Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J Chris Vos"'
Autor:
Angelina Huseinovic, Jolanda S van Leeuwen, Tibor van Welsem, Iris Stulemeijer, Fred van Leeuwen, Nico P E Vermeulen, Jan M Kooter, J Chris Vos
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173573 (2017)
Acetaminophen (APAP), although considered a safe drug, is one of the major causes of acute liver failure by overdose, and therapeutic chronic use can cause serious health problems. Although the reactive APAP metabolite N-acetyl-p-benzoquinoneimine (N
Externí odkaz:
https://doaj.org/article/65f73057d6b14542bc67ed34df520912
Autor:
Hanna Westbroek, Marco Siderius, Danny J. Scholten, Erik J. J. Boon, Stefan J. Dekker, Jacqueline E. van Muijlwijk-Koezen, J. Chris Vos, Anna H. Vuuregge, Maikel Wijtmans
Publikováno v:
Scholten, D J, Wijtmans, M, Dekker, S J, Vuuregge, A H, Boon, E J J, Vos, J C, Siderius, M, Westbroek, H & Van Muijlwijk-Koezen, J E 2021, ' Practical Guidelines to Redesign Introductory Chemistry Courses Using a Flexible and Adaptive Blended Format ', Journal of Chemical Education, vol. 98, no. 12, pp. 3852-3863 . https://doi.org/10.1021/acs.jchemed.1c00644
Journal of Chemical Education, 98(12), 3852-3863. American Chemical Society
Journal of Chemical Education, 98(12), 3852-3863. American Chemical Society
Incorporation of increased flexibility and adaptivity in courses can support freshmen with taking responsibility for their learning process. This is especially beneficial in the case of chemistry courses given their typically abstract nature and asso
Autor:
Dzjemma Sarkisjan, Godefridus J. Peters, Btissame El Hassouni, Elisa Giovannetti, J. Chris Vos
Publikováno v:
Current Medicinal Chemistry, 26(33), 6020-6032. Bentham Science Publishers B.V.
El Hassouni, B, Sarkisjan, D, Vos, J C, Giovannetti, E & Peters, G J 2019, ' Targeting the ribosome biogenesis key molecule fibrillarin to avoid chemoresistance ', Current Medicinal Chemistry, vol. 26, no. 33, pp. 6020-6032 . https://doi.org/10.2174/0929867326666181203133332
el Hassouni, B, Sarkisjan, D, Vos, J C, Giovannetti, E & Peters, G J 2019, ' Targeting the Ribosome Biogenesis Key Molecule Fibrillarin to Avoid Chemoresistance ', Current Medicinal Chemistry, vol. 26, no. 33, pp. 6020-6032 . https://doi.org/10.2174/0929867326666181203133332
El Hassouni, B, Sarkisjan, D, Vos, J C, Giovannetti, E & Peters, G J 2019, ' Targeting the ribosome biogenesis key molecule fibrillarin to avoid chemoresistance ', Current Medicinal Chemistry, vol. 26, no. 33, pp. 6020-6032 . https://doi.org/10.2174/0929867326666181203133332
el Hassouni, B, Sarkisjan, D, Vos, J C, Giovannetti, E & Peters, G J 2019, ' Targeting the Ribosome Biogenesis Key Molecule Fibrillarin to Avoid Chemoresistance ', Current Medicinal Chemistry, vol. 26, no. 33, pp. 6020-6032 . https://doi.org/10.2174/0929867326666181203133332
Background: Inherent or acquired chemo resistance in cancer patients has been a perpetual limitation in cancer treatment. Expanding knowledge on essential cellular processes opens a new window for therapeutic targeting. Ribosome biogenesis is a proce
Autor:
Bob Boogaard, Stefan J. Dekker, J. Chris Vos, Angelina Huseinovic, Jan M. Kooter, Nico P. E. Vermeulen
Publikováno v:
Amino Acids
Huseinovic, A, Dekker, S J, Boogaard, B, Vermeulen, N P E, Kooter, J M & Vos, J C 2018, ' Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion ', Amino Acids, vol. 50, no. 10, pp. 1377-1390 . https://doi.org/10.1007/s00726-018-2613-8
Amino Acids, 50(10), 1377-1390. Springer Wien
Huseinovic, A, Dekker, S J, Boogaard, B, Vermeulen, N P E, Kooter, J M & Vos, J C 2018, ' Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion ', Amino Acids, vol. 50, no. 10, pp. 1377-1390 . https://doi.org/10.1007/s00726-018-2613-8
Amino Acids, 50(10), 1377-1390. Springer Wien
In yeast, toxicity of acetaminophen (APAP), a frequently used analgesic and antipyretic drug, depends on ubiquitin-controlled processes. Previously, we showed a remarkable overlap in toxicity profiles between APAP and tyrosine, and a similarity with
Autor:
Stephanie van Leeuwen, Stefan J. Dekker, Shalenie P. den Braver-Sewradj, Robin M. Toorneman, Michiel W. den Braver, Nico P. E. Vermeulen, Yongjie Zhang, Jan N. M. Commandeur, J. Chris Vos
Publikováno v:
den Braver-Sewradj, S P, den Braver, M W, Toorneman, R M, Van Leeuwen, S, Zhang, Y, Dekker, S J, Vermeulen, N P E, Commandeur, J N M & Vos, J C 2018, ' Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H : Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations ', Chemical Research in Toxicology, vol. 31, no. 2, pp. 116-126 . https://doi.org/10.1021/acs.chemrestox.7b00289
