Výsledky vyhledávání

Fragility of results from randomized controlled trials supporting the guidelines for the treatment of osteoporosis: a retrospective analysis

Autor: X, Huang, B, Chen, L, Thabane, J D, Adachi, G, Li

Publikováno v: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 32(9)

This is the first report on the fragility of results from randomized controlled trials (RCTs) for the treatment of osteoporosis. The results of aforementioned RCTs appear to depend on a small number of events and are generally statistically fragile.O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bbac5f469ab2d1d70374ad91869e498e
https://pubmed.ncbi.nlm.nih.gov/33595680

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Exploring changes in bone mass in individuals with a chronic spinal cord injury

Autor: R, El-Kotob, B C, Craven, L, Thabane, A, Papaioannou, J D, Adachi, L M, Giangregorio

People experience rapid bone loss shortly after a spinal cord injury (SCI), but the long-term bone changes are yet to be confirmed. This study showed that trabecular bone may have reached a steady state, whereas cortical bone continued to decline in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e334f3d78fdcda96e00bb43781392084
https://pubmed.ncbi.nlm.nih.gov/33089353

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Advanced 2D image processing technique to predict hip fracture risk in an older population based on single DXA scans

Autor: F, Jazinizadeh, J D, Adachi, C E, Quenneville

A new technique to enhance hip fracture risk prediction in older adults was presented and assessed. The new method dramatically improved prediction at high specificity levels using only a standard clinical diagnostic scan. This has the potential to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ddebd2dbd3c470aa1a25c6e412f6e01d
https://pubmed.ncbi.nlm.nih.gov/34665290

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Build better bones with exercise (B3E pilot trial): results of a feasibility study of a multicenter randomized controlled trial of 12 months of home exercise in older women with vertebral fracture

Autor: L M, Giangregorio, J C, Gibbs, J A, Templeton, J D, Adachi, M C, Ashe, R R, Bleakney, A M, Cheung, K D, Hill, D L, Kendler, A A, Khan, S, Kim, C, McArthur, N, Mittmann, A, Papaioannou, S, Prasad, S C, Scherer, L, Thabane, J D, Wark

We pilot-tested a trial of home exercise on individuals with osteoporosis and spine fracture. Our target enrollment was met, though it took longer than expected. Participants stayed in the study and completed the exercise program with no safety conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04d568779e71fd922db430a3bbe504c6
https://pubmed.ncbi.nlm.nih.gov/30091064

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Estrogen-progestin therapy causes a greater increase in spinal bone mineral density than estrogen therapy - a systematic review and meta-analysis of controlled trials with direct randomization

Autor: J C, Prior, V R, Seifert-Klauss, D, Giustini, J D, Adachi, S, Kalyan, A, Goshtasebi

Publikováno v: Journal of Musculoskeletal & Neuronal Interactions

Objective: To assess whether progesterone (P4) or osteoblast P4 receptor-acting progestin (P) contributed to estrogen (E) therapy-related increased areal bone mineral density (BMD) in randomized controlled trials (RCT) with direct randomization to es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fe854a6dd5824b9c645f2283e2252df4
https://pubmed.ncbi.nlm.nih.gov/28860416

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The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis

Autor: A, Kalani, H, Bami, M, Tiboni, R, Jaeschke, J D, Adachi, A N, Lau

Publikováno v: Obesity Science & Practice

Summary Background Concerns have emerged about post‐operative decreases in calcium and vitamin D following bariatric surgery. This review explores changes in metabolic bone health in persons with obesity undergoing gastric bypass surgery compared t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a31357cd1bc12a1241f5aa84380321c3
https://pubmed.ncbi.nlm.nih.gov/29071108

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Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study

Autor: S L, Silverman, A A, Chines, D L, Kendler, A W C, Kung, C S, Teglbjærg, D, Felsenberg, N, Mairon, G D, Constantine, J D, Adachi, Edward, Zbella

Publikováno v: Osteoporosis International, 23(1), 351-363. Springer-Verlag London Ltd.

In this 2-year extension of a 3-year study, bazedoxifene showed sustained efficacy in preventing new vertebral fractures in postmenopausal women with osteoporosis and in preventing non-vertebral fractures in higher-risk women. Bazedoxifene significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf83d1c6a18f1ef005528eb50c1929d
https://doi.org/10.1007/s00198-011-1691-1

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Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study

Autor: L-A, Fraser, G, Ioannidis, J D, Adachi, L, Pickard, S M, Kaiser, J, Prior, J P, Brown, D A, Hanley, W P, Olszynski, T, Anastassiades, S, Jamal, R, Josse, D, Goltzman, A, Papaioannou, Brian, Lentle

Publikováno v: Osteoporosis International. 22:789-796

Canadian women over 50 years old were studied over a 10-year period to see if those who sustained a fracture (caused by minimal trauma) were receiving the recommended osteoporosis therapy. We found that approximately half of these women were not bein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22909e258cd4279e3068f7bcf35c28f
https://doi.org/10.1007/s00198-010-1359-2

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