Zobrazeno 1 - 10 of 31 pro vyhledávání: '"J D, Stuart"'
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Akademický článek
Report of the Departmental Committee on Bond Investment Companies
Autor: BUTCHER, J. G., COCKBURN, HENRY, SIM, J. D. STUART, BARNES, G. S., PAYNE, H. A.
Publikováno v: Journal of the Institute of Actuaries (1886-1994), 1906 Jan 01. 40(1), 99-116.
Externí odkaz: https://www.jstor.org/stable/41136435
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2
Inhibition of Human Steroid 5α Reductases type I and II by 6-Aza-Steroids: Structural Determinants of One-Step vs Two-Step Mechanism
Autor: Marcia L. Moss, I R Patel, A. G. Peranteau, G. Tian, Stephen V. Frye, Sue H. Kadwell, J. D. Stuart, L. K. Overton, Petr Kuzmic, T. A. Kost
Publikováno v: Scopus-Elsevier
We have discovered that 17β-[N,N-(diethyl)carbamoyl]-6-azaandrost-4-en-3-one is a time-dependent inhibitor of type II 5α-reductase, as is the drug finasteride. Unlike finasteride, the 6-aza-steroid is not a time-dependent inhibitor of type I 5α-re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c892d263df65a95906b65268cca172d
https://doi.org/10.1021/bi952472+
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3
17.beta.-(N-tert-Butylcarbamoyl)-4-aza-5.alpha.-androstan-1-en-3-one Is an Active Site-Directed Slow Time-Dependent Inhibitor of Human Steroid 5.alpha.-Reductase 1
Autor: Sue H. Kadwell, Domanico Pl, J. D. Stuart, G. Tian, Marcia L. Moss, T. A. Kost, L. K. Overton, Robert A. Mook, I R Patel, H. N. Bramson
Publikováno v: Biochemistry. 33:2291-2296
17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one (finasteride), which has been approved for treatment of benign prostatic hyperplasia, is shown here to be a slow time-dependent inhibitor of human steroid 5 alpha-reductase isozyme 1.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734895a64604489e39df0587cc4ba7af
https://doi.org/10.1021/bi00174a041
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6
Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5alpha-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat
Autor: J D, Stuart, F W, Lee, D, Simpson Noel, S H, Kadwell, L K, Overton, C R, Hoffman, T A, Kost, T K, Tippin, R L, Yeager, K W, Batchelor, H N, Bramson
Publikováno v: Biochemical pharmacology. 62(7)
The interaction of baculovirus expressed rat steroid 5alpha-reductase types 1 and 2 (r5AR1 and r5AR2) with 17beta-N-(2,5-bis(trifluoromethyl)phenyl)carbamoyl-4-aza-5alpha-androst-1-en-3-one (GI198745) was investigated at pH 7 and 37 degrees. This 5al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74b67dc463dbf35e4e8f4311611baf45
https://pubmed.ncbi.nlm.nih.gov/11543729
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7
Inhibition of human steroid 5alpha reductases type I and II by 6-aza-steroids: structural determinants of one-step vs two-step mechanism
Autor: M L, Moss, P, Kuzmic, J D, Stuart, G, Tian, A G, Peranteau, S V, Frye, S H, Kadwell, T A, Kost, L K, Overton, I R, Patel
Publikováno v: Biochemistry. 35(11)
We have discovered that 17beta-[N,N-(diethyl)carbamoyl]-6-azaandrost-4-en-3-one is a time-dependent inhibitor of type II 5alpha-reductase, as is the drug finasteride. Unlike finasteride, the 6-aza-steroid is not a time-dependent inhibitor of type I 5
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73b1f638df7a6de1206a267264c13d20
https://pubmed.ncbi.nlm.nih.gov/8639496
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9
Single-donor fibrin glue for hand burns
Autor: John G. Kenney, J. D. Stuart, Raymond F. Morgan
Publikováno v: Annals of plastic surgery. 24(6)
Early tangential excision sometimes results in considerable blood loss, prolonged operative time, and partial loss of the graft secondary to hematoma formation. Previous reports document positive hemostatic effects and improved skin fixation with fib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63423190828a102771de01cd11b41704
https://pubmed.ncbi.nlm.nih.gov/2363566
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