Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J C McGuire"'
Autor:
J. C. Mcguire, T. A. Barf, Nabil B. Ghazal, Håkan Wikström, S. J. Peroutka, Michael D. Ennis, Kjell A. Svensson, M. W. Smith, P. de Boer
Publikováno v:
Journal of Medicinal Chemistry, 39(24), 4717-4726. AMER CHEMICAL SOC
2-[5-[[(Trifluoromethyl)sulfonyl]oxy]-1H-indol-3-yl]ethylamine (18), its N,N-di-n-propyl (12), N,N-diethyl (13), and N,N-dimethyl (14) derivatives, and 4-[3-[2-(N,N-dimethylamino)ethyl]1H-indol-3-yl]-N-(p-methoxybenzyl)acrylamide (GR46611, 19) were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be345dc40bee68af626fe2973d98fbc5
https://doi.org/10.1021/jm9604890
https://doi.org/10.1021/jm9604890
Autor:
R F Krzesicki, C A Hatfield, M J Bienkowski, J C McGuire, G E Winterrowd, D L Chapman, A E Berger, R N McEwan, D B Carter, J G Chosay
Publikováno v:
The Journal of Immunology. 150:4008-4018
The IL-1R antagonist protein (IRAP) is a competitive inhibitor of IL-1, which is predominantly synthesized by monocytes. We show that this molecule is also expressed in human synovial fibroblasts and dermal fibroblasts (CRL 1445). IRAP mRNA was regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe05f72949b21a5239f7dc50511eefa8
https://doi.org/10.4049/jimmunol.150.9.4008
https://doi.org/10.4049/jimmunol.150.9.4008
Autor:
P. de Boer, N. B. Ghazal, T. A. Barf, K. Svensson, M. W. Smith, H. Wikstroem, S. J. Peroutka, M. D. Ennis, J. C. Mcguire
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9f70025a3a9f74755462f56d7da6deb
https://doi.org/10.1002/chin.199711099
https://doi.org/10.1002/chin.199711099
Autor:
R B, McCall, A G, Romero, M J, Bienkowski, D W, Harris, J C, McGuire, M F, Piercey, M E, Shuck, M W, Smith, K A, Svensson, P J, Schreur
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(2)
The purpose of the present study was to characterize U-92016A [(+)-R)-2-cyano-N,N-dipropyl-8-amino-6,7,8,9-tetrahydro-3H-benz[e] indole] as a 5-hydroxytryptamine (5-HT)1A receptor agonist and to compare its activity with that of standard 5-HT1A recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce0e1872980bb499ace2f04a9d431c0d
https://pubmed.ncbi.nlm.nih.gov/7965808
https://pubmed.ncbi.nlm.nih.gov/7965808
Autor:
R F, Krzesicki, C A, Hatfield, M J, Bienkowski, J C, McGuire, G E, Winterrowd, D L, Chapman, A E, Berger, R N, McEwan, D B, Carter, J G, Chosay
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(9)
The IL-1R antagonist protein (IRAP) is a competitive inhibitor of IL-1, which is predominantly synthesized by monocytes. We show that this molecule is also expressed in human synovial fibroblasts and dermal fibroblasts (CRL 1445). IRAP mRNA was regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f7cebd9e31f041fd13bd2c58706a677
https://pubmed.ncbi.nlm.nih.gov/8473746
https://pubmed.ncbi.nlm.nih.gov/8473746
Publikováno v:
Methods in enzymology. 187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27e35edc415a8f305ed6d133b9eaf27d
https://pubmed.ncbi.nlm.nih.gov/2172728
https://pubmed.ncbi.nlm.nih.gov/2172728
Publikováno v:
Scopus-Elsevier
Altered subcellular distribution and activity of protein kinase C (PKC) is associated with transmembrane signalling in a variety of systems in which receptor occupancy leads to increased hydrolysis of polyphosphoinositides. Here we report evidence th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6490b69e772f3cd87fc4b944f7ab33e3
https://doi.org/10.1038/327629a0
https://doi.org/10.1038/327629a0
Autor:
Tamotsu Hayase, Hiroshi Motoda, J. C. McGuire, W. F. Brehm, A. D. Krumbein, M. Lemanska, M. Segev, J. J. Wagschal, A. Yaari, L. J. Nemeth, J. P. Thompson, G. R. McCoy, B. T. Lubin, B. M. Durst, S. R. Bierman, E. D. Clayton, J. F. Mincey, Otohiko Aizawa, Keiji Kanda, Tetsuya Nozaki, Tetsuo Matsumoto, H. K. Clark, D. C. Kocher
Publikováno v:
Nuclear Technology. 48:87-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea67b4868ab2270ebf2549980438f4b
https://doi.org/10.13182/nt80-a32454
https://doi.org/10.13182/nt80-a32454
Autor:
J C McGuire, L A Greene
Publikováno v:
Journal of Biological Chemistry. 254:3362-3367
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22911311793d92ea8f9deb2a37f4b360
https://doi.org/10.1016/s0021-9258(18)50768-7
https://doi.org/10.1016/s0021-9258(18)50768-7
Publikováno v:
Journal of Biological Chemistry. 263:13223-13230
Monoclonal antibodies (mAbs) which distinguish Type 3 protein kinase C (PKC) from Types 1 and 2 have been obtained from mice immunized with purified Type 3 PKC from rabbit brain cytosol. Most of these mAbs (seven out of eight) selectively recognize T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1ea0678bcc488cd287a1fdf14b912dd
https://doi.org/10.1016/s0021-9258(18)37695-6
https://doi.org/10.1016/s0021-9258(18)37695-6