Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J C Sarup"'
Autor:
A Ullrich, W L Wong, Gary K. Scott, H M Shepard, J C Sarup, Chris Benz, P A Montgomery, R M Johnson, J.M. Dodson
Publikováno v:
Journal of Biological Chemistry. 266:14300-14305
A partially agonistic monoclonal antibody, 4D5, known to bind to the extracellular domain of p185HER2 and shown to inhibit long term growth of p185HER2-overexpressing breast cancer cells, was used to study signal transduction and phosphotyrosyl prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbf3c7a24b82fb218a45cd00fc281106
https://doi.org/10.1016/s0021-9258(18)98683-7
https://doi.org/10.1016/s0021-9258(18)98683-7
Autor:
Malgorzata Beryt, J C Sarup, Peter Lindley, Francis W. Lau, H. Michael Shepard, James K. Liu, Jeffrey Higaki, Lisa Turin, Irene Ni, Juan Zhang, Cathleen Brdlik, James Rozzelle, Rajendra Kumari, Brett Jorgensen, Xiaomei Bai, Pei Jin, Susan A. Watson
Publikováno v:
Molecular cancer therapeutics. 7(10)
All four members of the human epidermal growth factor (EGF) receptor (HER) family are implicated in human cancers. Although efficacious in a subset of patients, resistance to single-targeted anti-HER therapy [i.e., cetuximab (Erbitux) and trastuzumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0bd4cbeb543043f8434614b3918055
https://pubmed.ncbi.nlm.nih.gov/18852126
https://pubmed.ncbi.nlm.nih.gov/18852126
Autor:
J C Sarup, C. Kent Osborne, H. Michael Shepard, Randolph M. Johnson, Gary K. Scott, Ester Coronado, Christopher C. Benz, Debasish Tripathy
Publikováno v:
Breast cancer research and treatment. 24(2)
Since the poor prognosis associated with HER2 amplified breast cancers might be explained by a mechanistic association between p185HER2 overexpression and therapeutic resistance, we assessed the chemo-endocrine sensitivity of estrogen receptor (ER) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918a2b982741c8d4fb558d48763866f9
https://pubmed.ncbi.nlm.nih.gov/8095168
https://pubmed.ncbi.nlm.nih.gov/8095168
Autor:
G K, Scott, J M, Dodson, P A, Montgomery, R M, Johnson, J C, Sarup, W L, Wong, A, Ullrich, H M, Shepard, C C, Benz
Publikováno v:
The Journal of biological chemistry. 266(22)
A partially agonistic monoclonal antibody, 4D5, known to bind to the extracellular domain of p185HER2 and shown to inhibit long term growth of p185HER2-overexpressing breast cancer cells, was used to study signal transduction and phosphotyrosyl prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc092f22799b8e30dc2c74c8ca5c3d1c
https://pubmed.ncbi.nlm.nih.gov/1677643
https://pubmed.ncbi.nlm.nih.gov/1677643
Autor:
J C, Sarup, R M, Johnson, K L, King, B M, Fendly, M T, Lipari, M A, Napier, A, Ullrich, H M, Shepard
Publikováno v:
Growth regulation. 1(2)
The HER2 protooncogene encodes a growth factor receptor-like transmembrane protein tyrosine kinase (p185HER2) whose ligand remains to be fully characterized. The overexpression of p185HER2 is implicated in aggressive forms of breast and ovarian cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5917f0ee81e458b4026c058d6b8b70bc
https://pubmed.ncbi.nlm.nih.gov/1688187
https://pubmed.ncbi.nlm.nih.gov/1688187
Autor:
Ramon Colomer, Ruth Lupu, Dennis J. Slamon, Gerhard Zugmaier, Marc E. Lippman, J C Sarup, Michael Shepard
Publikováno v:
Science (New York, N.Y.). 249(4976)
The erbB2 oncogene encodes a 185-kilodalton transmembrane protein whose sequence is similar to the epidermal growth factor receptor (EGFR). A 30-kilodalton factor (gp30) secreted from MDA-MB-231 human breast cancer cells was shown to be a ligand for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fd4a7e5fee8ba3e6d3e191709f709a
https://pubmed.ncbi.nlm.nih.gov/2218496
https://pubmed.ncbi.nlm.nih.gov/2218496
Publikováno v:
Journal of Biological Chemistry. 263:5624-5633
Each of four independent experimental approaches showed that human breast carcinoma T47D cells contain both high and low affinity progesterone receptors. (i) Equilibrium-specific [3H]progesterone binding to adherent cultured cells revealed dissociati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ba8b5f53f5260b1e402772556ca1bae
https://doi.org/10.1016/s0021-9258(18)60611-8
https://doi.org/10.1016/s0021-9258(18)60611-8
Publikováno v:
The Journal of biological chemistry. 263(12)
Each of four independent experimental approaches showed that human breast carcinoma T47D cells contain both high and low affinity progesterone receptors. (i) Equilibrium-specific [3H]progesterone binding to adherent cultured cells revealed dissociati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1582a789cd98b822ced891e340abb9c
https://pubmed.ncbi.nlm.nih.gov/3356703
https://pubmed.ncbi.nlm.nih.gov/3356703
Autor:
Chen, Michael, Sheu, Ming-Thau, Cheng, Tian-Lu, Roffler, Steve R., Lin, Shyr-Yi, Chen, Yi-Jou, Cheng, Yi-An, Cheng, Jing-Jy, Chang, Hsin-Yu, Wu, Tung-Yun, Kao, An-Pei, Ho, Yuan-Soon, Chuang, Kuo-Hsiang
Publikováno v:
Biomaterials Science (2047-4830); 1/7/2022, p202-215, 14p
Autor:
Shetty, Vivekananda1,2 vivek@immunotope.com, Philip, Ramila1
Publikováno v:
Australian Journal of Chemistry. 2013, Vol. 66 Issue 7, p770-780. 11p.