Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J David, Knox"'
Autor:
Kristina Jeon, Jeffrey T. Joseph, Gerard H. Jansen, Anne Peterson, J. David Knox, Valerie L. Sim
Publikováno v:
Viruses, Vol 12, Iss 12, p 1411 (2020)
Creutzfeldt–Jakob disease (CJD) is a rapidly progressive neurodegenerative disease that can arise spontaneously, genetically, or be acquired through iatrogenic exposure. Most patients die within a year of symptom onset. It is rare, affecting 1–2
Externí odkaz:
https://doaj.org/article/8a6cfaaf94b544129fc6a2e6b9f9d21a
Autor:
Benjamin K. Dawson, Andrew Gibson, J. David Knox, Keng Yeow Tay, Andrew Leung, Robert Hammond, Adrian Budhram
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce7920f835efe6671938e7fac674038
https://pubmed.ncbi.nlm.nih.gov/36274647
https://pubmed.ncbi.nlm.nih.gov/36274647
Autor:
Lili-Naz Hazrati, Gerard H. Jansen, J. David Knox, Colleen D'Arcy, Adam Rapoport, Elysa Widjaja, Jeremy N Friedman, Michael B. Coulthart, Rolande D'Amour, Snead Carter, Ari Bitnun
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 78:373-378
Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, fatal degenerative encephalopathy caused by a pathologically altered form of the prion protein (PrP). CJD is rare, with 1 and 2 cases per million per year reported in the general population, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1756ed7e78e7f9f5a773dfe27d59cea4
https://doi.org/10.1093/jnen/nlz013
https://doi.org/10.1093/jnen/nlz013
Autor:
Keding Cheng, Angela Sloan, Kristen M Avery, Michael Coulthart, Michael Carpenter, J David Knox
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84812 (2014)
Real-time quaking-induced conversion (RT-QuIC), a highly specific and sensitive assay able to detect low levels of the disease-inducing isoform of the prion protein (PrP(d)) in brain tissue biopsies and cerebral spinal fluid, has great potential to b
Externí odkaz:
https://doaj.org/article/df4bcd0473fc42b0b09d09b99deef4e5
Autor:
Lise Lamoureux, Sharon L R Simon, Margot Plews, Viola Ruddat, Simone Brunet, Catherine Graham, Stefanie Czub, J David Knox
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64044 (2013)
The difficulty in developing a diagnostic assay for Creutzfeldt - Jakob disease (CJD) and other transmissible spongiform encephalopathies (TSEs) stems in part from the fact that the infectious agent is an aberrantly folded form of an endogenous cellu
Externí odkaz:
https://doaj.org/article/cf2172f98b0b417dbf9e4fc873b06156
Autor:
Sharon L.R. Simon, Jonathan M Walker, Clark Phillipson, Anne Peterson, J. David Knox, Meika Richmond, Gerard H. Jansen
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 48(1)
Prospectively acquired Canadian cerebrospinal fluid samples were used to assess the performance characteristics of three ante-mortem tests commonly used to support diagnoses of Creutzfeldt–Jakob disease. The utility of the end-point quaking-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9352c165edfe656069aa08b1a17f702
https://pubmed.ncbi.nlm.nih.gov/32646535
https://pubmed.ncbi.nlm.nih.gov/32646535
Autor:
Joe D. O'Neil, J. David Knox, Brooks Waitt, Debra Godal, Sharon L.R. Simon, Michael Carpenter, Angela Sloan, Keding Cheng, Gary Mallinson, Dave Jackson, Jane Eastlake, Robert Vendramelli
Publikováno v:
Protein Expression and Purification. 143:20-27
Background Bacterially-produced recombinant prion protein (rPrP) has traditionally been used for in vitro fibrillation assays and reagent development for prion disease research. In recent years, it has also been used as a substrate for real-time quak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776a7e209cfdef990a7b638f87604d8f
https://doi.org/10.1016/j.pep.2017.10.007
https://doi.org/10.1016/j.pep.2017.10.007
Autor:
J. David Knox, Jeff Fuller, Stephen H. Pasternak, Ryan G. Taylor, Jorge G. Burneo, Adrian Budhram
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 46(5)
Creutzfeldt-Jakob disease (CJD) is a fatal neurological illness for which accurate diagnosis is paramount. Real-time quaking-induced conversion (RT-QuIC) is a prion-specific assay with high sensitivity and specificity for CJD. The Canadian endpoint q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c314039ccfb170eb88c3b8debd36347e
https://pubmed.ncbi.nlm.nih.gov/31266552
https://pubmed.ncbi.nlm.nih.gov/31266552
Autor:
Keding Cheng, Angela Sloan, Stuart McCorrister, Celine Nadon, Huixia Chui, Sam Ratnam, Shaun Tyler, Linda Chui, Bianli Xu, Aleisha Reimer, Sadjia Bekal, Matthew G. Walker, John L. Wylie, J. David Knox, Alyssia Robinson, Gehua Wang, Lorea A. M. Peterson, Larissa Domish, David Haldane, Drexler Hernandez, Miles R. Majcher
Publikováno v:
Journal of Clinical Microbiology
Mass spectrometry-based phenotypic H-antigen typing (MS-H) combined with whole-genome-sequencing-based genetic identification of H antigens, O antigens, and toxins (WGS-HOT) was used to type 60 clinical Escherichia coli isolates, 43 of which were pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3300ae0a18ecc5594dc4f003c93f0e
https://doi.org/10.1128/jcm.00422-16
https://doi.org/10.1128/jcm.00422-16
Autor:
Keding Cheng, Aleisha Reimer, Bianli Xu, Larissa Domish, Gehua Wang, Angela Sloan, Jun Ma, J. David Knox, Yi-Min She, Huixia Chui, Drexler Hernandez, Stuart McCorrister
Publikováno v:
Clinical Chemistry. 62:839-847
BACKGROUND Escherichia coli H antigen typing with antisera, a useful method for flagella clinical identification and classification, is a time-consuming process because of the need to induce flagella growth and the occurrence of undetermined strains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146dd2a68f8cf68561792b957c4f0d30
https://doi.org/10.1373/clinchem.2015.244236
https://doi.org/10.1373/clinchem.2015.244236