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Akademický článek

Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide

Autor: Adam C. Mirando, Akash Patil, Christine I. Rafie, Brian J. Christmas, Niranjan B. Pandey, Vered Stearns, Elizabeth M. Jaffee, Evanthia T. Roussos Torres, Aleksander S. Popel

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)

Triple-negative breast cancer (TNBC) is a highly metastatic and aggressive disease with limited treatment options. Recently, the combination of the immune checkpoint inhibitor (ICI) atezolizumab (anti-PD-L1) with nab-paclitaxel was approved following

Externí odkaz: https://doaj.org/article/d7ce52b28cfc47f195f57a6014ece82b

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Akademický článek

Genomic, Habitat, and Leaf Shape Analyses Reveal a Possible Cryptic Species and Vulnerability to Climate Change in a Threatened Daisy

Autor: Colette Blyth, Matthew J. Christmas, Douglas C. Bickerton, Martin F. Breed, Nicole R. Foster, Greg R. Guerin, Alex R. G. Mason, Andrew J. Lowe

Publikováno v: Life, Vol 11, Iss 6, p 553 (2021)

Olearia pannosa is a plant species listed as vulnerable in Australia. Two subspecies are currently recognised (O. pannosa subsp. pannosa (silver daisy) and O. pannosa subsp. cardiophylla (velvet daisy)), which have overlapping ranges but distinct lea

Externí odkaz: https://doaj.org/article/8a745a9c8e304e6da5e3b44dc6390432

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Supplementary Data from Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment

Supplementary Data from Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e28169c16cf94af543790c359b314a
https://doi.org/10.1158/2326-6066.22544265.v1

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Supplementary Tables from Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs

Autor: Evanthia T. Roussos Torres, Elizabeth M. Jaffee, Nilo A. Azad, Roisin M. Connolly, Todd D. Armstrong, Skylar Woolman, Kayla A. Cruz, Hayley S. Ma, Blake A. Scott, Alexander C. Hopkins, Christine I. Rafie, Brian J. Christmas

The supplemental tables include: antibodies used for flow cytometry; gene expression of genes involved in innate and adaptive immunity from whole tumors isolated from neu-N mice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bd3a23d62a3fdb27f3502630a400bf
https://doi.org/10.1158/2326-6066.22538896

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Supplementary Figures S1-S11 from Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs

This file contains supplemental figures that includes: FACS gating strategies; QC plots for NanoString cell typing; survival and tumor growth of neu-N mice receiving ENT and ICIs without ï�¡-HER2; circulating MDSCs and absolute numbers of G-MDSCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5561698696205b6427f8b02775c68e
https://doi.org/10.1158/2326-6066.22538899.v1

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Data from Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs

Immune-checkpoint inhibition (ICI) has revolutionized treatment in cancers that are naturally immunogenic by enabling infiltration of T cells into the tumor microenvironment (TME) and promoting cytotoxic signaling pathways. Tumors possessing complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e252e85b4ea5bba5580656a736573b9
https://doi.org/10.1158/2326-6066.c.6548935.v1

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Supplementary Figure legends from Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs

Supplementary figure legends (S1-S11) clean AND supplementary table legends (1-2) clean.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a1ecb99bc3175db58fdb19be563c9c
https://doi.org/10.1158/2326-6066.22538902.v1

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Akademický článek

Increased Genetic Diversity via Gene Flow Provides Hope for Acacia whibleyana, an Endangered Wattle Facing Extinction

Autor: Colette Blyth, Matthew J. Christmas, Doug C. Bickerton, Renate Faast, Jasmin G. Packer, Andrew J. Lowe, Martin F. Breed

Publikováno v: Diversity, Vol 12, Iss 8, p 299 (2020)

In this paper we apply a conservation genomics approach to make evidence-based management recommendations for Acacia whibleyana, an endangered shrub endemic to Eyre Peninsula, South Australia. We used population genomic analysis to assess genetic con

Externí odkaz: https://doaj.org/article/fc9a2c25cd5c4ab78edf40bb0aacf5aa

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