Zobrazeno 1 - 10
of 75
pro vyhledávání: '"J David Port"'
Autor:
Christopher M O'Connor, Mona Fiuzat, Peter E Carson, Inder S Anand, Jonathan F Plehn, Stephen S Gottlieb, Marc A Silver, JoAnn Lindenfeld, Alan B Miller, Michel White, Ryan Walsh, Penny Nelson, Allen Medway, Gordon Davis, Alastair D Robertson, J David Port, James Carr, Guinevere A Murphy, Laura C Lazzeroni, William T Abraham, Stephen B Liggett, Michael R Bristow
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44324 (2012)
Pharmacogenetics involves complex interactions of gene products affecting pharmacodynamics and pharmacokinetics, but there is little information on the interaction of multiple genetic modifiers of drug response. Bucindolol is a β-blocker/sympatholyt
Externí odkaz:
https://doaj.org/article/cd47e15ce88a411b9af992526484b8c4
Autor:
Philip D. Tatman, David P. Kao, Kathryn C. Chatfield, Ian A. Carroll, Jessica A. Wagner, Eric R. Jonas, Carmen C. Sucharov, J. David Port, Brian D. Lowes, Wayne A. Minobe, Sophia P. Huebler, Anis Karimpour-Fard, Erin M. Rodriguez, Stephen B. Liggett, Michael R. Bristow
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
We investigated the extent, biologic characterization, phenotypic specificity, and possible regulation of a β1-adrenergic receptor–linked (β1-AR–linked) gene signaling network (β1-GSN) involved in left ventricular (LV) eccentric pathologic rem
Externí odkaz:
https://doaj.org/article/cc7c56d0fed841659469accaddf4f47a
Publikováno v:
JACC: Basic to Translational Science, Vol 7, Iss 9, Pp 956-969 (2022)
Summary: Cardiovascular disease (CVD) remains the largest cause of mortality worldwide. The development of new effective therapeutics is a major unmet need. The current review focuses broadly on the concept of nucleic acid (NA)–based therapies, con
Externí odkaz:
https://doaj.org/article/f91744faf17b46dea4fb7a69844eb4af
Autor:
J. David Port
Publikováno v:
JACC: Basic to Translational Science. 5:1070-1072
Publikováno v:
Heart Failure: a Companion to Braunwald's Heart Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::402ec4d056c9d5f64cb606f1bef1bb7a
https://doi.org/10.1016/b978-0-323-60987-6.00006-5
https://doi.org/10.1016/b978-0-323-60987-6.00006-5
Autor:
E. Dale Abel, Luigi Adamo, Shah R. Ali, Larry A. Allen, George L. Bakris, Gerald S. Bloomfield, Robert O. Bonow, Biykem Bozkurt, Michael R. Bristow, Angela L. Brown, Heiko Bugger, John C. Burnett, Javed Butler, John D. Carroll, Adam Castaño, Anna Marie Chang, Jay N. Cohn, Wilson S. Colucci, Louis J. Dell’Italia, Anita Deswal, Adam D. DeVore, Abhinav Diwan, Hilary M. DuBrock, Shannon M. Dunlay, Nina Dzhoyashvili, Gregory A. Ewald, Justin A. Ezekowitz, James C. Fang, Savitri Fedson, Matthew J. Feinstein, G. Michael Felker, John D. Ferguson, Victor A. Ferrari, Carlos M. Ferrario, James D. Flaherty, John S. Floras, Viorel G. Florea, Hanna K. Gaggin, Barry Greenberg, Joshua M. Hare, Adrian F. Hernandez, Joseph A. Hill, Nasrien E. Ibrahim, James L. Januzzi, Susan M. Joseph, Daniel P. Judge, Andrew M. Kahn, Andreas P. Kalogeropoulos, David A. Kass, John Keaney, Ahsan A. Khan, Paul J. Kim, Jon A. Kobashigawa, Evan P. Kransdorf, Eric V. Krieger, Nicholas T. Lam, Daniel J. Lenihan, Gregory Y.H. Lip, Chris T. Longenecker, W. Robb MacLellan, Douglas L. Mann, Ali J. Marian, Daniel D. Matlock, Mathew S. Maurer, Dennis M. McNamara, Robert J. Mentz, Marco Metra, Carmelo A. Milano, Arunima Misra, Joshua D. Mitchell, Alan R. Morrison, Adam Nabeebaccus, Kenta Nakamura, Jose Nativi-Nicolau, Doan T.M. Ngo, Kelsie E. Oatmen, Peter S. Pang, Lampros Papadimitriou, Walter J. Paulus, Tamar S. Polonsky, J. David Port, Florian Rader, Loheetha Ragupathi, Margaret M. Redfield, Michael W. Rich, Joseph G. Rogers, John J. Ryan, Hesham A. Sadek, Can Martin Sag, Ashley A. Sapp, Douglas B. Sawyer, P. Christian Schulze, Ajay M. Shah, Eduard Shantsila, Jagmeet P. Singh, Albert J. Sinusas, Karen Sliwa, Francis G. Spinale, Simon Stewart, Carmen Sucharov, Martin St. John Sutton, Aaron L. Sverdlov, Michael J. Toth, Anne Marie Valente, Loek van Heerebeek, Jasmina Varagic, Ronald G. Victor, Ian Webb, Adam R. Wende, David Whellan, Dominik M. Wiktor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda3f3f2170fa669e86863d27bc94b33
https://doi.org/10.1016/b978-0-323-60987-6.01002-4
https://doi.org/10.1016/b978-0-323-60987-6.01002-4
Autor:
Michael R. Bristow, J. David Port
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 630-632 (2016)
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 630-632 (2016)
Corresponding Author
Autor:
Jeffrey A. Borgia, Rama Kamesh Bikkavilli, Sreedevi Avasarala, Michelle Van Scoyk, J. David Port, Melissa R. Pergande, Manoj Kumar Karuppusamy Rathinam, James DeGregori, Robert A. Winn, Xiangmin Zhao, Wei Zhang, Sereke Zerayesus
Publikováno v:
The Journal of Biological Chemistry
Background: PRMT1 is up-regulated in lung cancer. Results: PRMT1 is a novel regulator of EMT and Twist1 is a new PRMT1 substrate. Conclusion: PRMT1-methylation of Twist1 is required for active E-cadherin repression. Significance: Targeting PRMT1-medi
Publikováno v:
Current heart failure reports. 14(6)
Heart failure is increasing in prevalence with a lack of recently developed therapies that produce major beneficial effects on its associated mortality. MicroRNAs are small non-coding RNA molecules that regulate gene expression, are differentially re
Autor:
Wayne Minobe, Michael R. Bristow, Robert A. Quaife, David P. Kao, Carmen C. Sucharov, Edward M. Gilbert, Brian D. Lowes, J. David Port, Karin Nunley, Anis Karimpour-Fard
Background In dilated cardiomyopathies (DCMs) changes in expression of protein-coding genes are associated with reverse remodeling, and these changes can be regulated by microRNAs (miRs). We tested the general hypothesis that dynamic changes in myoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c3f4004d0119834b227d567e9a9405
https://europepmc.org/articles/PMC5256135/
https://europepmc.org/articles/PMC5256135/