Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J D, Yager"'
Publikováno v:
Cancer research. 61(20)
Many of the major identified risk factors for breast cancer are associated with exposure to endogenous estrogen. In addition to the effects of estrogen as a growth factor, experimental and epidemiological evidence suggest that catechol metabolites of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::765ef9fff3bd5bb10166f728b5da5f4f
https://pubmed.ncbi.nlm.nih.gov/11606384
https://pubmed.ncbi.nlm.nih.gov/11606384
Autor:
J D, Yager
Publikováno v:
Journal of the National Cancer Institute. Monographs. (27)
A common thread linking the main risks for developing breast cancer in women is cumulative, excessive exposure to estrogen. The standard paradigm to account for this association focuses on increased cell proliferation caused by estrogen through estro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4f9d7b53c60919276296c4e933472f1
https://pubmed.ncbi.nlm.nih.gov/10963620
https://pubmed.ncbi.nlm.nih.gov/10963620
Autor:
C R, Jefcoate, J G, Liehr, R J, Santen, T R, Sutter, J D, Yager, W, Yue, S J, Santner, R, Tekmal, L, Demers, R, Pauley, F, Naftolin, G, Mor, L, Berstein
Publikováno v:
Journal of the National Cancer Institute. Monographs. (27)
Estrogen exposure represents the major known risk factor for development of breast cancer in women and is implicated in the development of prostate cancer in men. Human breast tissue has been shown to be a site of oxidative metabolism of estrogen due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b9e1d6b7e85092ddb6d7a5c0f8e2d36
https://pubmed.ncbi.nlm.nih.gov/10963622
https://pubmed.ncbi.nlm.nih.gov/10963622
Publikováno v:
Carcinogenesis. 21(6)
Ethinyl estradiol (EE) is a strong promoter of hepatocarcinogenesis in the rat. Treatment with EE and other hepatic promoters induces transient growth stimulation followed by growth inhibition (mitosuppression) in hepatocytes. Previously, we identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c43bb81b38128d0b3754c8ef1d024c2
https://pubmed.ncbi.nlm.nih.gov/10837011
https://pubmed.ncbi.nlm.nih.gov/10837011
Autor:
K J, Helzlsouer, A J, Alberg, H Y, Huang, S C, Hoffman, P T, Strickland, J W, Brock, V W, Burse, L L, Needham, D A, Bell, J A, Lavigne, J D, Yager, G W, Comstock
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 8(6)
A nested case-control study was conducted to examine the association between serum concentrations of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE), the primary metabolite of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), and polychlorinate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69f0457058b47ae15379589374eccc0e
https://pubmed.ncbi.nlm.nih.gov/10385143
https://pubmed.ncbi.nlm.nih.gov/10385143
Autor:
J A, Lavigne, K J, Helzlsouer, H Y, Huang, P T, Strickland, D A, Bell, O, Selmin, M A, Watson, S, Hoffman, G W, Comstock, J D, Yager
Publikováno v:
Cancer research. 57(24)
Mounting evidence suggests that catechol metabolites of estradiol may contribute to the development of estrogen-induced cancers. O-Methylation, catalyzed by catechol-O-methyltransferase (COMT), inactivates catechol estrogens. COMT is polymorphic in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7262fac9e5b915be1881ecc5d0db0ef1
https://pubmed.ncbi.nlm.nih.gov/9407957
https://pubmed.ncbi.nlm.nih.gov/9407957
Publikováno v:
Carcinogenesis. 17(12)
In this study, our goal was to identify genes whose expression in liver is altered in female F-344 rats during mitosuppression induced by 42 days of ethinyl estradiol (EE) treatment (Yager et al., Carcinogenesis, 15, 2117-2123, 1994). Northern analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e09ddc47325814fee7296d090ba5a581
https://pubmed.ncbi.nlm.nih.gov/9006120
https://pubmed.ncbi.nlm.nih.gov/9006120
Publikováno v:
Hepatology (Baltimore, Md.). 22(1)
A problem traditionally encountered with primary hepatocyte cultures is their rapid dedifferentiation, which is reflected not only in decreased liver-specific functions, but also in dedifferentiated morphology: the cells flatten, depolarize, and lose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e40115e231b395f0b19c806be6b4a6af
https://pubmed.ncbi.nlm.nih.gov/7601410
https://pubmed.ncbi.nlm.nih.gov/7601410
Autor:
N, Ni, J D, Yager
Publikováno v:
Hepatology (Baltimore, Md.). 19(1)
Ethinyl estradiol is a weak complete carcinogen and potent tumor promoter. In vivo, ethinyl estradiol causes a rapid but transient increase in liver growth, whereas in cultured female hepatocytes it enhances DNA synthesis induced by epidermal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26f0c4a2c07a2c68e596effceb546564
https://pubmed.ncbi.nlm.nih.gov/7506224
https://pubmed.ncbi.nlm.nih.gov/7506224
Autor:
J D, Yager, Y E, Shi
Publikováno v:
Progress in clinical and biological research. 369
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f66a1d03f66af1ae96912c1acac77f1
https://pubmed.ncbi.nlm.nih.gov/1835096
https://pubmed.ncbi.nlm.nih.gov/1835096