Zobrazeno 1 - 10
of 66
pro vyhledávání: '"J D, Ehrhardt"'
Publikováno v:
Journal of Heterocyclic Chemistry. 26:1781-1785
4-Alkyl-2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 5, 6 and 7 were obtained from 2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 1 by reaction of its anion 4 with alkyl halides. cis- and trans-Configuration of the 4-alkylated products were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99c1fff4c26ed4dc0d10b386578ae2a
https://doi.org/10.1002/jhet.5570260646
https://doi.org/10.1002/jhet.5570260646
Autor:
S. Schann, Véronique Bruban, Josiane Feldman, J. D. Ehrhardt, Pascal Bousquet, Hugues Greney, Monique Dontenwill
Publikováno v:
Annals of the New York Academy of Sciences. 881:272-278
The central hypotensive effect of imidazoline-like drugs (IMs) involves non-adrenergic imidazoline receptors (IRs). IMs cause hypotension irrespective of their affinity and selectivity for one or the other alpha-adrenoceptor subtypes. LNP 509, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3395e14abe8f5439e08f4a1cd945b4ae
https://doi.org/10.1111/j.1749-6632.1999.tb09369.x
https://doi.org/10.1111/j.1749-6632.1999.tb09369.x
Publikováno v:
Neurochemistry International. 30:9-16
Imidazoline compounds are known to interact with alpha 2-adrenoceptors as well as with specific non-adrenergic binding sites. Such binding sites are present in the brain and in peripheral tissues. Hypotensive effects of imidazolines were shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d87e994bf093bf2b3574db87fc0ee7
https://doi.org/10.1016/s0197-0186(96)00034-4
https://doi.org/10.1016/s0197-0186(96)00034-4
Autor:
J. D. Ehrhardt
Publikováno v:
Biological Mass Spectrometry. 22:295-301
Extractive methylation of clopamide and indapamide gives rise to the formation of several derivatives. Their positive and negative ion mass spectra are described and their respective structures established. This derivatization procedure seems to be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd4bed46087be74dc595c8bbc3cf26b
https://doi.org/10.1002/bms.1200220505
https://doi.org/10.1002/bms.1200220505
Autor:
J.‐D. Ehrhardt, Evelyne Grunder-Klotz
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d745db8f8b8de778f09bd6c30051ac0
https://doi.org/10.1002/chin.199220229
https://doi.org/10.1002/chin.199220229
Autor:
Evelyne Grunder-Klotz, J.‐D. Ehrhardt
Publikováno v:
ChemInform. 22
The 3,4-dimethoxybenzyl group was used to N-protect 3,4-diphenyl 1,2-thiazetidine 1,1-dioxide derivatives. It is smoothly eliminated by 2,3-dichloro 5,6-dicyanobenzoquinone (DDQ), the yield depending on the substituents of the 3-phenyl ring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::871a0da44c140d624926d83d64accbc4
https://doi.org/10.1002/chin.199151133
https://doi.org/10.1002/chin.199151133
Publikováno v:
ChemInform. 24
An advantageous one pot procedure for the synthesis of tetrahydro-1,4,3-oxathiazine 4,4-dioxides by dialkylation of readily available α,N-alkyl- or arylsulfonamide dianions with gaseous formaldehyde is reported. Stability and some reactions of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fff2e0aa611ad8d70ab591a87e9989
https://doi.org/10.1002/chin.199330199
https://doi.org/10.1002/chin.199330199
Autor:
J. D. Ehrhardt
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:725-729
The synthesis of nonadeutero-clenbuterol, a useful tool for the quantitation of clenbuterol by gas chromatography-mass spectrometry, is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c185fbc72d97e6debae8d8abccb9c73a
https://doi.org/10.1002/jlcr.2580280613
https://doi.org/10.1002/jlcr.2580280613
Autor:
Bernard Vailly, J.‐D. Ehrhardt, Jean-Louis Imbs, Michèle Grima, Jeanne Velly, Mariette Barthelmebs
Publikováno v:
American Journal of Hypertension. 3:18S-21S
In the Wistar rat in vivo L-dopa (10 mg/kg, subcutaneously) was shown to have the characteristics of a kidney-directed dopamine (DA) prodrug: two daily injections increased 24 h urinary DA excretion 450-fold but had no systemic effects on blood press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b5129332411e4acedf1f448013567b
https://doi.org/10.1093/ajh/3.6.18s
https://doi.org/10.1093/ajh/3.6.18s
Autor:
S, Schann, V, Bruban, K, Pompermayer, J, Feldman, B, Pfeiffer, P, Renard, E, Scalbert, P, Bousquet, J D, Ehrhardt
Publikováno v:
Journal of medicinal chemistry. 44(10)
To find new compounds selective for purported I1 imidazoline receptors (I1Rs) over I2 imidazoline binding sites (I2BS) and alpha2-adrenoceptors (alpha2ARs), a series of pyrrolinic isosteres of rilmenidine has been prepared and their biological activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32b4129dffdba76f8e78aa2432ed2081
https://pubmed.ncbi.nlm.nih.gov/11334568
https://pubmed.ncbi.nlm.nih.gov/11334568