Zobrazeno 1 - 10
of 216
pro vyhledávání: '"J David Clark"'
Autor:
Yu Zhang, Andrei A Vakhtin, Jennifer S Jennings, Payam Massaband, Max Wintermark, Patricia L Craig, J Wesson Ashford, J David Clark, Ansgar J Furst
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0213952 (2020)
Evaluation of brainstem pathways with diffusion tensor imaging (DTI) and tractography may provide insights into pathophysiologies associated with dysfunction of key brainstem circuits. However, identification of these tracts has been elusive, with re
Externí odkaz:
https://doaj.org/article/41d95f134a29491fa5b9fc382626dba8
Publikováno v:
PAIN Reports, Vol 9, Iss 5, p e1179 (2024)
Abstract. Introduction:. Chronic pain is a common and problematic consequence of injuries with few proven methods for prevention or treatment. In addition to pain, functional limitations and neuropsychiatric changes such as cognitive impairment and a
Externí odkaz:
https://doaj.org/article/6b2377f8938b43ed8b01e7f14bcbf019
Autor:
Ming Zheng, Haili Zhang, David L Dill, J David Clark, Susan Tu, Arielle L Yablonovitch, Meng How Tan, Rui Zhang, Dan Rujescu, Manhong Wu, Lino Tessarollo, Wilfred Vieira, Michael M Gottesman, Suhua Deng, Livia S Eberlin, Richard N Zare, Jean-Martin Billard, Jean-Pierre Gillet, Jin Billy Li, Gary Peltz
Publikováno v:
PLoS Medicine, Vol 12, Iss 2, p e1001782 (2015)
We know very little about the genetic factors affecting susceptibility to drug-induced central nervous system (CNS) toxicities, and this has limited our ability to optimally utilize existing drugs or to develop new drugs for CNS disorders. For exampl
Externí odkaz:
https://doaj.org/article/b2f23056989947ef8256583d59db6011
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142046 (2015)
DNA methylation is a key epigenetic mechanism controlling DNA accessibility and gene expression. Blockade of DNA methylation can significantly affect pain behaviors implicated in neuropathic and inflammatory pain. However, the role of DNA methylation
Externí odkaz:
https://doaj.org/article/77266f8faced481e8b88fdc31996f730
Autor:
Rebecca Mountford, Brittany L. Adler, David Andersson, Rachael Bashford-Rogers, Richard Berwick, Stuart Bevan, Xavier Caro, Tae Hwan Chung, J. David Clark, John M. Dawes, Xinzhong Dong, Zsuzsanna Helyes, Wade Kingery, Joost J. van Middendorp, Harvey Neiland, Margot Maurer, Carmen Scheibenbogen, Katharina Schmack, Thomas Schreiner, Camilla I. Svensson, Valéria Tékus, Andreas Goebel
Publikováno v:
PAIN Reports, Vol 9, Iss 4, p e1167 (2024)
Abstract. A 2-day closed workshop was held in Liverpool, United Kingdom, to discuss the results of research concerning symptom-based disorders (SBDs) caused by autoantibodies, share technical knowledge, and consider future plans. Twenty-two speakers
Externí odkaz:
https://doaj.org/article/d2890ffbc47c48bda34575e7e82fdf06
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77881 (2013)
BACKGROUND: Dietary supplementation with methyl donors can influence the programming of epigenetic patterns resulting in persistent alterations in disease susceptibility and behavior. However, the dietary effects of methyl donors on pain have not bee
Externí odkaz:
https://doaj.org/article/629871e7bffe49eeb553f71f139508d9
Autor:
David Ruau, Joel T Dudley, Rong Chen, Nicholas G Phillips, Gary E Swan, Laura C Lazzeroni, J David Clark, Atul J Butte, Martin S Angst
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 6, p e1002538 (2012)
Identifying human genes relevant for the processing of pain requires difficult-to-conduct and expensive large-scale clinical trials. Here, we examine a novel integrative paradigm for data-driven discovery of pain gene candidates, taking advantage of
Externí odkaz:
https://doaj.org/article/14b6fb971a5a4c9481d2060ee7aeb880
Autor:
Yu Zhang, Matthew Moore, Jennifer S. Jennings, J. David Clark, Peter J. Bayley, J. Wesson Ashford, Ansgar J. Furst
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
IntroductionGulf War Illness is a type of chronic multisymptom illness, that affects about 30% of veterans deployed to the 1990–91 Persian Gulf War. Veterans deployed to Iraq/Afghanistan after 2000 are reported to have a similar prevalence of chron
Externí odkaz:
https://doaj.org/article/6f135f6f158a4a37a285196b6c31c64d
Autor:
Tian-Zhi, Guo, Xiaoyou, Shi, Wen-Wu, Li, Tzuping, Wei, Peyman, Sahbaie, J David, Clark, Wade S, Kingery
Publikováno v:
Pain. 164:421-434
Previously, we observed that B cells and autoantibodies mediated chronic nociceptive sensitization in the mouse tibia fracture model of complex regional pain syndrome and that complex regional pain syndrome patient antibodies were pronociceptive in f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d18df8af54ba3371d35b59255b8b8b4
https://doi.org/10.1097/j.pain.0000000000002725
https://doi.org/10.1097/j.pain.0000000000002725
Publikováno v:
Anesthesia & Analgesia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d51f072b78549dfaaac749617ef5ab
https://doi.org/10.1213/ane.0000000000006505
https://doi.org/10.1213/ane.0000000000006505