Výsledky vyhledávání - "J D, Helmann"

Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA

Autor: A F, Herbig, J D, Helmann

Publikováno v: Molecular microbiology. 41(4)

The inducible response to H(2)O(2) stress in Bacillus subtilis is under the control of PerR, one of three Fur homologues in this organism. PerR was purified in both an inactive, metal-dependent form and an active, metal-containing form as determined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2df5aa5a10626d28e8dd680f62f49826
https://pubmed.ncbi.nlm.nih.gov/11532148

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Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins

Autor: Q, Que, J D, Helmann

Publikováno v: Molecular microbiology. 35(6)

The Bacillus subtilis yqhN gene encodes a metalloregulatory protein distantly related to the Corynebacterium diphtheriae diphtheria toxin repressor (DtxR). While DtxR mediates the iron-dependent repression of iron uptake, we demonstrate that yqhN (he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7fb04bb92852ef7da14ef85e4377b2e4
https://pubmed.ncbi.nlm.nih.gov/10760146

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Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search

Autor: X, Huang, J D, Helmann

Publikováno v: Journal of molecular biology. 279(1)

The promoter selectivity of RNA polymerase (RNAP) can be altered by the association with alternative sigma subunits. Bacillus subtilis hosts a multitude of sigma factors, several of which coordinate the complex developmental program culminating in en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b63980fd4d23db961a6b802b7ea668d3
https://pubmed.ncbi.nlm.nih.gov/9636707

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Structural analysis of the Bacillus subtilis delta factor: a protein polyanion which displaces RNA from RNA polymerase

Autor: F J, López de Saro, A Y, Woody, J D, Helmann

Publikováno v: Journal of molecular biology. 252(2)

RNA polymerase from Bacillus subtilis is a complex mixture comprising a common core (beta beta' alpha 2), the 20.4 kDa delta (delta) protein, and of one of several sigma (sigma) specificity factors. The delta protein, together with several truncated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::717583da833a24234a75a1aa61f47315
https://pubmed.ncbi.nlm.nih.gov/7545758

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The delta subunit of Bacillus subtilis RNA polymerase. An allosteric effector of the initiation and core-recycling phases of transcription

Autor: Y L, Juang, J D, Helmann

Publikováno v: Journal of molecular biology. 239(1)

RNA polymerase purified from Bacillus subtilis contains multiple sigma (sigma) factors and an auxiliary subunit known as delta (delta). We have addressed the roles of the delta polypeptide in a model transcription cycle using the promoter and attenua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03d74dd067d78372268207a9763d5c2a
https://pubmed.ncbi.nlm.nih.gov/7515111

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A mismatch bubble in double-stranded DNA suffices to direct precise transcription initiation by Escherichia coli RNA polymerase

Autor: S E, Aiyar, J D, Helmann, P L, deHaseth

Publikováno v: The Journal of biological chemistry. 269(18)

Formation of a transcription-competent "open" complex between Escherichia coli RNA polymerase and a promoter, where base pairing is disrupted over a region of 12 base pairs including the start site of transcription, is a complex process involving at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88049255c772cc7a7973306f3e5fa061
https://pubmed.ncbi.nlm.nih.gov/8175746

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A promoter melting region in the primary sigma factor of Bacillus subtilis. Identification of functionally important aromatic amino acids

Autor: Y L, Juang, J D, Helmann

Publikováno v: Journal of molecular biology. 235(5)

Sigma factor (sigma) is a dissociable subunit of bacterial RNA polymerase that determines promoter recognition. It has been proposed that a cluster of highly conserved aromatic amino acids in bacterial sigma factors (region 2.3) defines a melting mot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f092e78ccefead6cb53573b01b65f7c
https://pubmed.ncbi.nlm.nih.gov/8107087

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The Agrobacterium Tumefaciens Transcriptional Activator OccR Causes a Bend at a Target Promoter that is Partially Relaxed by a Plant Tumor Metabolite

Autor: S. C. Winans, J. D. Helmann, K. Cho, Lu Wang

Publikováno v: Advances in Molecular Genetics of Plant-Microbe Interactions, Vol. 2 ISBN: 9789048142217

Crown gall tumors incited by A. tumefaciens release compounds called opines, which serve as nutrient sources and as signal molecules for the colonizing bacteria. One such opine, octopine, induces expression of a cognate catabolism operon (occQ) via a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::826abfa8a14bf8dd6e17f23849d629d0
https://doi.org/10.1007/978-94-017-0651-3_13

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