Zobrazeno 1 - 10
of 45
pro vyhledávání: '"J D, Milton"'
Autor:
P. J. D. Milton, D. A. Sanderson
Publikováno v:
Journal of Obstetrics and Gynaecology. 11:320-323
SummaryIn a retrospective study of 4300 ultrasound scans for placental localisation 505 patients were described as having ‘low-lying’ placentas on a scan performed at 18–20 weeks pregnant. When these were divided into two groups with the placen
Publikováno v:
Glycoconjugate journal. 18(7)
The dietary lectins, edible mushroom (ABL) and Jacalin (JAC) inhibit the proliferation of colonic cancer cells, whereas Amaranth (ACL) and peanut (PNA) stimulate their proliferation. All these lectins share as their preferred ligand the Thomsen-Fried
Publikováno v:
Journal of cellular physiology. 186(2)
Increased cell surface expression of the Thomsen-Friedenreich antigen (TF antigen, Galbeta1-3GalNAcalpha-) is a common feature in malignant and pre-malignant epithelia. Our previous studies have shown that dietary TF-binding lectins from peanut (Arac
Publikováno v:
Digestion. 59(6)
CAM 17.1 is an antimucin monoclonal antibody which has recently been proven valuable as a reagent for serological diagnosis of pancreatic cancer. A series of studies have been performed to characterise its epitope. First it was screened immunohistoch
Autor:
L G, Yu, B, Jansson, D G, Fernig, J D, Milton, J A, Smith, O V, Gerasimenko, M, Jones, J M, Rhodes
Publikováno v:
International journal of cancer. 73(3)
In many tissues, the TF (Thomsen-Friedenreich) blood group antigen (Galbeta1-3GalNAc alpha-) behaves as an onco-foetal carbohydrate antigen, showing increased expression in malignancy and hyperplasia. Dietary lectins which bind the TF antigen have ma
Publikováno v:
Gut. 40(2)
BACKGROUND/AIMS: Regional differences in the biology of the colonic epithelium may determine the extent of involvement by ulcerative colitis. Novel monoclonal antibodies (MAbs) were used in this study to investigate regional heterogeneity in the colo
Publikováno v:
Pediatrics. 96(3 Pt 1)
To describe the pattern of immunization in the cohort of children who entered public schools in Virginia in 1992.This was a historic cohort study using stratified cluster sampling. Three strata were created based on the socioeconomic status (SES) of
Publikováno v:
Gut. 36(4)
Colonic mucin is heavily sulphated and it has been shown that enzymatic desulphation by faecal bacterial sulphatases greatly increases its susceptibility to degradation by faecal glycosidases. A possible role for faecal mucin sulphatase in the pathog
Autor:
P. R. Raggatt, M. E. Ferguson-Smith, C. Carr, Malcolm A. Ferguson-Smith, P. J. D. Milton, S. F. Goodburn, A. J. Kershaw, J. R. W. Yates
Publikováno v:
Prenatal diagnosis. 14(5)
Over a 2-year period from January 1991 to December 1992, second-trimester maternal serum screening for Down's syndrome using alpha-fetoprotein (alpha FP), human chorionic gonadotrophin (hCG), and unconjugated oestriol (uE3) was made available to five
Publikováno v:
Cancer research. 53(19)
Galactosyl beta-1,3-N-acetyl galactosamine (Gal beta-1,3-GalNAc) (Thomsen Friedenreich antigen), the Class I core sequence in O-linked oligosaccharide chains, behaves as an oncofetal antigen showing increased expression in many epithelial malignancie