Zobrazeno 1 - 10 of 51 pro vyhledávání: '"J C Glorioso"'
1
Development of replication-defective herpes simplex virus vectors
Autor: D, Krisky, P, Marconi, W F, Goins, J C, Glorioso
Publikováno v: Methods in molecular medicine. 7
Numerous diseases of the nervous system result from single gene or multifactorial gene defects such as cancer, immune pathological disorders, metabolic diseases, and common neurodegenerative syndromes (Parkinson's and Alzheimer's diseases). A greater
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b834f831f9104ee19843e9bd69c11db
https://pubmed.ncbi.nlm.nih.gov/24493419
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2
Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C
Autor: K E Dolter, Nina Langeland, Lars Haarr, J C Glorioso, Anne Margrete Øyan, Clyde S. Crumpacker, W F Goins
Publikováno v: Journal of Virology. 67:2434-2441
Entry of herpes simplex virus (HSV) into cells is believed to be mediated by specific binding of envelope proteins to a cellular receptor. Neomycin specifically blocks this initial step in infection by HSV-1 but not HSV-2. Resistance of HSV-2 to this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018afbed5254e174ac56ab7bb4cb787b
https://doi.org/10.1128/jvi.67.5.2434-2441.1993
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3
I kappa B-mediated apoptotic gene therapy against acute myelogenous leukemia using replication-defective HSV-1 vector expressing TK and mutant I kappa B alpha
Autor: Y, Kuwayama, T, Suzuki, S, Moriuchi, J C, Glorioso, M, Bessho
Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 51(1)
Overexpression of NF-kappa B reportedly plays anti-apoptotic roles in the growth of AML cells. Control of AML cell growth was attempted using a replication-defective herpes simplex virus-1 vector, T0I kappa B alpha, overexpressing mutant I kappa B al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc6e7eef195c153bfe839f6ec3528c77
https://pubmed.ncbi.nlm.nih.gov/16171566
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5
Herpes simplex virus mediated nerve growth factor expression in bladder and afferent neurons: potential treatment for diabetic bladder dysfunction
Autor: W F, Goins, N, Yoshimura, M W, Phelan, T, Yokoyama, M O, Fraser, H, Ozawa, J R, Bennett N, W C, de Groat, J C, Glorioso, M B, Chancellor
Publikováno v: The Journal of urology. 165(5)
Diabetic cystopathy resulting from sensory neuropathy may potentially be treated by direct gene therapy. It has been suggested that nerve growth factor (NGF) has an ameliorative effect in preventing the death in diabetes of afferent dorsal root gangl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0f003a44c45f4b88590ad588163b607
https://pubmed.ncbi.nlm.nih.gov/11342969
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6
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells
Autor: W O, Arafat, E, Casado, M, Wang, R D, Alvarez, G P, Siegal, J C, Glorioso, D T, Curiel, J, Gómez-Navarro
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(11)
We and others have proposed mammalian cells as gene delivery vehicles with the potential for overcoming physiological barriers to viral vectors. To that end, we previously have shown the potential of CD34+ endothelial progenitors for systemic gene de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90ffd173edb3100c595153bde6bb7c40
https://pubmed.ncbi.nlm.nih.gov/11106265
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7
Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints
Autor: Z, Mi, S C, Ghivizzani, E R, Lechman, D, Jaffurs, J C, Glorioso, C H, Evans, P D, Robbins
Publikováno v: Arthritis and rheumatism. 43(11)
To examine the effect of insulin-like growth factor 1 (IGF-1) on the regulation of cartilage synthesis and other articular events in vivo.A first-generation adenoviral vector expressing human IGF-1 (AdIGF-1) from the cytomegalovirus promoter was cons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e225b6ab54524701cbc7ff0a8996965d
https://pubmed.ncbi.nlm.nih.gov/11083281
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9
Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining
Autor: Q, Yao, J C, Glorioso, C H, Evans, P D, Robbins, I, Kovesdi, T J, Oligino, S C, Ghivizzani
Publikováno v: The journal of gene medicine. 2(3)
Rheumatoid arthritis (RA) is an autoimmune disease where the synovial lining layer of the joint becomes thickened, hypercellular, and highly aggressive. Invading synovial tissue erodes cartilage and subchondral bone and leads to loss of joint functio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::923d5f4b31e665fb3a694253af54bee1
https://pubmed.ncbi.nlm.nih.gov/10894267
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10
Herpes simplex virus vector-mediated dystrophin gene transfer and expression in MDX mouse skeletal muscle
Autor: G R, Akkaraju, J, Huard, E P, Hoffman, W F, Goins, R, Pruchnic, S C, Watkins, J B, Cohen, J C, Glorioso
Publikováno v: The journal of gene medicine. 1(4)
Duchenne muscular dystrophy (DMD) results from mutations that prevent the expression of functional dystrophin in muscle fibers. Herpes simplex virus type-1 (HSV-1) represents a potentially useful vector for treatment of DMD because it has the capacit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::476bde96fbc23ef9719e81a3719f5316
https://pubmed.ncbi.nlm.nih.gov/10738561
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