Zobrazeno 1 - 10
of 2 882
pro vyhledávání: '"J CALDWELL"'
Autor:
Brian J. Caldwell, Andrew S. Norris, Caroline F. Karbowski, Alyssa M. Wiegand, Vicki H. Wysocki, Charles E. Bell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Specific ssDNA binding proteins promote the annealing of complementary strands. Here the authors reveal an intermediate of annealing in which a duplex DNA is bound in an unusual conformation that is highly extended and unwound for the ssDNA binding p
Externí odkaz:
https://doaj.org/article/aac4a04f2d004c9b9656c68c765f8d2d
As land is lost to urban sprawl and other non-farm activity, our ability to produce food is diminished and options for future food production are limited. Farmland preservation speaks to the need to preserve the agricultural land base for future gene
Autor:
Habib Bouguenina, Stephanos Nicolaou, Yann-Vaï Le Bihan, Elizabeth A. Bowling, Cheyenne Calderon, John J. Caldwell, Brinley Harrington, Angela Hayes, P. Craig McAndrew, Costas Mitsopoulos, Fernando Jr. Sialana, Andrea Scarpino, Mark Stubbs, Arjun Thapaliya, Siddhartha Tyagi, Hannah Z. Wang, Francesca Wood, Rosemary Burke, Florence Raynaud, Jyoti Choudhary, Rob L.M. van Montfort, Amine Sadok, Thomas F. Westbrook, Ian Collins, Rajesh Chopra
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107059- (2023)
Summary: To address the limitation associated with degron based systems, we have developed iTAG, a synthetic tag based on IMiDs/CELMoDs mechanism of action that improves and addresses the limitations of both PROTAC and previous IMiDs/CeLMoDs based ta
Externí odkaz:
https://doaj.org/article/deed144041474c6d99c938d0c74b984d
Autor:
Brian J. Caldwell
Publikováno v:
Education Sciences, Vol 14, Iss 2, p 190 (2024)
The questions addressed in this essay are (1) how has the work environment of school leaders changed in the early years of the 21st century, (2) how have these changes affected the role of the school leader, (3) what is the association between an evi
Externí odkaz:
https://doaj.org/article/e4683de2746c4d9d96e01bd9d0f67c01
Autor:
Wayne J. Caldwell
Climate change and an evolving non-renewable energy sector threaten the future viability and sustainability of communities across the country. While rural communities have a special place in the national fabric, they often lack the resources to tackl
Autor:
John K. Yue, Alexander F. Haddad, Albert S. Wang, David J. Caldwell, Gray Umbach, Anthony M. Digiorgio, Phiroz E. Tarapore, Michael C. Huang, Geoffrey T. Manley
Publikováno v:
Trauma Case Reports, Vol 40, Iss , Pp 100668- (2022)
Background: Traumatic subdural hematomas (SDH) can have devastating neurologic consequences. Acute-on-chronic SDHs are more frequent in the elderly, who have increased comorbidities and perioperative risks. The subdural evacuation port system (SEPS)
Externí odkaz:
https://doaj.org/article/0a34f3b8b45848f8b4e2450b724cf807
Autor:
Facundo Scordo, Sudeep Chandra, Erin Suenaga, Suzanne J. Kelson, Joshua Culpepper, Lucia Scaff, Flavia Tromboni, Timothy J. Caldwell, Carina Seitz, Juan E. Fiorenza, Craig E. Williamson, Steven Sadro, Kevin C. Rose, Simon R. Poulson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Wildfire smoke often covers areas larger than the burned area, yet the impacts of smoke on nearby aquatic ecosystems are understudied. In the summer of 2018, wildfire smoke covered Castle Lake (California, USA) for 55 days. We quantified the
Externí odkaz:
https://doaj.org/article/6522dd6e8e634371b999370d8c0d0fcb
Publikováno v:
Journal of Medical Radiation Sciences, Vol 68, Iss 1, Pp 86-90 (2021)
Abstract Image‐guided radiation therapy (IGRT) technologies are routinely used by radiation therapists (RTs) in clinical departments. However, there is limited literature on the acquisition and assessment of IGRT image‐matching competencies in un
Externí odkaz:
https://doaj.org/article/05712f73c11e47638545c94ae251eea9
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveChildren and adolescents with recurrent and metastatic solid tumors have a poor outcome. A previous phase 1 study (ANGIO1) targeting angiogenesis with bevacizumab, sorafenib, and cyclophosphamide, demonstrated a signal of activity in a subse
Externí odkaz:
https://doaj.org/article/983947b11cd44a9298cd83179d9f1d74
Autor:
Wayne J. Caldwell
Suburbanization, affordable housing, mass transportation, loss of fertile lands -- these are modern problems, yet they are not new. Thomas Adams grappled with these same issues nearly a century ago, when he wrote Rural Planning and Development, a boo