Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J D, Lutterbaugh"'
Publikováno v:
Cancer research. 61(3)
Serological tumor markers have proven valuable in the care of individuals with cancer for the early detection of primary cancers, early detection of cancer relapse, monitoring the response of cancers to therapy, and as predictors of cancer prognosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48cf0ddd2980433192bdb8114fccb057
https://pubmed.ncbi.nlm.nih.gov/11221878
https://pubmed.ncbi.nlm.nih.gov/11221878
Autor:
S P, Fink, S E, Swinler, J D, Lutterbaugh, J, Massagué, S, Thiagalingam, K W, Kinzler, B, Vogelstein, J K, Willson, S, Markowitz
Publikováno v:
Cancer research. 61(1)
Transforming growth factor-beta (TGF-beta) inhibits growth and induces apoptosis of colon epithelial cells. Binding of TGF-beta to its receptor induces phosphorylation of the Smad proteins Smad2 and Smad3, which then form heteromeric complexes with S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa5f865552097265ea6564ed6eda875d
https://pubmed.ncbi.nlm.nih.gov/11196171
https://pubmed.ncbi.nlm.nih.gov/11196171
Autor:
W M, Grady, L L, Myeroff, S E, Swinler, A, Rajput, S, Thiagalingam, J D, Lutterbaugh, A, Neumann, M G, Brattain, J, Chang, S J, Kim, K W, Kinzler, B, Vogelstein, J K, Willson, S, Markowitz
Publikováno v:
Cancer research. 59(2)
We previously demonstrated that mutational inactivation of transforming growth factor beta type II receptors (RIIs) is very common among the 13% of human colon cancers with microsatellite instability. These mutations principally cluster in the BAT-RI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b60b02d6993322022344690d7132702
https://pubmed.ncbi.nlm.nih.gov/9927040
https://pubmed.ncbi.nlm.nih.gov/9927040
Autor:
J R, Eshleman, S D, Markowitz, P S, Donover, E Z, Lang, J D, Lutterbaugh, G M, Li, M, Longley, P, Modrich, M L, Veigl, W D, Sedwick
Publikováno v:
Oncogene. 12(7)
Colon cancer and an increasing number of other cancers have been found to exhibit instability of DNA microsatellite sequences. Such tumors have been designated as replication errors (RER) tumors. However, as microsatellites are only rarely found with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff0e5d17715aef3eab50852f825404cc
https://pubmed.ncbi.nlm.nih.gov/8622858
https://pubmed.ncbi.nlm.nih.gov/8622858