Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J D, Cropper"'
Publikováno v:
British journal of pharmacology. 134(2)
1. The serotonin(2C) (5-HT(2C)) receptor couples to both phospholipase C (PLC)-inositol phosphate (IP) and phospholipase A(2) (PLA(2))-arachidonic acid (AA) signalling cascades. Agonists can differentially activate these effectors (i.e. agonist-direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::550996b2c9fb65c806b229bc884456bf
https://pubmed.ncbi.nlm.nih.gov/11564657
https://pubmed.ncbi.nlm.nih.gov/11564657
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 297(3)
The 5-hydroxytryptamine (5-HT)(1A) receptor system plays a prominent role in a variety of physiological functions and behaviors and regulation of the responsiveness of this receptor system has been implicated in the therapeutic mechanism of action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::307b52378519f7c67dcf2985a4bfe769
https://pubmed.ncbi.nlm.nih.gov/11356925
https://pubmed.ncbi.nlm.nih.gov/11356925
Publikováno v:
Molecular pharmacology. 55(5)
In cell systems where ligand-independent receptor activity is optimized (such as when receptors are overexpressed or mutated), acute treatment with inverse agonists reduces basal effector activity whereas prolonged exposure leads to sensitization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd3b37c85dd2e4af32197d8aa99f4cce
https://pubmed.ncbi.nlm.nih.gov/10220565
https://pubmed.ncbi.nlm.nih.gov/10220565