Zobrazeno 1 - 10
of 62
pro vyhledávání: '"J D, Lutton"'
Publikováno v:
Experimental Biology and Medicine. 229:12-20
Multiple sclerosis (MS) is a complex human autoimmune-type disease with a predominantly unknown etiology. Immunologic destruction of myelin basic protein (MBP) throughout the nervous system is the major pathology of multiple sclerosis. This review wi
Publikováno v:
Acta Haematologica. 98:76-82
We determined the in vivo ability of infused human recombinant hemoglobin 1.1 (hr-Hb) and erythropoietin to rescue the hematopoietic activity from the suppressive effects of AZT in normal and in a murine model of AIDS (MAIDS) mice. Mice were fed with
Publikováno v:
Leukemia Research. 18:531-539
A leukemoid reaction occurs after inoculation of L1210 leukemic cells into recipient mice and the degree of granulocytosis is correlated with tumor progression. It was found that the sera of leukemic mice contained elevated levels of colony stimulati
Autor:
Gili Kenet, M.F. Doyle, G. Kende, U. Seay, A. Al-Rashied, Frida Brok-Simoni, Carlos Cerrezuela, Adekunle Adekile, L. Pérènyi, B. Opalka, K. Quabeck, D. Thurston, J. Lohmeyer, L. Diekmann, Bracha Ramot, D. Glenn, Titus H.J. Huisman, H. Schulte Holthausen, L. Al-Fuzae, Dietrich W. Beelen, Amos Toren, I. Ben-Bassat, M. Mandel, L.-H. Gu, Mohammad Z. Haider, Petr Lemež, E. Baysal, Ernest Beutler, Nashat Gabrail, U.W. Schaefer, S. Moqattash, R. Bützler, Y. Neumann, P. Garver, Reinhard Becher, N. G. Abraham, H. Pralle, K.C. Aboobacker, A. Käbisch, G. Rechavi, Stanley Anderson, Marwan F. Abu-Hijleh, Peter Kern, Boris Modrau, Manfred Dietrich, Dorothee von Laer, J. D. Lutton
Publikováno v:
Acta Haematologica. 92:I-IV
Publikováno v:
Acta Haematologica. 92:182-186
We studied the toxic effects of azidothymidine (AZT) on the hemopoietic colony growth (CFU-E, BFU-E and CFU-GM) of bone marrow in a murine model of AIDS (MAIDS). A sparing effect by recombinant hemoglobin (r-Hb) on AZT suppression of MAIDS bone marro
Autor:
J. L. Chertkov, Attallah Kappas, Richard D. Levere, Shanlong Jiang, Nader G. Abraham, Jonathan S. Harrison, J. D. Lutton
Publikováno v:
Blood. 82:3574-3579
The ability of combination treatment with erythropoietin (Epo) and heme to rescue hematopoietic activity in mice from the suppressive effect of azidothymidine (AZT) was determined. Exposure of mice to AZT for 5 weeks produced marked anemia, thrombocy
Autor:
Shigeki Shibahara, Richard D. Levere, Attallah Kappas, Margaret O. Griffin, Nader G. Abraham, J. D. Lutton, Miki Nishimura
Publikováno v:
Hepatology. 17:861-868
Exposure of Hep3B cells to metalloporphyrins (tinprotoporphyrin and heme) or cobalt chloride resulted in the production of a significant number of heme oxygenase transcripts, erythropoietin transcripts or both, as indicated by in situ hybridization.
Autor:
Dietmar Fuchs, Richard D. Levere, Günter Weiss, Attallah Kappas, Helmut Wachter, Nader G. Abraham, J. D. Lutton, Gunter Bock, Gabriele Werner-Felmayer
Publikováno v:
Experimental Biology and Medicine. 202:470-475
Previous results have demonstrated links between cell-mediated immunity, interferon (IFN)-gamma and neopterin production with heme, porphyrins, and iron metabolism. In this study, we compared the effects of heme, several metalloporphyrins, protoporph
Autor:
Jonathan S. Harrison, J. L. Chertkov, Nader G. Abraham, M. Tiefenthaler, J. D. Lutton, Richard D. Levere, Shanlong Jiang
Publikováno v:
STEM CELLS. 11:218-227
In this study we report on the establishment of novel conditions which permit efficient ret-rovirus-mediated gene transfer of human adenosine deaminase (ADA) into murine hematopoietic progenitors. Using Southern blot analysis and an ADA probe, we dem
Autor:
A. C. Brown, J. D. Lutton, Richard D. Levere, Satei T. Moqattash, N. G. Abraham, J.‐L. da Silva
Publikováno v:
Journal of Cellular Biochemistry. 49:259-265
In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental agents. Exposure of Hep3B cells to hemin (10 microM) for as little as 5 min resulted in signific