Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J D, Elsworth"'
Autor:
J. R. Sladek Ph.D., K. B. Bjugstad, T. J. Collier, E. A. Bundock, B. C. Blanchard, J. D. Elsworth, R. H. Roth, D. E. Redmond
Publikováno v:
Cell Transplantation, Vol 17 (2008)
Transplantation of embryonic dopamine (DA) neurons has been tested as a therapy for Parkinson's disease. Most studies placed DA neurons into the striatum instead of the substantia nigra (SN). Reconstruction of this DA pathway could serve to establish
Externí odkaz:
https://doaj.org/article/1c8db4ed76da4c3abe500c776d559660
Autor:
Kimberly B. Bjugstad, D. Eugene Redmond, Yang D. Teng, J. D. Elsworth, R. H. Roth, B. C. Blanchard, Evan Y. Snyder, John R. Sladek
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Neural stem cells (NSC) have been shown to migrate towards damaged areas, produce trophic factors, and replace lost cells in ways that might be therapeutic for Parkinson's disease (PD). However, there is very little information on the effects of NSC
Externí odkaz:
https://doaj.org/article/81d6a7d0a8d845dca89becdf8e22a477
Publikováno v:
Synapse (New York, N.Y.). 36(2)
Previously, we reported that R(+)HA-966, a weak partial agonist for the glycine/NMDA receptor, and guanfacine, a noradrenergic alpha2 agonist, have anxiolytic-like actions on the biochemical activation of the mesoprefrontal dopamine neurons and fear-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92d62013f3dcfb0cb6b21e83b7a3baed
https://pubmed.ncbi.nlm.nih.gov/10767061
https://pubmed.ncbi.nlm.nih.gov/10767061
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
This report investigates the effect of the negative enantiomer of 1-hydroxy-3-aminopyrrolidone-2 (HA-966) on behavioral and biochemical changes elicited by pharmacological or experimental paradigms which activate mesocorticolimbic dopaminergic neurot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35b6f7a846dac64fca055958dff28ba0
https://pubmed.ncbi.nlm.nih.gov/9353390
https://pubmed.ncbi.nlm.nih.gov/9353390
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::165c4ee39d084ca58f317a407b369db0
https://pubmed.ncbi.nlm.nih.gov/9328021
https://pubmed.ncbi.nlm.nih.gov/9328021
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
D2 dopamine receptor antagonism is postulated to be the key to antipsychotic efficacy in the treatment of schizophrenia. Yet the D1 dopamine family of receptors is far more prevalent in the cortical areas of the brain, such as the prefrontal cortex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81c819c56136658a6b3d02ad635018ce
https://pubmed.ncbi.nlm.nih.gov/9103549
https://pubmed.ncbi.nlm.nih.gov/9103549
Autor:
A Y, Deutch, D A, Lewis, R E, Whitehead, J D, Elsworth, M J, Iadarola, D E, Redmond, R H, Roth
Publikováno v:
Synapse (New York, N.Y.). 23(3)
Recent studies have reported that acute administration of dopamine D2 receptor antagonists increases expression of the immediate early gene c-fos in the rat striatal complex. There have been no corresponding studies of the effects of D2 antagonists i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f93f326f0808b8d8cfcb51c4118cbd87
https://pubmed.ncbi.nlm.nih.gov/8807746
https://pubmed.ncbi.nlm.nih.gov/8807746
Publikováno v:
Synapse (New York, N.Y.). 22(2)
Tyrosine is a precursor in the biosynthesis of catecholamines and, when administered systemically, has been shown to enhance the in vivo rate of tyrosine hydroxylation in the medial prefrontal cortex. Additionally, exogenous tyrosine has been demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03fa0f6d642c8a8eba61f128001776bc
https://pubmed.ncbi.nlm.nih.gov/8787125
https://pubmed.ncbi.nlm.nih.gov/8787125
Autor:
John H. Fetting, R. H. Roth, Steven Piantadosi, Vivian R. Sheidler, Michael Stefanek, J. D. Elsworth
Publikováno v:
Psychosomatic medicine, vol 54, iss 6
Fetting, JH; Stefanek, ME; Sheidler, VR; Elsworth, JD; Piantadosi, S; & Roth, RH. (1992). Noradrenergic activity in anticipatory nausea. Psychosomatic Medicine, 54(6), 641-647. doi: 10.1097/00006842-199211000-00003. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6m9877td
Fetting, JH; Stefanek, ME; Sheidler, VR; Elsworth, JD; Piantadosi, S; & Roth, RH. (1992). Noradrenergic activity in anticipatory nausea. Psychosomatic Medicine, 54(6), 641-647. doi: 10.1097/00006842-199211000-00003. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6m9877td
Two studies were conducted to examine the hypothesis that noradrenergic activity is a cause of the anticipatory nausea associated with cancer chemotherapy. In the first study concentrations of plasma 3-methoxy-4- hydroxyphenyl-glycol (MHPG) on day 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c822b4a31d98a5668caca2cd1cdac322
https://escholarship.org/uc/item/6m9877td
https://escholarship.org/uc/item/6m9877td
Autor:
J D, Elsworth, M S, Lawrence, R H, Roth, J R, Taylor, R B, Mailman, D E, Nichols, M H, Lewis, D E, Redmond
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(2)
Previous studies have revealed the involvement of a dopaminergic link in the regulation of spontaneous eye blink rate in primates. Based on the effect of dopamine D2 receptor-selective drugs and the anecdotal failure of the partial D1 agonist, SKF 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a138fa19736beb704787d474dd21bce2
https://pubmed.ncbi.nlm.nih.gov/1682479
https://pubmed.ncbi.nlm.nih.gov/1682479