Zobrazeno 1 - 10
of 46
pro vyhledávání: '"J D, Ansell"'
Autor:
Robert A.J. Oostendorp, Kay Samuel, J. D. Ansell, Sabrina Gordon-Keylock, Derek S. Gilchrist, Lesley M. Forrester, Anna Krassowska, Elaine Dzierzak
Publikováno v:
Experimental Cell Research, 312(18), 3595-3603. Elsevier Inc.
We investigated whether the in vitro differentiation of ES cells into haematopoietic progenitors could be enhanced by exposure to the aorta-gonadal-mesonephros (AGM) microenvironment that is involved in the generation of haematopoietic stem cells (HS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0610a4c2e7fc19cec9aee28ef7958766
https://doi.org/10.1016/j.yexcr.2006.08.001
https://doi.org/10.1016/j.yexcr.2006.08.001
Autor:
Timothy Chevassut, Nick Gilbert, Anna Krassowska, Lesley M. Forrester, Bernard Ramsahoye, Melany Jackson, J. D. Ansell
Publikováno v:
Molecular and Cellular Biology. 24:8862-8871
It has been reported that DNA methyltransferase 1-deficient (Dnmt1−/−) embryonic stem (ES) cells are hypomethylated (20% CpG methylation) and die through apoptosis when induced to differentiate. Here, we show that Dnmt[3a−/−,3b−/−] ES cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e234db257ff92928975eadbb072cfd
https://doi.org/10.1128/mcb.24.20.8862-8871.2004
https://doi.org/10.1128/mcb.24.20.8862-8871.2004
Autor:
J. D. Ansell
Publikováno v:
European Journal of Cancer. 40:1945-1950
In his 1965 paper 'DNA content of tumours: cytophotometric measurements', Sandritter was for the first time able to relate tumour DNA content to the pathology and progression of a small number of tumours. In subsequent publications, these observation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e11acf5a28d51719b54fec2e693faf5
https://doi.org/10.1016/j.ejca.2004.01.043
https://doi.org/10.1016/j.ejca.2004.01.043
Autor:
Lesley M. Forrester, J. D. Ansell, Jennifer Nichols, Janet W. Baird, Melany Jackson, Gerry Graham, Ron Wilkie
Publikováno v:
Developmental Dynamics. 228:740-744
Ehox is an X-linked paired like homeobox gene identified from a differentiating embryonic stem (ES) cell cDNA library and is expressed at low levels in the preimplantation blastocyst and in ES cells in vitro. In embryos at 6.5 days post coitum (dpc),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6661e673d54c8fdf2ab933352dca48f
https://doi.org/10.1002/dvdy.10413
https://doi.org/10.1002/dvdy.10413
Publikováno v:
Immunology today. 5(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336203192ba00b1f1df1f210c5c00462
https://pubmed.ncbi.nlm.nih.gov/25290749
https://pubmed.ncbi.nlm.nih.gov/25290749
Autor:
Kay Samuel, Mary G. Freshney, Eric G. Wright, Ian B. Pragnell, Tessa L. Holyoake, Gwyneth E. Watson, Gerard J. Graham, J. D. Ansell
Publikováno v:
British Journal of Haematology. 114:49-56
Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5+ B cells. This B-cell lineage is established during ontogeny and replenished by the process of self-renewal. Spontaneous and induced leukaemias that frequently affect this lineage are thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d425ef0429c892858d25faa1e8dffc
https://doi.org/10.1046/j.1365-2141.2001.02903.x
https://doi.org/10.1046/j.1365-2141.2001.02903.x
Autor:
Martha Wootton, Ian Hayes, Gerard J. Graham, Kevin M. Ryan, Lynne Hampson, Janet W. Baird, Clare M. Heyworth, J. D. Ansell, Andrew R. Clark, Nicholas Hole, Ursula Menzel
Publikováno v:
Journal of Biological Chemistry. 276:9189-9198
The difficulties associated with studying molecular mechanisms important in hemopoietic stem cell (HSC) function such as the problems of purifying homogeneous stem cell populations, have prompted us to adapt the murine ES cell system as an in vitro m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1eb7b80438bd85f029761e2de811921
https://doi.org/10.1074/jbc.m008354200
https://doi.org/10.1074/jbc.m008354200
Publikováno v:
Europe PubMed Central
Embryonal stem cells have been shown to differentiate in vitro into all hematopoietic lineages. This has been used successfully as one approach to the study of genetic events occurring during haematopoiesis. However, studies on the commitment of meso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708f406a04558fbbff3e4947cdaf91c7
https://doi.org/10.1182/blood.v88.4.1266.bloodjournal8841266
https://doi.org/10.1182/blood.v88.4.1266.bloodjournal8841266
Publikováno v:
Development. 118:859-863
The basis of a previously observed difference in the level of contribution of hypoxanthine phosphoribosyltrans-ferase-deficient cells between the haematopoietic and non-haematopoietic tissues of chimaeric and heterozy-gous mice has been clarified by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712c10d4bd105a045eef7cb90059ad83
https://doi.org/10.1242/dev.118.3.859
https://doi.org/10.1242/dev.118.3.859
Publikováno v:
The Journal of Pathology. 168:335-342
We describe a polycystic lesion of the kidney in the CBA/N mouse with an X-linked recessive immunodeficient syndrome. There is progressive cystic dilatation affecting all parts of the nephron. The cyst lining is composed of a single layered epitheliu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439b78e85db0b379e65076ed0d91559b
https://doi.org/10.1002/path.1711680315
https://doi.org/10.1002/path.1711680315