Zobrazeno 1 - 10
of 2 678
pro vyhledávání: '"J Chamberlain"'
Autor:
Tuan V. Nguyen, Sunduimijid Bolormaa, Coralie M. Reich, Amanda J. Chamberlain, Christy J. Vander Jagt, Hans D. Daetwyler, Iona M. MacLeod
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-14 (2024)
Abstract Background Genotype imputation is a cost-effective method for obtaining sequence genotypes for downstream analyses such as genome-wide association studies (GWAS). However, low imputation accuracy can increase the risk of false positives, so
Externí odkaz:
https://doaj.org/article/e626f943e7ba479aafdd42173336d620
Autor:
Tumaini Rucker Coker, Emily F. Gregory, Mary McCord, Rushina Cholera, Hayes Bakken, Steve Chapman, Eimaan Anwar, Jennifer Lee, Shauntée Henry, Lisa J. Chamberlain
Publikováno v:
BMC Primary Care, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract This statement from the Pediatric Academic Societies Maternal Child Health: First 1,000 Days Special Interest Group provides an overview of the rationale, evidence, and key action steps needed to engage Community Health Workers (CHWs) into t
Externí odkaz:
https://doaj.org/article/72d257bf163049d6a361ff2cdb8b04ac
Autor:
Jigme Dorji, Amanda J. Chamberlain, Coralie M. Reich, Christy J. VanderJagt, Tuan V. Nguyen, Hans D. Daetwyler, Iona M. MacLeod
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-9 (2024)
Abstract Background Mitochondrial genomes differ from the nuclear genome and in humans it is known that mitochondrial variants contribute to genetic disorders. Prior to genomics, some livestock studies assessed the role of the mitochondrial genome bu
Externí odkaz:
https://doaj.org/article/11ddd1817ea540619d315e0ce27dd31d
Autor:
Zexi Cai, Terhi Iso-Touru, Marie-Pierre Sanchez, Naveen Kadri, Aniek C. Bouwman, Praveen Krishna Chitneedi, Iona M. MacLeod, Christy J. Vander Jagt, Amanda J. Chamberlain, Birgit Gredler-Grandl, Mirjam Spengeler, Mogens Sandø Lund, Didier Boichard, Christa Kühn, Hubert Pausch, Johanna Vilkki, Goutam Sahana
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-22 (2024)
Abstract Background Mastitis is a disease that incurs significant costs in the dairy industry. A promising approach to mitigate its negative effects is to genetically improve the resistance of dairy cattle to mastitis. A meta-analysis of genome-wide
Externí odkaz:
https://doaj.org/article/0b518444be7b41d0b9f36f33a691ad7e
Autor:
Hanna Vihma, Kelin Li, Anna Welton-Arndt, Audrey L. Smith, Kiran R. Bettadapur, Rachel B. Gilmore, Eric Gao, Justin L. Cotney, Hsueh-Cheng Huang, Jon L. Collins, Stormy J. Chamberlain, Hyeong-Min Lee, Jeffrey Aubé, Benjamin D. Philpot
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Deletion of the maternal UBE3A allele causes Angelman syndrome (AS); because paternal UBE3A is epigenetically silenced by a long non-coding antisense (UBE3A-ATS) in neurons, this nearly eliminates UBE3A protein in the brain. Reactivating pat
Externí odkaz:
https://doaj.org/article/72e7df6e4aea4466a15644b3c09e8c85
Publikováno v:
Royal Society Open Science, Vol 11, Iss 11 (2024)
The expression of behaviour can vary both among (i.e. behavioural types (BTs)) and within individuals (i.e. plasticity), and investigating causes and consequences of variation has garnered significant attention. Conversely, studies quantifying harves
Externí odkaz:
https://doaj.org/article/25e28803509a48c9871d041e814a9367
Autor:
Mohammad Ghoreishifar, Amanda J. Chamberlain, Ruidong Xiang, Claire P. Prowse-Wilkins, Thomas J. Lopdell, Mathew D. Littlejohn, Jennie E. Pryce, Michael E. Goddard
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-11 (2024)
Abstract Background Genome sequence variants affecting complex traits (quantitative trait loci, QTL) are enriched in functional regions of the genome, such as those marked by certain histone modifications. These variants are believed to influence gen
Externí odkaz:
https://doaj.org/article/909bbb2cefc147078721ba74bc8405dd
Autor:
Mehrnush Forutan, Bailey N. Engle, Amanda J. Chamberlain, Elizabeth M. Ross, Loan T. Nguyen, Michael J. D’Occhio, Alf Collins Snr, Elise A. Kho, Geoffry Fordyce, Shannon Speight, Michael E. Goddard, Ben J. Hayes
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Most genetic variants associated with fertility in mammals fall in non-coding regions of the genome and it is unclear how these variants affect fertility. Here we use genome-wide association summary statistics for Heifer puberty (pubertal or
Externí odkaz:
https://doaj.org/article/6a62bad138bb4514934e92cd1f173ef4
Autor:
Irene van den Berg, Amanda J. Chamberlain, Iona M. MacLeod, Tuan V. Nguyen, Mike E. Goddard, Ruidong Xiang, Brett Mason, Susanne Meier, Claire V. C. Phyn, Chris R. Burke, Jennie E. Pryce
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-18 (2024)
Abstract Background Female fertility is an important trait in dairy cattle. Identifying putative causal variants associated with fertility may help to improve the accuracy of genomic prediction of fertility. Combining expression data (eQTL) of genes,
Externí odkaz:
https://doaj.org/article/eb916b93e29a4197bc37af791abba3ff
Autor:
Thomas J. Lopdell, Alexander J. Trevarton, Janelle Moody, Claire Prowse-Wilkins, Sarah Knowles, Kathryn Tiplady, Amanda J. Chamberlain, Michael E. Goddard, Richard J. Spelman, Klaus Lehnert, Russell G. Snell, Stephen R. Davis, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-18 (2024)
Abstract Background Bovine lactoferrin (Lf) is an iron absorbing whey protein with antibacterial, antiviral, and antifungal activity. Lactoferrin is economically valuable and has an extremely variable concentration in milk, partly driven by environme
Externí odkaz:
https://doaj.org/article/8080a82b88cf4f85b058bde3a2e3767d