Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J C McLenithan"'
Publikováno v:
Proceedings of the National Academy of Sciences. 90:512-516
Insulin rapidly represses expression of the gene encoding the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 mouse adipocytes. Upon exposure to the hormone the cellular level of GLUT4 mRNA falls (t1/2 approximately 2.5 hr) to 20-30% of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a6a377e0cf1fc307977f2f573a6387
https://doi.org/10.1073/pnas.90.2.512
https://doi.org/10.1073/pnas.90.2.512
Publikováno v:
Proceedings of the National Academy of Sciences. 89:1812-1816
Heterologous proteins can be expressed in Xenopus laevis oocytes by cytoplasmic microinjection of mRNA. To circumvent limitations inherent in this approach we investigate direct nuclear injection of strong viral expression vectors to drive transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e909c74348ca127538647f7c7d3b6c2
https://doi.org/10.1073/pnas.89.5.1812
https://doi.org/10.1073/pnas.89.5.1812
Autor:
R D Hoffman, K H Kaestner, K Liao, R C Hresko, J R Flores-Riveros, T Kastelic, J C McLenithan, Robert J. Christy, M Janicot, M D Lane
Publikováno v:
Diabetes Care. 13:565-575
We identified the earliest events in autophosphorylation of the insulin receptor after insulin addition. Insulinstimulated autophosphorylation at specific sites in the tyrosine kinase domain of the receptor's β-subunit is correlated kinetically with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac95bdb962d8f719e2c8a27e8a2f1850
https://doi.org/10.2337/diacare.13.6.565
https://doi.org/10.2337/diacare.13.6.565
Publikováno v:
The Biochemical journal. 333
During the assembly of cell surface receptors, insulin proreceptors are sometimes joined to insulin-like growth factor (IGF) receptor precursors to form covalently linked hybrid receptors. To address the biological consequences of hybrid receptor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f802d67e07423fb4cc9fa27b2ea79e89
https://pubmed.ncbi.nlm.nih.gov/9677346
https://pubmed.ncbi.nlm.nih.gov/9677346
Autor:
W. Shillinglaw, W. J. Henzel, M D Lane, J C McLenithan, Deborah E. Geiman, Q.-Q. Tang, M.-S. Jiang
During adipogenesis, CCAAT/enhancer binding protein α (C/EBPα) serves as a pleiotropic transcriptional activator of adipocyte genes. Previously, we identified dual repressive elements in the C/EBPα gene and a putative transacting factor ( C /EBPα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8d83dbc54988912cf051bb5ebca94f
https://europepmc.org/articles/PMC19859/
https://europepmc.org/articles/PMC19859/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(5)
Glucose uptake by adipose tissue is mediated by two glucose transporters: GLUT4, which is most abundant, and GLUT1. While GLUT1 is expressed in many tissues, GLUT4 is unique to tissues that exhibit insulin-stimulated glucose uptake (heart and skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f747a05fa6909a5dc56a9221f6b812a6
https://pubmed.ncbi.nlm.nih.gov/1705711
https://pubmed.ncbi.nlm.nih.gov/1705711
Autor:
Klaus H. Kaestner, Robert J. Christy, M D Lane, P Cornelius, P H Pekala, J C McLenithan, L T Braiterman
Publikováno v:
Proceedings of the National Academy of Sciences. 86:3150-3154
The cDNAs for two putative glucose transporters from mouse 3T3-L1 adipocytes were isolated and sequenced. One of these cDNAs encodes the murine homolog of the human hepG2/erythrocyte glucose transporter, termed GT1. GT1 mRNA is most abundant in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b731fa2e5333cfc5b56de245285693d0
https://doi.org/10.1073/pnas.86.9.3150
https://doi.org/10.1073/pnas.86.9.3150
Publikováno v:
The Journal of biological chemistry. 260(21)
An enzyme catalyzing the reduction of S-(2,4-dichlorophenacyl)glutathione to 2',4'-dichloroacetophenone was purified to apparent homogeneity by ion exchange, gel filtration, and hydroxylapatite chromatography from rat hepatic cytosol. The molecular w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0ae75f0280fc879258110b082951505
https://pubmed.ncbi.nlm.nih.gov/4044577
https://pubmed.ncbi.nlm.nih.gov/4044577