Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J C Garbe"'
Publikováno v:
The Biological Bulletin. 179:77-86
Although originally identified because of its abundant transcription in heat shock, the hsr-omega gene is active, at generally lower levels, in non-stressed cells. The locus produces an unusual set of three transcripts. Evidence from a variety of exp
Autor:
Martha R. Stampfer, Alain Philippe Vasserot, Serge Lichtsteiner, Gerri Levine, J C Garbe, Paul Yaswen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 98(8)
Failures to arrest growth in response to senescence or transforming growth factor β (TGF-β) are key derangements associated with carcinoma progression. We report that activation of telomerase activity may overcome both inhibitory pathways. Ectopic
Publikováno v:
Cancer research. 59(20)
We have uncovered a novel role for the cyclin-dependent kinase inhibitor, p57KIP2, during the immortalization of cultured human mammary epithelial cells (HMECs). HMECs immortalized after chemical carcinogen exposure initially expressed little or no t
Publikováno v:
Genetics. 139(4)
The Drosophila melanogaster Hsr-omega locus produces a nuclear RNA containing > 5 kb of tandem repeat sequences. These repeats are unique to Hsr-omega and show concerted evolution similar to that seen with classical satellite DNAs. In D. melanogaster
Autor:
Mark W. Jackson, Bernard W. Futscher, Mark A. LaBarge, Martha R. Stampfer, Lukas Vrba, J C Garbe
Publikováno v:
Cancer Research. 71:A41-A41
Breast cancers display great phenotypic and molecular diversity. Based on these differences, ∼5 breast cancer subtypes have been categorized; importantly, these subtypes show major differences in clinical parameters. Etiology and progression likely
Publikováno v:
Journal of Biological Chemistry. 261:16889-16894
Cytological studies have shown that the heat shock loci 93D of Drosophila melanogaster and 2-48B of Drosophila hydei have several characteristics which suggest that they are homologous loci, yet sequence homology is barely detectable by cross-hybridi
Publikováno v:
Journal of Bacteriology. 149:1112-1119
The first generalized transducing bacteriophage reported for Bacillus megaterium has been characterized. Optimum conditions for lysate production and transduction procedures were established so that transducing frequencies of 8 x 10(-6) and higher ar
Publikováno v:
Journal of bacteriology. 157(2)
Genes involved in the biosynthesis of leucine have been mapped in Bacillus megaterium QM B1551, using transducing phage MP13. Mutations were designated leuA, leuB, or leuC on the basis of enzyme assays. Two mutant strains were deficient in the enzyme
Publikováno v:
The Journal of Cell Biology
The Drosophila hsr omega locus produces one of the largest and most active heat shock puffs, yet it does not encode a heat shock protein. Instead, this locus produces a distinctive set of three transcripts, all from the same start site. The largest t
Publikováno v:
Results and problems in cell differentiation. 14