Chemical Research in Toxicology
Chemical Research in Toxicology, 31(2), 116-126. American Chemical Society
Chemical Research in Toxicology
Chemical Research in Toxicology, 31(2), 116-126. American Chemical Society
Detoxicating enzymes NAD(P)H:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2) catalyze the two-electron reduction of quinone-like compounds. The protective role of the polymorphic NQO1 and NQO2 enzymes is especially of interest
Autor:
Jan M. Kooter, Jolanda van Leeuwen, Fred van Leeuwen, Angelina Huseinovic, Nico P. E. Vermeulen, Iris J. E. Stulemeijer, J. Chris Vos, Tibor van Welsem
Publikováno v:
Huseinovic, A, van Leeuwen, J, van Welsem, T, Stulemeijer, I, van Leeuwen, F, Vermeulen, N P E, Kooter, J M & Vos, J C 2017, ' The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae ', PLoS ONE, vol. 12, no. 3, e0173573, pp. 1-19 . https://doi.org/10.1371/journal.pone.0173573
PLoS ONE, 12(3):e0173573. Public Library of Science
PLoS ONE
PLoS ONE, 12(3):e0173573, 1-19. Public Library of Science
PLoS ONE, Vol 12, Iss 3, p e0173573 (2017)
PLoS ONE, 12(3):e0173573. Public Library of Science
PLoS ONE
PLoS ONE, 12(3):e0173573, 1-19. Public Library of Science
PLoS ONE, Vol 12, Iss 3, p e0173573 (2017)
Acetaminophen (APAP), although considered a safe drug, is one of the major causes of acute liver failure by overdose, and therapeutic chronic use can cause serious health problems. Although the reactive APAP metabolite N-acetyl-p-benzoquinoneimine (N
Autor:
Heidi Foth, Marc C. Jochimsen, J. Chris Vos, Sanja Dragovic, Ole J. Bjerrum, Jorgen Dirach, Jan Wiese
Publikováno v:
European Journal of Pharmaceutical Sciences. 96:III-VIII
Autor:
Jan N. M. Commandeur, Yongjie Zhang, J. Chris Vos, Shalenie P. den Braver-Sewradj, Nico P. E. Vermeulen
Publikováno v:
Zhang, Y, den Braver-Sewradj, S P, Vos, J C, Vermeulen, N P E & Commandeur, J N M 2017, ' Human glutathione S-transferases-and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine : Possible implications for susceptibility to amodiaquine-induced liver toxicity ', Toxicology Letters, vol. 275, pp. 83-91 . https://doi.org/10.1016/j.toxlet.2017.05.003
Toxicology Letters, 275, 83-91. Elsevier BV
Toxicology Letters, 275, 83-91. Elsevier BV
Amodiaquine (AQ), an antimalarial drug, widely prescribed in endemic areas of Africa and Asia, is used in combination with artesunate as recommended by the WHO. However, due to its idiosyncratic hepatotoxicity and agranulocytosis, the therapeutic use
From Face-to-Face training to blended learning in the postgraduate program SafeSciMET - a case study
Autor:
J. Chris Vos, Sanja Dragovic, Marc Jochimsen, Jorgen Dirach, Heidi Foth, Jan Wiese, Bjerrum, Ole J.
Publikováno v:
Vrije Universiteit Amsterdam
European Journal of Pharmaceutical Sciences, 96, III-VIII. Elsevier
Vos, J C, Dragovic, S, Jochimsen, M, Dirach, J, Foth, H, Wiese, J & Bjerrum, O J 2017, ' From Face-to-Face training to blended learning in the postgraduate program SafeSciMET-a case study ', European Journal of Pharmaceutical Sciences, vol. 96, pp. III-VIII .
European Journal of Pharmaceutical Sciences, 96, III-VIII. Elsevier
Vos, J C, Dragovic, S, Jochimsen, M, Dirach, J, Foth, H, Wiese, J & Bjerrum, O J 2017, ' From Face-to-Face training to blended learning in the postgraduate program SafeSciMET-a case study ', European Journal of Pharmaceutical Sciences, vol. 96, pp. III-VIII .
Autor:
Maikel Boot, Jan N. M. Commandeur, J. Chris Vos, Sandra Ortega Ugalde, Paul Jennings, Wilbert Bitter
Publikováno v:
Ortega Ugalde, S, Boot, M, Commandeur, J N M, Jennings, P, Bitter, W & Vos, J C 2019, ' Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets? ', Applied Microbiology and Biotechnology, vol. 103, no. 9, pp. 3597-3614 . https://doi.org/10.1007/s00253-019-09697-z
Applied Microbiology and Biotechnology, 103(9), 3597-3614. Springer Verlag
Applied Microbiology and Biotechnology, 103(9), 3597-3614. Springer Verlag
This review covers the current knowledge of the cytochrome P450 enzymes (CYPs) of the human pathogen Mycobacterium tuberculosis (Mtb) and their endogenous redox partners, focusing on their biological function, expression, regulation, involvement in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e2d2ef4f32e4ef20a57cdcc4b44436
https://research.vumc.nl/en/publications/9e189f5d-4ee2-4ee3-9ec7-a35e721b56ba
https://research.vumc.nl/en/publications/9e189f5d-4ee2-4ee3-9ec7-a35e721b56ba