Zobrazeno 1 - 10
of 138
pro vyhledávání: '"J Crawford Downs"'
Autor:
Alireza Karimi, Mahdi Halabian, Reza Razaghi, J. Crawford Downs, Mary J. Kelley, Ted S. Acott
Publikováno v:
Cells, Vol 11, Iss 23, p 3925 (2022)
A layer of proteoglycans and glycoproteins known as glycocalyx covers the surface of the trabecular meshwork (TM), juxtacanalicular tissue (JCT), and Schlemm’s canal (SC) inner wall of the conventional aqueous outflow pathway in the eye. This has b
Externí odkaz:
https://doaj.org/article/0a4fc3dea1294b04aec0c1b349dea016
Autor:
Alireza Karimi, Reza Razaghi, Seyed Mohammadali Rahmati, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Ruikang K. Wang, Murray Johnstone
Publikováno v:
Bioengineering, Vol 9, Iss 11, p 672 (2022)
Background: Aqueous humor outflow resistance in the trabecular meshwork (TM), juxtacanalicular connective tissue (JCT), and Schlemm’s canal (SC) endothelium of the conventional outflow pathway actively contribute to intraocular pressure (IOP) regul
Externí odkaz:
https://doaj.org/article/086c1b2f973941c691d204e632894c3c
Autor:
J. Crawford Downs, David Fleischman
Publikováno v:
Ophthalmology Glaucoma. 5:465-467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e5b3fdd056feaaacd4ca1e404519b9
https://doi.org/10.1016/j.ogla.2022.02.008
https://doi.org/10.1016/j.ogla.2022.02.008
Publikováno v:
Injury
BACKGROUND: Eye injuries comprise 10–13% of civilian improvised explosive device (IED) injuries. The bomb blast wave induces a normal and shear forces on the tissues, causing a large acute IOP elevation. This study calculated the biomechanical stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba8a40fe55c37b36fc20c7e5a793825
https://doi.org/10.1016/j.injury.2022.02.008
https://doi.org/10.1016/j.injury.2022.02.008
Autor:
Christopher A. Girkin, Rafael Grytz, Seyed Mohammadali Rahmati, Alireza Karimi, J. Crawford Downs
Publikováno v:
Acta Biomater
Glaucoma is among the leading causes of blindness worldwide that is characterized by irreversible damage to the retinal ganglion cell axons in the lamina cribrosa (LC) region of the optic nerve head (ONH), most often associated with elevated intraocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817e5f172b495c285184c64b4a3bc667
https://doi.org/10.1016/j.actbio.2021.07.010
https://doi.org/10.1016/j.actbio.2021.07.010
Autor:
Alireza Karimi, Reza Razaghi, Steven Padilla, Seyed Mohammadali Rahmati, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Ruikang K. Wang, Murray Johnstone
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 20; Pages: 6049
Background: Although the tissues comprising the ocular conventional outflow pathway have shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the viscoelastic mechanical properties of the trabecular meshwork (TM), juxtaca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f68c3ac394501ba3a587f750f4323ba
https://pubmed.ncbi.nlm.nih.gov/36294371
https://pubmed.ncbi.nlm.nih.gov/36294371
Autor:
John E. Markert, Daniel C. Turner, Jessica V. Jasien, Cyril N. A. Nyankerh, Brian C. Samuels, J. Crawford Downs
Publikováno v:
Translational vision sciencetechnology. 11(9)
The purpose of this study was to assess ocular coat mechanical behavior using controlled ocular microvolumetric injections (MVI) of 15 µL of balanced salt solution (BSS) infused over 1 second into the anterior chamber (AC) via a syringe pump.Intraoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceda6c4b22be3589399cd1b8f54ee9fb
https://pubmed.ncbi.nlm.nih.gov/36074454
https://pubmed.ncbi.nlm.nih.gov/36074454
Autor:
Alireza Karimi, Devon J. Crouch, Reza Razaghi, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Julia G. Behnsen, Lucy A. Bosworth, Carl M. Sheridan
Publikováno v:
Computer Methods and Programs in Biomedicine. 236:107485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aec308b7c18aa3dfee70098b67398fb
https://doi.org/10.1016/j.cmpb.2023.107485
https://doi.org/10.1016/j.cmpb.2023.107485
Autor:
Alireza Karimi, Seyed Mohammadali Rahmati, Reza Razaghi, Christopher A. Girkin, J. Crawford Downs
Publikováno v:
Comput Methods Programs Biomed
BACKGROUND AND OBJECTIVE: Accurate finite element (FE) simulation of the optic nerve head (ONH) depends on accurate mechanical properties of the load-bearing tissues. The peripapillary sclera in the ONH exhibits a depth-dependent, anisotropic, hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77e947e240dcc014d9eb6fa7c3f184c
https://europepmc.org/articles/PMC8847341/
https://europepmc.org/articles/PMC8847341/
Autor:
Alireza Karimi, Reza Razaghi, Seyed Mohammadali Rahmati, Christopher A. Girkin, J. Crawford Downs
Publikováno v:
Investigative Opthalmology & Visual Science. 63:14
The laminar region of the optic nerve head (ONH), thought to be the site of damage to the retinal ganglion cell axons in glaucoma, is continuously loaded on its anterior and posterior surfaces by dynamic intraocular pressure (IOP) and orbital cerebro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31ed84c8c5d5ed8ff7c4eb536d97cbc
https://doi.org/10.1167/iovs.63.11.14
https://doi.org/10.1167/iovs.63.11.14