Zobrazeno 1 - 10 of 53 pro vyhledávání: '"J D Owen"'
1
Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia
Autor: Nadia Schoenmakers, Julia M. Keogh, Penny J. D. Owen, I. Sadaf Farooqi, Sylvie Dufour, Philippa Raymond-Barker, Elana Henning, Catherine Mitchell, Kitt Falk Petersen, Krishna Chatterjee, Samantha Northcott, Peter R. Murgatroyd, John Lazarus, David B. Savage, Douglas L. Rothman, David Halsall, Gerald I. Shulman, Suzanne Curran, Douglas E. Befroy
Publikováno v: Journal of Clinical Investigation. 120:1345-1354
Resistance to thyroid hormone (RTH), a dominantly inherited disorder usually associated with mutations in thyroid hormone receptor beta (THRB), is characterized by elevated levels of circulating thyroid hormones (including thyroxine), failure of feed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899eaca2ab0443453fd97d929850719e
https://doi.org/10.1172/jci38793
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2
Endothelial dysfunction in a murine model of thyroid hormone resistance
Autor: H. Ying, J. H. Lazarus, D. Tomlinson, Malcolm J. Lewis, Derek Lang, S. Y. Cheng, P. J. D. Owen
Publikováno v: European Journal of Clinical Investigation. 37:390-395
Background The development of a knockin mouse model of resistance to thyroid hormone (RTH) has led to a greater understanding of both the molecular and clinical behaviour of this syndrome. We have investigated the vascular response in RTH using a spe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee7e4c6e959628f442febd8aea9de7e
https://doi.org/10.1111/j.1365-2362.2007.01799.x
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3
Resistance to Thyroid Hormone in Pregnancy
Autor: Pina Amin, Simi Dhingra, John Lazarus, Penny J. D. Owen
Publikováno v: Obstetrics & Gynecology. 112:501-503
Background Resistance to thyroid hormone manifests as high serum levels of free thyroxine and free triiodothyronine, with nonsuppressed thyroid stimulating hormone (TSH) levels. We report a case series of three patients with this condition, the chang
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07992bf74136661a25a5afd507071825
https://doi.org/10.1097/aog.0b013e3181809e3a
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4
Unusual complications of thyroid carcinoma
Autor: R E Morse, P J D Owen, J H Lazarus
Thyroid carcinomas are the most frequent endocrine malignancies. Complications may arise from an established malignancy and these may lead to the initial clinical presentation or cause subsequent problems. In this case report two elderly patients wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f5f283becf61f55b0afb6c2f190e96
https://europepmc.org/articles/PMC1742594/
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5
Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins
Autor: J D, Owen, R, Strieter, M, Burdick, H, Haghnegahdar, L, Nanney, R, Shattuck-Brandt, A, Richmond
Publikováno v: International journal of cancer. 73(1)
Three human MGSA/GRO genes encode 3 highly related chemokines, MGSA/GRO alpha, -beta and -gamma. All 3 MGSA/GRO proteins bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32507574e52e800a00dbab19f9d53cd8
https://pubmed.ncbi.nlm.nih.gov/9334815
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9
Structure of the polyhedral metal–borane complex methyltriphenylphosphonium bis(dodecahydro-nido-decaborato)zincate [Ph3MeP]2[Zn(B10H12)2]
Autor: J. D. Owen, J. A. McGinnety, N. N. Greenwood
Publikováno v: J. Chem. Soc. A. :809-813
The structure of the compound [Ph3MeP]2[Zn(B10H12)2] has been determined by X-ray diffraction analysis; 4569 reflections were measured on a four-circle diffractometer. Crystals of the salt are monoclinic, space group C2/c with Z= 8 in the unit cell o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e65556586606a2d83db61e7cb56d4825
https://doi.org/10.1039/j19710000809
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10
24—THE BENDING BEHAVIOUR OF PLAIN-WEAVE FABRICS WOVEN FROM SPUN YARNS
Autor: J. D. Owen
Publikováno v: Journal of the Textile Institute. 59:313-343
The bending behaviour of square plain-weave fabrics spun and woven from nineteen different fibres, each in a range of cover factors, has been studied. It is shown how this behaviour is determined by the mechanical properties of the fibre and the fric
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86feeea4b15985fdd82f956d5353dec6
https://doi.org/10.1080/00405006808659994
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