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pro vyhledávání: '"J D, Ernst"'
Autor:
J L Rosales, J D Ernst
Publikováno v:
The Journal of Immunology. 159:6195-6202
To gain direct access to the secretory machinery and study the regulation, mechanisms, and effectors of Ca2+-dependent neutrophil secretion, we developed an efficient and reproducible method of plasma membrane permeabilization using streptolysin O. W
Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species
Publikováno v:
Journal of Clinical Investigation. 98:2050-2059
Mesothelial cells, the progenitor cell of the asbestos-induced tumor mesothelioma, are particularly sensitive to the toxic effects of asbestos, although the molecular mechanisms by which asbestos induces injury in mesothelial cells are not known. We
Autor:
J D Ernst
Publikováno v:
The Journal of Immunology. 146:3110-3114
After phagocytosis, killing and digestion of ingested microorganisms depend on fusion of phagocytic vesicle membranes with membranes of intracellular vesicles (azurophil and specific granules). There is considerable evidence that phagosome-granule me
Autor:
J D, Ernst
Publikováno v:
Cellular microbiology. 2(5)
The concerted study of molecular mechanisms of phagocytosis and the inhibition of phagocytosis by specific products of extracellular bacterial pathogens has borne considerable fruit. The importance of tyrosine phosphorylation and of the Rho family of
Autor:
J L, Rosales, J D, Ernst
Publikováno v:
Journal of cellular biochemistry. 80(1)
Guanosine triphosphate (GTP) has been implicated in the regulation of Ca(2+)-mediated secretion from neutrophils. We further examined the role of GTP in neutrophil secretion using streptolysin O permeabilized cells. We found that, in the presence of
Autor:
J D, Ernst
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 29(5)
On 26 and 27 October 1998, the Department of Medicine at the University of California, San Francisco (UCSF), hosted a symposium and workshop on bacterial vaccines. The symposium featured invited speakers who are internationally recognized authorities
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(7)
IFN-gamma activates macrophages to kill diverse intracellular pathogens, but does not activate human macrophages to kill virulent Mycobacterium tuberculosis. We tested the hypothesis that this is due to inhibition of IFN-gamma signaling by M. tubercu
Autor:
J L, Rosales, J D, Ernst
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(12)
To gain direct access to the secretory machinery and study the regulation, mechanisms, and effectors of Ca2+-dependent neutrophil secretion, we developed an efficient and reproducible method of plasma membrane permeabilization using streptolysin O. W
Publikováno v:
Environmental health perspectives, vol 105 Suppl 5, iss Suppl 5
Environmental health perspectives, vol 105 Suppl 5, iss suppl 5
Environmental Health Perspectives
Environmental health perspectives, vol 105 Suppl 5, iss suppl 5
Environmental Health Perspectives
Mesothelial cells, the progenitor cells of the asbestos-induced tumor mesothelioma, are particularly sensitive to the toxic effects of asbestos, although the molecular mechanisms by which asbestos induces injury in mesothelial cells are not known. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddee98b9a29697726e4088f5b556e107
https://escholarship.org/uc/item/5561s8dd
https://escholarship.org/uc/item/5561s8dd
Autor:
J D Ernst
To understand further the structural basis of phospholipid binding by annexin I, three monoclonal antibodies that compete with Ca2+ and phospholipids for binding of annexin I were used to screen an expression library containing fragments of bovine an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3e761c965e6a7b5b8ee5650ff70e0e
https://europepmc.org/articles/PMC1132201/
https://europepmc.org/articles/PMC1132201/