Zobrazeno 1 - 10
of 632
pro vyhledávání: '"J D, Laskin"'
Autor:
Jasim, Saade Abdalkareem1 (AUTHOR), Al‐Dhalimy, Aiman Mohammed Baqir2 (AUTHOR), Zokaei, Maryam3,4 (AUTHOR), Salimi, Shadi5 (AUTHOR), Alnajar, Mohammed Jawad6 (AUTHOR), Kumar, Abhinav7,8,9 (AUTHOR), Alwaily, Enas R.10 (AUTHOR), Zwamel, Ahmed Hussein11 (AUTHOR), Hussein, Soura Alaa12 (AUTHOR), Gholami‐Ahangaran, Majid13 (AUTHOR) mgholami6@gmail.com
Publikováno v:
Veterinary Medicine & Science. Nov2024, Vol. 10 Issue 6, p1-12. 12p.
Publikováno v:
ChemInform. 23
Publikováno v:
Advances in experimental medicine and biology. 500
One of the hallmarks of the inflammatory response associated with tissue injury is the accumulation of macrophages at sites of damage. These cell types release proinflammatory cytokines and cytotoxic mediators to destroy invading pathogens and initia
Publikováno v:
Advances in experimental medicine and biology. 500
Much ongoing research in toxicology focuses on a hypothesis-driven mechanism of action approach aimed at understanding the molecular events mediating the actions of the chemicals of interest. Using this approach, investigators develop hypotheses base
Publikováno v:
Journal of leukocyte biology. 70(2)
Although initially considered merely "scavenger cells" that participate in immunologic responses only after B and T lymphocytes have performed their biological tasks, more recent evidence suggests that macrophages play a key role in host defense as w
Autor:
B, Billack, D E, Heck, D M, Porterfield, R P, Malchow, P J, Smith, C R, Gardner, D L, Laskin, J D, Laskin
Publikováno v:
Biochemical pharmacology. 61(12)
Pharmacological modulation of nitric oxide synthase activity has been achieved using structural analogs of arginine. In the present studies, we demonstrated that the minimal amidine structure required for enzymatic inhibition is formamidine. We found
Publikováno v:
Pharmacologytherapeutics. 84(3)
Nitric oxide is produced by many cell types in the lung and plays an important physiologic role in the regulation of pulmonary vasomotor tone by several known mechanisms. Nitric oxide stimulates soluble guanylyl cyclase, resulting in increased levels
Autor:
Johnston, Richard A.1,2,3,4 (AUTHOR) rfj1@cdc.gov, Pilkington, Albert W.1 (AUTHOR), Atkins, Constance L.5 (AUTHOR), Boots, Theresa E.1 (AUTHOR), Brown, Philip L.1 (AUTHOR), Jackson, William T.3 (AUTHOR), Spencer, Chantal Y.6 (AUTHOR), Siddiqui, Saad R.3 (AUTHOR), Haque, Ikram U.3,7 (AUTHOR)
Publikováno v:
Physiological Reports. Apr2024, Vol. 12 Issue 8, p1-17. 17p.
Publikováno v:
Biochemical pharmacology. 54(1)
Nitric oxide is an important cellular mediator produced in keratinocytes and macrophages from arginine by the enzyme nitric oxide synthase during inflammatory reactions in the skin. We found that gamma-interferon stimulated nitric oxide production an
Publikováno v:
Cancer research. 56(9)
Nitric oxide is an important cellular mediator that plays a role in regulating cellular proliferation of both normal and tumor cells. In the present study, we characterized nitric oxide production by the human colon adenocarcinoma cell line DLD-1 and