Zobrazeno 1 - 10
of 50
pro vyhledávání: '"J D Friesen"'
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:873-877
A series of V- and Y-shaped nucleic acids, related to the splicing intermediates derived from S. cerevisiae actin pre-mRNA, were prepared. The effects of such branched nucleic acids (bNAs) on the efficiency of in vitro pre-mRNA splicing in yeast were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db65fea89a7797111080bce8f6fe89
https://doi.org/10.1081/ncn-100002449
https://doi.org/10.1081/ncn-100002449
Publikováno v:
Molecular and Cellular Biology. 12:4142-4152
Little is known about the regions of RNA polymerase II (RNAPII) that are involved in the process of transcript elongation and interaction with elongation factors. One elongation factor, TFIIS, stimulates transcript elongation by binding to RNAPII and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c76d1df8db99399057a2399c4d3870bf
https://doi.org/10.1128/mcb.12.9.4142
https://doi.org/10.1128/mcb.12.9.4142
Autor:
J. D. Friesen, K. Schappert, T. F. Donahue, Bryan R.G. Williams, Ara G. Hovanessian, L. Feng, K. L. Chong, Eliane F. Meurs
Publikováno v:
The EMBO Journal. 11:1553-1562
The human p68 kinase is an interferon-regulated enzyme that inhibits protein synthesis when activated by double-stranded RNA. We show here that when expressed in Saccharomyces cerevisiae, the p68 kinase produced a growth suppressing phenotype resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feabe72fb1625edc5933e4d80ea1e644
https://doi.org/10.1002/j.1460-2075.1992.tb05200.x
https://doi.org/10.1002/j.1460-2075.1992.tb05200.x
Autor:
Mark G. Goebl, Fuyuhiko Tamanoi, S Petersen-Bjørn, Laurie Goodman, Yoshikazu Ohya, J D Friesen, Yasuhiro Anraku
Publikováno v:
Scopus-Elsevier
A 2.3-kilobase pair DNA fragment of the yeast CAL1 gene was cloned by complementation of the cal1-1 mutation, which causes a defect in nuclear division and bud formation (Ohya, Y., Ohsumi, Y., and Anraku, Y. (1984) Mol. & Gen. Genet. 193, 389-394). N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a55723bfc97f00498f71e86530a64c3
https://doi.org/10.1016/s0021-9258(18)98904-0
https://doi.org/10.1016/s0021-9258(18)98904-0
Publikováno v:
Molecular and Cellular Biology. 10:6123-6131
RNA polymerase II (RNAPII) is a complex multisubunit enzyme responsible for the synthesis of pre-mRNA in eucaryotes. The enzyme is made of two large subunits associated with at least eight smaller polypeptides, some of which are common to all three R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c9f1b4fba49b09b68eee6ec16fb04a
https://doi.org/10.1128/mcb.10.12.6123
https://doi.org/10.1128/mcb.10.12.6123
Publikováno v:
Journal of Bacteriology. 174:5479-5481
Certain mutations in gyrA and gyrB, the genes encoding the two subunits of DNA gyrase, are known to influence expression of the his operon (K. E. Rudd and R. Menzel, Proc. Natl. Acad. Sci. USA 84:517-521, 1987). Such mutations lead to a decrease in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427b6fd1722bd39005e8ce140840bb27
https://doi.org/10.1128/jb.174.16.5479-5481.1992
https://doi.org/10.1128/jb.174.16.5479-5481.1992
Autor:
A M, Edwards, C H, Arrowsmith, D, Christendat, A, Dharamsi, J D, Friesen, J F, Greenblatt, M, Vedadi
Publikováno v:
Nature structural biology.
Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96703d7bd62f0ec000208b58440bb1ce
https://pubmed.ncbi.nlm.nih.gov/11104003
https://pubmed.ncbi.nlm.nih.gov/11104003
Publikováno v:
Yeast (Chichester, England). 12(13)
A binding site for the transcription factor Abf1p was identified as an important promoter element of the gene that encodes Rpo26, a subunit common to all three yeast nuclear RNA polymerases (RNAP). Mutations in the Abf1p binding site were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b15062c398fb6bd2b725958166d39953
https://pubmed.ncbi.nlm.nih.gov/8923739
https://pubmed.ncbi.nlm.nih.gov/8923739
Autor:
J D Friesen, D J Field
Publikováno v:
Genesdevelopment. 10(4)
Base-pairing between U2 and U6 snRNAs to form intermolecular helix II has been demonstrated previously as a requirement for pre-mRNA splicing in mammalian cells. In contrast, deletion and substitution mutation experiments in yeast have indicated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80bbe98de02a42745a1b320b6801e1b
https://pubmed.ncbi.nlm.nih.gov/8600031
https://pubmed.ncbi.nlm.nih.gov/8600031
Publikováno v:
Nucleic acids symposium series. (33)
Several distinct domains of U4 small nuclear (sn)RNA interact with other components of the spliceosome and are essential for pre-mRNA splicing. We have previously shown that single point mutations (Hu et al., 1995) in the central domain of the yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e854e1a7946ea2fd7918883302e7a29
https://pubmed.ncbi.nlm.nih.gov/8643386
https://pubmed.ncbi.nlm.nih.gov/8643386