Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J D, Beggs"'
Publikováno v:
RNA (New York, N.Y.). 1(9)
Splice site recognition and catalysis of the transesterification reactions in the spliceosome are accompanied by a dynamic series of interactions involving conserved or invariant sequences in the spliceosomal snRNAs. We have used site-specific photoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7005b1d9c245354ce622e3177107555
https://pubmed.ncbi.nlm.nih.gov/8548661
https://pubmed.ncbi.nlm.nih.gov/8548661
Autor:
J. D. Beggs, M. Plumpton
Publikováno v:
Nucleic Acids and Molecular Biology ISBN: 9783642773587
Nuclear pre-mRNA splicing involves the removal from primary transcripts of internal, usually noncoding, intron sequences and joining of the protein-coding exons to produce mature mRNA. Although the majority of eukaryotic nuclear protein-encoding gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc923c69b91b0a7cdadb23dba25f1661
https://doi.org/10.1007/978-3-642-77356-3_11
https://doi.org/10.1007/978-3-642-77356-3_11
Autor:
D. J. Jamieson, J. D. Beggs
Publikováno v:
Molecular microbiology. 5(4)
The spp81/ded1 mutations were isolated as suppressors of a Saccharomyces cerevisiae pre-mRNA splicing mutation, prp8-1. The SPP81/DED1 gene encodes a putative ATP-dependent RNA helicase. While attempting to clone the wild-type SPP81/DED1 gene we isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de71c1a7e15899a0a5ebadded7e7ec08
https://pubmed.ncbi.nlm.nih.gov/1857205
https://pubmed.ncbi.nlm.nih.gov/1857205
Publikováno v:
Nature. 349(6311)
Five small nuclear RNAs (snRNAs) are required for nuclear pre-messenger RNA splicing: U1, U2, U4, U5 and U6. The yeast U1 and U2 snRNAs base-pair to the 5' splice site and branch-point sequences of introns respectively. The role of the U5 and U4/U6 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47b795b808e16bbdb46713535894b934
https://pubmed.ncbi.nlm.nih.gov/1996139
https://pubmed.ncbi.nlm.nih.gov/1996139
Publikováno v:
Cancer research. 50(24)
Mitomycin C is an alkylating agent used in cancer chemotherapy that shows some specificity towards hypoxic cells. The therapeutic effects of this compound are thought to result from its metabolic activation by enzymes such as NADPH:cytochrome P-450 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::246e0648f0553053cc640fff90d2081d
https://pubmed.ncbi.nlm.nih.gov/2123741
https://pubmed.ncbi.nlm.nih.gov/2123741
Autor:
J. D. Beggs, Penny R. Hirsch
Publikováno v:
Molecular and General Genetics MGG. 195:209-214
A section of the octopine Ti plasmid pTiACH5 including the region always integrated in crown gall tumour cells (the TL-DNA) was cloned into the yeast — E. coli shuttle vector pJDB207. This plasmid, pOTY8, was transformed into S. cerevisiae where tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9187cb8b148d2ce5a654c0652aa42aa
https://doi.org/10.1007/bf00332748
https://doi.org/10.1007/bf00332748
Publikováno v:
The EMBO Journal. 3:2825-2830
The RNA2 gene of Saccharomyces cerevisiae, which has been implicated in splicing the transcripts of nuclear protein coding genes, has been cloned by complementation of the temperature-sensitive growth defect of an rna2-1 mutant strain. The cloned seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489fc56ea43dc3779cfd2199abbec43c
https://doi.org/10.1002/j.1460-2075.1984.tb02215.x
https://doi.org/10.1002/j.1460-2075.1984.tb02215.x
Publikováno v:
Molecular and cellular biology. 9(9)
The PRP4 (RNA4) gene product is involved in nuclear mRNA processing in yeast cells; we have previously cloned the gene by complementation of a temperature-sensitive mutation. Sequence and transcript analyses of the cloned gene predicted the gene prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e2a916498b2792074d6ae08e29152f
https://pubmed.ncbi.nlm.nih.gov/2528686
https://pubmed.ncbi.nlm.nih.gov/2528686