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pro vyhledávání: '"J D, Tyndall"'
Autor:
J D, Tyndall, D P, Fairlie
Publikováno v:
Journal of molecular recognition : JMR. 12(6)
Crystal structures for several hundred protease-inhibitor complexes have been analysed and their superimpositions have been used to demonstrate a universal relationship between inhibitor/substrate conformation and molecular recognition by all asparti
Autor:
X, Huang, M P, Cuajungco, C S, Atwood, M A, Hartshorn, J D, Tyndall, G R, Hanson, K C, Stokes, M, Leopold, G, Multhaup, L E, Goldstein, R C, Scarpa, A J, Saunders, J, Lim, R D, Moir, C, Glabe, E F, Bowden, C L, Masters, D P, Fairlie, R E, Tanzi, A I, Bush
Publikováno v:
The Journal of biological chemistry. 274(52)
Oxidative stress markers as well as high concentrations of copper are found in the vicinity of Abeta amyloid deposits in Alzheimer's disease. The neurotoxicity of Abeta in cell culture has been linked to H(2)O(2) generation by an unknown mechanism. W