimized targeted drug delivery system to inhibit advanced stage pancreatic tumor growth in an orthotopic mou
Externí odkaz:
https://doaj.org/article/f606ebcc2fe84b94a13638e2c5830d9a
Autor:
John T Murphy, Janelle J Bruinsma, Daniel L Schneider, Sara Collier, James Guthrie, Asif Chinwalla, J David Robertson, Elaine R Mardis, Kerry Kornfeld
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1002013 (2011)
Zinc is an essential trace element involved in a wide range of biological processes and human diseases. Zinc excess is deleterious, and animals require mechanisms to protect against zinc toxicity. To identify genes that modulate zinc tolerance, we pe
Externí odkaz:
https://doaj.org/article/96865767aa4c4f5fb2a6ca7d7bba7383
Autor:
Jameel Ahmad Khan, Rachel A Kudgus, Annamaria Szabolcs, Shamit Dutta, Enfeng Wang, Sheng Cao, Geoffry L Curran, Vijay Shah, Steven Curley, Debabrata Mukhopadhyay, J David Robertson, Resham Bhattacharya, Priyabrata Mukherjee
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20347 (2011)
Pancreatic cancer is the fourth leading cause of cancer related deaths in America. Monoclonal antibodies are a viable treatment option for inhibiting cancer growth. Tumor specific drug delivery could be achieved utilizing these monoclonal antibodies
Externí odkaz:
https://doaj.org/article/497c8f08d43c4e7ab533a0da035e895e
Autor:
Rochelle R Arvizo, Oscar R Miranda, Daniel F Moyano, Chad A Walden, Karuna Giri, Resham Bhattacharya, J David Robertson, Vincent M Rotello, Joel M Reid, Priyabrata Mukherjee
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24374 (2011)
Inorganic nanoparticles provide promising tools for biomedical applications including detection, diagnosis and therapy. While surface properties such as charge are expected to play an important role in their in vivo behavior, very little is known how
Externí odkaz:
https://doaj.org/article/9b89929c3e4f42c6b69880f5c7d92e6d
Publikováno v:
Nuclear Science and Engineering. :1-9