Zobrazeno 1 - 10
of 38
pro vyhledávání: '"J D Harry"'
Publikováno v:
The Journal of Physiology. 481:689-708
1. Stretching a contracting muscle leads to greater mechanical work being done during subsequent shortening by its contractile component; the mechanism of this enhancement is not known. 2. This mechanism has been investigated here by subjecting tetan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80acd86954e87e6c63d01055873faa4f
https://doi.org/10.1113/jphysiol.1994.sp020474
https://doi.org/10.1113/jphysiol.1994.sp020474
Autor:
M Y Ruda, Gerhard Steinbeck, S R Golitsyn, J D Harry, Karl Stangl, L Van Wijk, H J J Wellens, P Touboul, M A Vos, K T Perry
Objective—To compare the efficacy and safety of a single dose of ibutilide, a new class III antiarrhythmic drug, with that of DL-sotalol in terminating chronic atrial fibrillation or flutter in haemodynamically stable patients. Design—Double blin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd8aa5efcfa5b90879a8be6b70c4f71
https://europepmc.org/articles/PMC1728725/
https://europepmc.org/articles/PMC1728725/
Autor:
S. R. Cox, Penelope Ward, H. M. Vrehen, J. D. Harry, T. Branger, J. C. C. Borleffs, A. M. M. Been-Tiktak, M. M. E. Schneider, M. Van Der Feltz
Atevirdine mesylate (U-87201E) is a new nonnucleoside (bisheteroarylpiperazine) inhibitor of human immunodeficiency virus type 1 reverse transcriptase. In a double-blind, escalating single-dose study the safety, tolerance, and pharmacokinetics of ate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f421b15a8fa26a1bee71250559651d7
https://europepmc.org/articles/PMC162591/
https://europepmc.org/articles/PMC162591/
Autor:
M. Papouchado, NP Barker, Michael A. James, AG Wardleworth, K.S. Channer, H F Marlow, J D Harry, W Bastain, J V Jones
Publikováno v:
British journal of clinical pharmacology. 29(4)
1. Six healthy male human volunteers of mean age 30.8 years (range 23-37) were given single oral doses of xamoterol (20, 50, 100 or 250 mg) and placebo with a 1 week interval between each dose. Xamoterol produced a significant decrease in systolic ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387df3c52a0fd2dce4f7c1d886964c04
https://pubmed.ncbi.nlm.nih.gov/2139340
https://pubmed.ncbi.nlm.nih.gov/2139340
Autor:
J. D. Harry
Publikováno v:
Early Phase Drug Evaluation in Man ISBN: 9781349107070
Important objectives of the early studies in man, and particularly of volunteer studies, of a putative compound include the generation of data to allow decisions to be made about the further development of the compound. This further development will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9ac5f67aa7196424698419bb9e03d3
https://doi.org/10.1007/978-1-349-10705-6_18
https://doi.org/10.1007/978-1-349-10705-6_18
Autor:
J. D. Harry
Publikováno v:
Early Phase Drug Evaluation in Man ISBN: 9781349107070
The title of this chapter is wide-ranging and to cover all aspects implicit in the title would require a book of its own. Consequently, this chapter needs to be restrictive—in particular, when it comes to interpreting the words ‘cardiovascular re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58738fd9069ac24aed0a31dc69c269ae
https://doi.org/10.1007/978-1-349-10705-6_21
https://doi.org/10.1007/978-1-349-10705-6_21
Publikováno v:
British Journal of Pharmacology. 52:275-281
1 The effects of propranolol, oxprenolol and practolol on the isometric twitch responses to electrical stimulation of isolated diaphragm muscles from the rat and of isolated papillary muscles from the rabbit are described. 2 Depression of the twitch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6861f53b80469d8aeb6683ea05e717
https://doi.org/10.1111/j.1476-5381.1974.tb09710.x
https://doi.org/10.1111/j.1476-5381.1974.tb09710.x
Publikováno v:
Postgraduate Medical Journal. 55:537-540
Summary The hypotensive effect of 25 mg, 50 mg, 75 mg, 100 mg and 0 mg of atenolol daily were compared in a double-blind within-patient study. The fall in blood pressure with 25 mg daily was not significantly different than with 100 mg. The dose resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f551066d3ea72ae1f15580df9c499c
https://doi.org/10.1136/pgmj.55.646.537
https://doi.org/10.1136/pgmj.55.646.537
Autor:
J D Harry Philip Cohen
Publikováno v:
Law, Medicine and Health Care. 9:8-37
The recent flurry of antitrust litigation in the health care industry is forcing the courts to reevaluate the legality of existing health care institutions under the Sherman Antitrust Act. One type of institution that poses significant antitrust ques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc4c045fed44b80539e43ce2ddf21d4
https://doi.org/10.1111/j.1748-720x.1981.tb00286.x
https://doi.org/10.1111/j.1748-720x.1981.tb00286.x
Publikováno v:
Heart. 40:998-1004
Fourteen patients with angina pectoris completed a double blind trial of atenolol 25 mg, 50 mg, and 100 mg twice daily and propranolol 80 mg thrice daily. In comparison with placebo, all active treatments significantly reduced anginal attacks, consum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697c6d02bec8b17333045995c7ece1bd
https://doi.org/10.1136/hrt.40.9.998
https://doi.org/10.1136/hrt.40.9.998