Zobrazeno 1 - 10
of 31
pro vyhledávání: '"J D Stone"'
Publikováno v:
Neuropharmacology. 44:381-389
Brain acetylcholinesterase has been targeted for the development of novel treatments for memory deficits associated with Alzheimer's disease (AD) and other neurodegenerative disorders. The long-acting AChE inhibitor donepezil (Aricept) is used to imp
Publikováno v:
The Journal of Immunology. 158:5773-5782
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Publikováno v:
The Australian journal of science. 7
Publikováno v:
British journal of experimental pathology. 27(4)
Autor:
Dale W. Sickles, Jerry J. Buccafusco, Ajay Sood, J. D. Stone, Mark A. Prendergast, Alvin V. Terry
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 305(1)
Organophosphorus (OP) compounds are detectable in the environment for years after use and endanger many populations. Although the effects of acutely toxic doses of many OP compounds are well described, much less is known about repeated low-level expo
Publikováno v:
Neurotoxicology. 21(4)
Acrylamide (ACR) and g-diketones (g-DK) produce distal sensory-motor neuropathy in a variety of species, including humans. The specific molecular site and mechanism of toxicant action leading to specific morphological and behavioral abnormalities req
Autor:
J D, Stone, L A, Conroy, K F, Byth, R A, Hederer, S, Howlett, Y, Takemoto, N, Holmes, D R, Alexander
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(12)
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Autor:
L. A. Conroy, J. D. Stone, Nick Holmes, J. A. Frearson, K. F. Byth, Sarah Howlett, Denis R. Alexander
Publikováno v:
Biochemical Society transactions. 25(2)
Publikováno v:
The American journal of physiology. 260(5 Pt 1)
Hemorrhage-induced changes in the plasma vasopressin concentration and mean arterial blood pressure (MABP) were studied in conscious rats of both sexes with and without central alpha 1-adrenoreceptor blockade. Rats were subjected to two sequential he
Autor:
S A Richman, D H Aggen, J D Stone, K S Weber, M L Dossett, D L Donermeyer, R A Mariuzza, P M Allen, P D Greenberg, D M Kranz
Publikováno v:
The Journal of Immunology. 178:S80-S80
Using T cell receptors (TCRs) for potential therapeutic applications provides an opportunity to target an expanded array of antigens, compared to those now targeted with monoclonal antibodies. Relative to antibodies, TCRs typically exhibit reduced so