Zobrazeno 1 - 10
of 75
pro vyhledávání: '"J Ching, Lee"'
Autor:
Michal R. Szymanski, Wangsheng Yu, Aleksandra M. Gmyrek, Mark A. White, Ian J. Molineux, J. Ching Lee, Y. Whitney Yin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Human EXOG is crucial for mitochondrial DNA repair. Here the authors present the crystal structures of hEXOG in apo form and as DNA complex and suggest a `tape-measure' activity to generate optimal substrates for mitochondrial base excision repair.
Externí odkaz:
https://doaj.org/article/69b2fef277bd4fcea402f22d42c7215c
Autor:
James Knapp, Alexandre Esadze, Mark A. White, J. Ching Lee, Wilfredo Evangelista, Alexey V. Gribenko, Levani Zandarashvili
Publikováno v:
Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Academico-UPC
UPC-Institucional
Universidad Peruana de Ciencias Aplicadas
instacron:UPC
Biochemistry
Repositorio Academico-UPC
UPC-Institucional
Universidad Peruana de Ciencias Aplicadas
instacron:UPC
Biochemistry
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. During the life cycle of enteric bacterium Escherichia coli, it encounters a wide spectrum of pH ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e629120cf0c918019dee7d6bc7140cab
https://doi.org/10.1021/acs.biochem.1c00388
https://doi.org/10.1021/acs.biochem.1c00388
Autor:
Wilfredo, Evangelista, James, Knapp, Levani, Zandarashvili, Alexandre, Esadze, Mark A, White, Alexey V, Gribenko, J Ching, Lee
Publikováno v:
Biochemistry. 60(40)
During the life cycle of enteric bacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faf5b13e6734c9c4e89ee1713eaf194e
https://pubmed.ncbi.nlm.nih.gov/34605636
https://pubmed.ncbi.nlm.nih.gov/34605636
Publikováno v:
Biochemistry. 59:460-470
The theory for allostery has evolved to a modern Energy Landscape Ensemble Theory, the major feature of which is the existence of multiple microstates in equilibrium. The properties of microstates are not well defined due to their transient nature. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24fcca5b9b0d88167603c7af312d80dc
https://doi.org/10.1021/acs.biochem.9b00895
https://doi.org/10.1021/acs.biochem.9b00895
Publikováno v:
J Biol Chem
The Escherichia coli cAMP receptor protein, CRP, is a homodimeric global transcription activator that employs multiple mechanisms to modulate the expression of hundreds of genes. These mechanisms require different interfacial interactions among CRP,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd06db224ff7ab3873d3e029b639d59
https://doi.org/10.1074/jbc.ra119.009151
https://doi.org/10.1074/jbc.ra119.009151
Publikováno v:
Biochemistry. 59(4)
The theory for allostery has evolved to a modern energy landscape ensemble theory, the major feature of which is the existence of multiple microstates in equilibrium. The properties of microstates are not well defined due to their transient nature. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::684cae92bb3e8dc2037db6e78c46f067
https://pubmed.ncbi.nlm.nih.gov/31885251
https://pubmed.ncbi.nlm.nih.gov/31885251
Autor:
J. Ching Lee, Rodrigo A. Maillard, Vincent J. Hilser, Tong Liu, David W.C. Beasley, Alan D.T. Barrett
Publikováno v:
Journal of the American Chemical Society
Mutations in the epitopes of antigenic proteins can confer viral resistance to antibody-mediated neutralization. However, the fundamental properties that characterize epitope residues and how mutations affect antibody binding to alter virus susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007a0b612f33c6379462b4ea1b0dbfdd
https://doi.org/10.1021/ja503318x
https://doi.org/10.1021/ja503318x
Autor:
Wangsheng Yu, Y. Whitney Yin, Mark A. White, Ian J. Molineux, J. Ching Lee, Michal R. Szymanski, Aleksandra M. Gmyrek
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Human EXOG (hEXOG) is a 5′-exonuclease that is crucial for mitochondrial DNA repair; the enzyme belongs to a nonspecific nuclease family that includes the apoptotic endonuclease EndoG. Here we report biochemical and structural studies of hEXOG, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6f8c13c9df0a25f1a8f5881a81c881
https://pubmed.ncbi.nlm.nih.gov/28466855
https://pubmed.ncbi.nlm.nih.gov/28466855
Autor:
Petr Herman, J. Ching Lee
Publikováno v:
Biochemistry. 48:9456-9465
The energetic landscape of the allosteric regulatory mechanism of rabbit muscle pyruvate kinase (RMPK) was characterized by isothermal titration calorimetry (ITC). Four novel insights were uncovered. (1) ADP exhibits a dual property. Depending on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5163eb1fbc1de17d36fcf6ebc288d62a
https://doi.org/10.1021/bi900280u
https://doi.org/10.1021/bi900280u
Autor:
Petr Herman, J. Ching Lee
Publikováno v:
Biochemistry. 48:9466-9470
Mammalian pyruvate kinase exists in four isoforms with characteristics tuned to specific metabolic requirements of different tissues. All of the isoforms, except the muscle isoform, exhibit typical allosteric behavior. The case of the muscle isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac6646b9ab6e40f7c26043c41f7b3be
https://doi.org/10.1021/bi900281s
https://doi.org/10.1021/bi900281s