Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma

Autor: D. M. Tiek, J. D. Rone, G. T. Graham, E. L. Pannkuk, B. R. Haddad, R. B. Riggins

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Abstract Glioblastoma (GBM) is an aggressive and incurable tumor of the brain with limited treatment options. Current first-line standard of care is the DNA alkylating agent temozolomide (TMZ), but this treatment strategy adds only ~4 months to media

Externí odkaz: https://doaj.org/article/d04b39e1ba5c4c6ea68bb0a9360fff81

Ovarian angiogenesis in rabbits: endotheliotrophic chemoattractant activity from isolated follicles and dispersed granulosa cells

Autor: L M Halvorson, A L Goodman, J D Rone

Publikováno v: Journal of reproduction and fertility. 97(2)

To test the hypothesis that angiogenesis is an important variable in ovarian folliculogenesis, we measured endothelial cell migration (chemotaxis) in media conditioned by rabbit ovarian cells. Endothelial cell migration, a reliable predictor of angio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f6c3ad78507d5fff624e410f4b0135
https://pubmed.ncbi.nlm.nih.gov/8501706

A synthetic peptide capable of eliciting antibodies that neutralize human chorionic gonadotropin

Autor: C C, Chang, Y Y, Tsong, J D, Rone, S J, Segal, D, Chang, J, Leban, K, Folkers

Publikováno v: Fertility and sterility. 36(5)

Antisera generated to the human chorionic gonadotropin beta-subunit (hCGbeta) have been shown not only to neutralize the biologic activity of hCG but also to cross-react with human luteinizing hormone (hLH). In an attempt to reduce such cross-reactiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7627f75698876856fb08133d9991317f
https://pubmed.ncbi.nlm.nih.gov/6171462

The changing microRNA landscape by color and cloudiness: a cautionary tale for nipple aspirate fluid biomarker analysis.

Autor: Patuleia, Susana I. S.^1,2 (AUTHOR), van der Wall, Elsken² (AUTHOR), van Gils, Carla H.³ (AUTHOR), Bakker, Marije F.³ (AUTHOR), Jager, Agnes⁴ (AUTHOR), Voorhorst-Ogink, Marleen M.¹ (AUTHOR), van Diest, Paul J.¹ (AUTHOR), Moelans, Cathy B.¹ (AUTHOR) c.b.moelans@umcutrecht.nl

Publikováno v: Cellular Oncology (2211-3428). Dec2021, Vol. 44 Issue 6, p1339-1349. 11p.

Unveiling the Influence of Tumor Microenvironment and Spatial Heterogeneity on Temozolomide Resistance in Glioblastoma Using an Advanced Human In Vitro Model of the Blood-Brain Barrier and Glioblastoma.

Autor: Lam MS; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore.; Functional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A∗STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Aw JJ; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Tan D; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Vijayakumar R; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Lim HYG; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Yada S; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Pang QY; Neuro-Oncology Research Laboratory, Department of Research, National Neuroscience Institute, Singapore, 308433, Singapore., Barker N; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Tang C; Neuro-Oncology Research Laboratory, Department of Research, National Neuroscience Institute, Singapore, 308433, Singapore.; Duke-National University of Singapore Medical School, Singapore, 169857, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore., Ang BT; Duke-National University of Singapore Medical School, Singapore, 169857, Singapore.; Department of Neurosurgery, National Neuroscience Institute, Singapore, 308433, Singapore., Sobota RM; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore.; Functional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A∗STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Pavesi A; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore.; Mechanobiology Institute, National University of Singapore, Singapore, 117411, Singapore.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2023 Dec; Vol. 19 (52), pp. e2302280. Date of Electronic Publication: 2023 Aug 30.